Uta Francke
Publication Details
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Induced chromosome deletion in a Williams-Beuren syndrome mouse model causes cardiovascular abnormalities.
J Vasc Res. 2011; (2): 119-29
The Williams-Beuren syndrome (WBS) is a genetic disorder caused by a heterozygous ~1.5-Mb deletion. The aim of this study was to determine how the genetic changes in a Wbs mouse model alter Eln expression, blood pressure, vessel structure, and abdominal aortic wall dynamics in vivo.
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