James Chang
Publication Details
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In vitro analysis of transforming growth factor-beta1 inhibition in novel transgenic SBE-luciferase mice.
Ann Plast Surg. 2007; (2): 207-13
Transforming growth factor beta1 (TGF-beta1) expression correlates with scarring. A novel transgenic mouse model with a Smad2/3-responsive luciferase reporter construct (SBE-luc) has been developed. We hypothesized that bioluminescence in SBE-luc dermal fibroblasts could be measured to assess TGF-beta1 inhibition.
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