John Brock-Utne
Publication Details
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Intravenous midazolam does not change lower oesophageal sphincter pressure.
S Afr Med J. 1983; (26): 1024-5
The effect of intravenous midazolam 0.3 mg/kg on lower oesophageal sphincter (LOS) pressure was studied in 8 healthy volunteers. No effect on LOS pressure was noted. The importance of this finding in relation to the possible danger of gastro-oesophageal reflux and pulmonary aspiration of gastric acid content during induction of general anaesthesia is discussed.
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