Derrick Wan
Publication Details
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Differential expression of sclerostin in adult and juvenile mouse calvariae.
Plast Reconstr Surg. 2011; (2): 595-602
An understanding of the molecular mechanisms controlling bone formation is central to skeletal tissue engineering efforts. The observation that immature animals are able to heal calvarial defects while adult animals are not has proven to be a useful tool for examining these mechanisms. Thus, the authors compared expression of sclerostin, a bone inhibitor, between the calvariae of juvenile and adult mice.
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