Publications
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Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly.
Neveu G,
Barouch-Bentov R, Ziv-Av A, Gerber D, Jacob Y, Einav S.
PLoS Pathog.
2012;
8
(8):
e1002845
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A small molecule inhibits HCV replication and alters NS4B's subcellular distribution.
Bryson PD,
Cho NJ, Einav S, Lee C, Tai V, Bechtel J, Sivaraja M, Roberts C, Schmitz U, Glenn JS.
Antiviral Res.
2010;
87
(1):
1-8
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Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems.
Parameswaran P,
Sklan E, Wilkins C, Burgon T, Samuel MA, Lu R, Ansel KM, Heissmeyer V, Einav S, Jackson W, Doukas T, Paranjape S, Polacek C, dos Santos FB, Jalili R, Babrzadeh F, Gharizadeh B, Grimm D, Kay M, Koike S, Sarnow P, Ronaghi M, Ding SW, Harris E, Chow M, Diamond MS, Kirkegaard K, Glenn JS, Fire AZ.
PLoS Pathog.
2010;
6
(2):
e1000764
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The hepatitis C virus (HCV) NS4B RNA binding inhibitor clemizole is highly synergistic with HCV protease inhibitors.
Einav S,
Sobol HD, Gehrig E, Glenn JS.
J Infect Dis.
2010;
202
(1):
65-74
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Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis.
Einav S,
Gerber D, Bryson PD, Sklan EH, Elazar M, Maerkl SJ, Glenn JS, Quake SR.
Nat Biotechnol.
2008;
26
(9):
1019-27
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The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without Ha-ras co-transfection.
Einav S,
Sklan EH, Moon HM, Gehrig E, Liu P, Hao Y, Lowe AW, Glenn JS.
Hepatology.
2008;
47
(3):
827-35
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Mechanisms of resistance to antiviral agents.
Shafer RW,
Einav S, Chou S.
In Manual of clinical microbiology, 9th edition, Murray PR ed, Baron EJ ed, Jorgensen JH ed, Pfaller MA ed, Tenover FC ed, and Yolken RH ed. American Society of Microbiology..
2007:
1689-04
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TBC1D20 is a Rab1 GTPase-activating protein that mediates hepatitis C virus replication.
Sklan EH,
Serrano RL, Einav S, Pfeffer SR, Lambright DG, Glenn JS.
J Biol Chem.
2007;
282
(50):
36354-61
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A nucleotide binding motif in hepatitis C virus (HCV) NS4B mediates HCV RNA replication.
Einav S,
Elazar M, Danieli T, Glenn JS.
J Virol.
2004;
78
(20):
11288-95
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Prenylation inhibitors: a novel class of antiviral agents.
Einav S,
Glenn JS.
J Antimicrob Chemother.
2003;
52
(6):
883-6
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Complement C4 is protective for lupus disease independent of C3.
Einav S,
Pozdnyakova OO, Ma M, Carroll MC.
J Immunol.
2002;
168
(3):
1036-41
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Immunopathogenesis of hepatitis C virus in the immunosuppressed host.
Einav S,
Koziel MJ.
Transpl Infect Dis.
2002;
4
(2):
85-92