Zhen Cheng
Publication Details
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In Vitro and In Vivo Uncaging and Bioluminescence Imaging by using Photocaged Upconversion Nanoparticles.
Angew Chem Int Ed Engl. 2012
Bioconjugation of photocaged D-luciferin with upconversion nanoparticles (UCNPs) for uncaging and bioluminescence imaging is reported by X. Liu, B. Xing, and co-workers in their Communication (DOI: 10.1002/anie.201107919). Photon upconversion of near-infrared light by the biocompatible UCNPs causes D-luciferin to be released from the surface of the UCNPs, which results in enhanced bioluminescence signals in vitro and in vivo with deep light penetration and minimum cell damage.
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