Robert W. Shafer
Publication Details
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Nucleic acid template and the risk of a PCR-Induced HIV-1 drug resistance mutation.
PLoS One. 2010; (6): e10992
The HIV-1 nucleoside RT inhibitor (NRTI)-resistance mutation, K65R confers intermediate to high-level resistance to the NRTIs abacavir, didanosine, emtricitabine, lamivudine, and tenofovir; and low-level resistance to stavudine. Several lines of evidence suggest that K65R is more common in HIV-1 subtype C than subtype B viruses.
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