Community Academic Profiles

Jayakumar Rajadas

Publication Details

  • Anomalous temperature dependence of peptide films at air-water interface.

    Jayakumar R, Murugesan M. Bioorg Med Chem Lett. 2000; 10 (10): 1055-7

    The tetrapeptide derivative Tyr-Gly-Phe-Ala-OBz (1) forms monolayers as confirmed by compressibility studies carried out at various temperatures. Peptide 1 monolayer exhibits an anomalous structural transition at 40 degrees C as evidenced by pi-A isotherms recorded at different temperatures. The structural transition is also observed in aqueous solution of trifluoroacetate of peptide 1 as evidenced by fluorescence and Raman scattering intensity measurements.

    PubMedID: 10843215

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