John Brock-Utne
Publication Details
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The action of commonly used antiemetics on the lower oesophageal sphincter.
Br J Anaesth. 1978; (3): 295-8
The effects of five antiemetic drugs on the lower oesophageal sphincter (LOS) were studied in five groups, each comprising eight healthy volunteers. Cyclizine, prochlorperazine and metoclopramide have a desirable functional effect on LOS, while promethazine and droperidol were associated with evidence of increased gastro-oesophageal reflux.
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