Community Academic Profiles

David A. Spain, MD

Publication Details

  • Massive transfusion protocols: the role of aggressive resuscitation versus product ratio in mortality reduction.

    Riskin DJ, Tsai TC, Riskin L, Hernandez-Boussard T, Purtill M, Maggio PM, Spain DA, Brundage SI. J Am Coll Surg. 2009; 209 (2): 198-205

    Exsanguinating hemorrhage necessitating massive blood product transfusion is associated with high mortality rates. Recent data suggest that altering the fresh frozen plasma to packed red blood cell ratio (FFP:PRBC) results in significant mortality reductions. Our purpose was to evaluate mortality and blood product use in the context of a newly initiated massive transfusion protocol (MTP).

    PubMedID: 19632596

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