Antonio Hardan
Publication Details
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A randomized controlled pilot trial of oral N-acetylcysteine in children with autism.
Biol Psychiatry. 2012; (11): 956-61
An imbalance in the excitatory/inhibitory systems with abnormalities in the glutamatergic pathways has been implicated in the pathophysiology of autism. Furthermore, chronic redox imbalance was also recently linked to this disorder. The goal of this pilot study was to assess the feasibility of using oral N-acetylcysteine (NAC), a glutamatergic modulator and an antioxidant, in the treatment of behavioral disturbance in children with autism.
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