Martin S. Angst
Publication Details
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Blockade of the complement C5a receptor reduces incisional allodynia, edema, and cytokine expression.
Anesthesiology. 2006; (6): 1274-82
Activation of the complement system is one component of the inflammatory response. Various components of the complement system participate in killing foreign organisms, recruiting immune cells, enhancing edema, and stimulating cytokine formation. Complement-mediated enhancement of the inflammation surrounding surgical incisions may increase pain.
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