Community Academic Profiles

John Brock-Utne

Publication Details

  • Hypothesis: volatile anaesthetic agents enhance transplacental exchange between mother and fetus. A preliminary study of fetal scalp blood gas changes associated with enflurane anaesthesia.

    Downing JW, Fairbrother PE, Buley RJ, Brock-Utne JG, Kambaran SR, Macpherson TA. S Afr Med J. 1979; 55 (1): 17-20

    A hypothesis that volatile anaesthetic agents, represented by enflurane, facilitate transplacental exchange was tested by simultaneous blood sampling of both mother and fetus. A trend towards improved fetal scalp blood gas status and maternal-to-fetal acid-base matching was observed with enflurane. Our results encourage further research into the feasibility of intra-uterine fetal resuscitation by anaesthetically induced promotion of intervillous perfusion.

    PubMedID: 34236

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