Community Academic Profiles

Edgar Engleman

Publication Details

  • Systemic antitumor effect of intratumoral injection of dendritic cells in combination with local photodynamic therapy.

    Saji H, Song W, Furumoto K, Kato H, Engleman EG. Clin Cancer Res. 2006; 12 (8): 2568-74

    Photodynamic therapy (PDT), which is used clinically for the palliative treatment of cancer, induces local tumor cell death but has no effect on tumors in untreated sites. The purpose of this study was to determine if local PDT followed by intratumoral injection of naïve dendritic cells (IT-DC) induces systemic antitumor immunity that can inhibit the growth of untreated as well as PDT + IT-DC-treated tumors.

    PubMedID: 16638867

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