Community Academic Profiles

D. Craig Miller, M.D.

Publication Details

  • Effects of undersized mitral annuloplasty on regional transmural left ventricular wall strains and wall thickening mechanisms.

    Cheng A, Nguyen TC, Malinowski M, Liang D, Daughters GT, Ingels NB, Miller DC. Circulation. 2006; 114 (1 Suppl): I600-9

    Undersized mitral annuloplasty, widely used for ischemic and functional mitral regurgitation (MR), has been proposed as an "annular solution to a ventricular problem." Beyond relief of MR, it is thought to improve global left ventricular (LV) shape, hence potentially reducing myocardial stress and promoting beneficial reverse LV remodeling. We previously observed that undersized annuloplasty inhibited systolic wall thickening at the LV base near the mitral annulus. In this study, we measured the effects of undersized annuloplasty on regional transmural LV wall fiber and sheet strains and wall thickening mechanisms.

    PubMedID: 16820645

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