Dolly B. Tyan, PhD
Publication Details
-
New approaches for detecting complement-fixing antibodies.
Curr Opin Organ Transplant. 2012; (4): 409-15
Complement-fixing human leukocyte antigen (HLA) antibodies are a contraindication to solid organ transplant. Newer solid phase assays for HLA antibody definition have created treatment quandaries because many more antibodies are detected by these methods. It is unclear which of the antibodies identified are clinically relevant as all IgG-binding antibodies are detected whether they can fix complement or not.
Help