Publications
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Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth.
Gupta RA,
Wang D, Katkuri S, Wang H, Dey SK, DuBois RN.
Nat Med.
2004;
10
(3):
245-7
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Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer.
Gupta RA,
Tejada LV, Tong BJ, Das SK, Morrow JD, Dey SK, DuBois RN.
Cancer Res.
2003;
63
(5):
906-11
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Peroxisome proliferator-activated receptor gamma-mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms.
Gupta RA,
Sarraf P, Mueller E, Brockman JA, Prusakiewicz JJ, Eng C, Willson TM, DuBois RN.
J Biol Chem.
2003;
278
(25):
22669-77
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Expression of hypoxia-inducible factors in the peri-implantation mouse uterus is regulated in a cell-specific and ovarian steroid hormone-dependent manner. Evidence for differential function of HIFs during early pregnancy.
Daikoku T,
Matsumoto H, Gupta RA, Das SK, Gassmann M, DuBois RN, Dey SK.
J Biol Chem.
2003;
278
(9):
7683-91
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Peroxisome proliferator-activated receptor gamma and transforming growth factor-beta pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22.
Gupta RA,
Sarraf P, Brockman JA, Shappell SB, Raftery LA, Willson TM, DuBois RN.
J Biol Chem.
2003;
278
(9):
7431-8
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Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2.
Gupta RA,
Dubois RN.
Nat Rev Cancer.
2001;
1
(1):
11-21
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15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells.
Shappell SB,
Gupta RA, Manning S, Whitehead R, Boeglin WE, Schneider C, Case T, Price J, Jack GS, Wheeler TM, Matusik RJ, Brash AR, Dubois RN.
Cancer Res.
2001;
61
(2):
497-503
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Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells.
Gupta RA,
Brockman JA, Sarraf P, Willson TM, DuBois RN.
J Biol Chem.
2001;
276
(32):
29681-7
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Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor kappa B-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells.
Gupta RA,
Polk DB, Krishna U, Israel DA, Yan F, DuBois RN, Peek RM.
J Biol Chem.
2001;
276
(33):
31059-66
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Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer.
Gupta RA,
Tan J, Krause WF, Geraci MW, Willson TM, Dey SK, DuBois RN.
Proc Natl Acad Sci U S A.
2000;
97
(24):
13275-80
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Translational studies on Cox-2 inhibitors in the prevention and treatment of colon cancer.
Gupta RA,
DuBois RN.
Ann N Y Acad Sci.
2000:
910
196-204; discussion 204-6
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Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells.
Brockman JA,
Gupta RA, Dubois RN.
Gastroenterology.
1998;
115
(5):
1049-55
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