Publications
-
Progress in understanding the genetics of bronchopulmonary dysplasia.
Shaw GM,
O'Brodovich HM.
Semin Perinatol.
2013;
37
(2):
85-93
-
Risk of bronchopulmonary dysplasia by second trimester maternal serum levels of alpha-fetoprotein, human chorionic gonadotrophin and unconjugaged Estriol
Jelliffe-Pawlowski LL,
Shaw G, Stevenson D, Oehlert JW, Quaintance C, Santos AJ, Baer RJ, Currier RJ, O'Brodovich H, Gould JB.
Pediatric Research.
2012;
71
(4):
399-406
-
Lung-derived soluble mediators are pathogenic in ventilator-induced lung injury
Jaecklin T,
Engelberts D, Otulakowski G, O'Brodovich H, Post M, Kavanagh BP.
Am J Physiol Lung Cell Mol Physiol.
2011:
300
L648-L658
-
Long-term terbutaline exposure stimulates alpha1-Na+-K+-ATPase expression at posttranscriptional level in rat fetal distal lung epithelial cells.
Rahman MS,
Gandhi S, Otulakowski G, Duan W, Sarangapani A, O'Brodovich H.
Am J Physiol Lung Cell Mol Physiol.
2010;
298
(1):
L96-L104
-
NHLBI training workshop report: The vanishing pediatric pulmonary investigator and recommendations for recovery.
Ferkol T,
Zeitlin P, Abman S, Blaisdell CJ, O'Brodovich H.
Pediatr Pulmonol.
2010;
45
(1):
25-33
-
A scientist track investigator program to support early career outcomes for clinician scientists.
Rosenblum ND,
Bazett-Jones DP, O'Brodovich H.
J Pediatr.
2009;
155
(5):
603-4.e1
-
Global and gene-specific translational regulation in rat lung development.
Otulakowski G,
Duan W, O'Brodovich H.
Am J Respir Cell Mol Biol.
2009;
40
(5):
555-67
-
Glucocorticoid-mediated repression of REDD1 mRNA expression in rat fetal distal lung epithelial cells.
Otulakowski G,
Duan W, Sarangapani A, Gandhi S, O'Brodovich H.
Pediatr Res.
2009;
65
(5):
514-9
-
Protease-activated receptor (Par)1 alters bioelectric properties of distal lung epithelia without compromising barrier function.
Moraes TJ,
Rafii B, Niessen F, Suzuki T, Martin R, Vachon E, Vogel W, Ruf W, O'Brodovich H, Downey GP.
Exp Lung Res.
2009;
35
(2):
136-54
-
Pulmonary neuroendocrine cell-secreted factors may alter fetal lung liquid clearance.
Gandhi SG,
Law C, Duan W, Otulakowski G, O'Brodovich H.
Pediatr Res.
2009;
65
(3):
274-8
-
Amiloride-insensitive Na+ and fluid absorption in the mammalian distal lung.
O'Brodovich H,
Yang P, Gandhi S, Otulakowski G.
Am J Physiol Lung Cell Mol Physiol.
2008;
294
(3):
L401-8
-
Visualizing water clearance in the lung with MRI.
Vidarsson L,
Helm E, O'Brodovich H, Macgowan CK.
Magn Reson Med.
2008;
60
(1):
230-5
-
Amiloride-insensitive nasal potential difference varies with the menstrual cycle in cystic fibrosis.
Sweezey NB,
Smith D, Corey M, Ellis L, Carpenter S, Tullis DE, Durie P, O'Brodovich HM.
Pediatr Pulmonol.
2007;
42
(6):
519-24
-
Effects of cardiogenic edema fluid on ion and fluid transport in the adult lung.
Gandhi SG,
Rafii B, Harris MS, Garces A, Mahuran D, Chen XJ, Bao HF, Jain L, Eaton DC, Otulakowski G, O'Brodovich H.
Am J Physiol Lung Cell Mol Physiol.
2007;
293
(3):
L651-9
-
Performance of a career development and compensation program at an academic health science center.
O'Brodovich H,
Beyene J, Tallett S, MacGregor D, Rosenblum ND.
Pediatrics.
2007;
119
(4):
e791-7
-
Steroid and oxygen effects on eIF4F complex, mTOR, and ENaC translation in fetal lung epithelia.
Otulakowski G,
Duan W, Gandhi S, O'brodovich H.
Am J Respir Cell Mol Biol.
2007;
37
(4):
457-66
-
The role of alpha-, beta-, and gamma-ENaC subunits in distal lung epithelial fluid absorption induced by pulmonary edema fluid.
Elias N,
Rafii B, Rahman M, Otulakowski G, Cutz E, O'Brodovich H.
Am J Physiol Lung Cell Mol Physiol.
2007;
293
(3):
L537-45
-
Thyroid hormone and Na+-K+-ATPase: more than simple transcription.
Otulakowski G,
O'Brodovich H.
Am J Physiol Lung Cell Mol Physiol.
2007;
292
(1):
L4-5
-
Clinical and education workload measurements using personal digital assistant-based software.
MacGregor DL,
Tallett S, MacMillan S, Gerber R, O'Brodovich H.
Pediatrics.
2006;
118
(4):
e985-91
-
Fluid clearance from the lungs of newborns, infants and children.
O'Brodovich H,
Paediatr Respir Rev.
2006:
7 Suppl 1
S62-3
-
Oxygen and glucocorticoids modulate alphaENaC mRNA translation in fetal distal lung epithelium.
Otulakowski G,
Rafii B, Harris M, O'Brodovich H.
Am J Respir Cell Mol Biol.
2006;
34
(2):
204-12
-
Fitness to fly in an infant with congenital lobar emphysema.
MacLean JE,
Manson D, Gray G, O'Brodovich H.
Aviat Space Environ Med.
2005;
76
(10):
989-91
-
Pulmonary edema in infants and children.
O'Brodovich H,
Curr Opin Pediatr.
2005;
17
(3):
381-4
-
Acquisition of competencies during the pediatric residency: a Canadian perspective.
Tallett S,
O'Brodovich H.
J Pediatr.
2004;
144
(3):
289-90
-
Airspace fluid clearance in the normal and edematous newborn lung: cardiogenic pulmonary edema fluid alters the clearance of airspace fluid.
O'Brodovich H,
Pediatr Pulmonol Suppl.
2004:
26
121-2
-
Deficient Na+ channel expression in newborn respiratory distress syndrome.
O'Brodovich H,
Pediatr Pulmonol Suppl.
2004:
26
141-2
-
Differential translational efficiency of ENaC subunits during lung development.
Otulakowski G,
Rafii B, O'Brodovich H.
Am J Respir Cell Mol Biol.
2004;
30
(6):
862-70
-
Expression of epithelial sodium channel alpha-subunit mRNAs with alternative 5'-untranslated regions in the developing human lung.
Banasikowska K,
Post M, Cutz E, O'Brodovich H, Otulakowski G.
Am J Physiol Lung Cell Mol Physiol.
2004;
287
(3):
L608-15
-
Low expression of human epithelial sodium channel in airway epithelium of preterm infants with respiratory distress.
Helve O,
Pitkänen OM, Andersson S, O'Brodovich H, Kirjavainen T, Otulakowski G.
Pediatrics.
2004;
113
(5):
1267-72
-
Pediatric Chairs of Canada: academic pediatric workforce.
Scott B,
Frewen T, O'Brodovich H.
J Pediatr.
2004;
145
(4):
425-6
-
Evaluation of a peer-reviewed career development and compensation program for physicians at an academic health science center.
O'Brodovich H,
Pleinys R, Laxer R, Tallett S, Rosenblum N, Sass-Kortsak C.
Pediatrics.
2003;
111
(1):
e26-31
-
Promoter analysis of the gene encoding the beta-subunit of the rat amiloride-sensitive epithelial sodium channel.
Bremner HR,
Freywald T, O'Brodovich HM, Otulakowski G.
Am J Physiol Lung Cell Mol Physiol.
2002;
282
(1):
L124-34
-
Pulmonary interstitial glycogenosis: a new variant of neonatal interstitial lung disease.
Canakis AM,
Cutz E, Manson D, O'Brodovich H.
Am J Respir Crit Care Med.
2002;
165
(11):
1557-65
-
Pulmonary oedema fluid induces non-alpha-ENaC-dependent Na(+) transport and fluid absorption in the distal lung.
Rafii B,
Gillie DJ, Sulowski C, Hannam V, Cheung T, Otulakowski G, Barker PM, O'Brodovich H.
J Physiol.
2002;
544
(Pt 2):
537-48
-
Career development and compensation: strategies for physicians in academic health science centers. A perspective from a Canadian academic health science center.
O'Brodovich H,
J Pediatr.
2001;
139
(2):
171-2
-
Expression of alpha-, beta-, and gamma-hENaC mRNA in the human nasal, bronchial, and distal lung epithelium.
Pitkänen OM,
Smith D, O'Brodovich H, Otulakowski G.
Am J Respir Crit Care Med.
2001;
163
(1):
273-6
-
Fetal lung liquid secretion: insights using the tools of inhibitors and genetic knock-out experiments.
O'Brodovich H,
Am J Respir Cell Mol Biol.
2001;
25
(1):
8-10
-
Pulmonary edema fluid movement within the lung.
O'Brodovich H,
Am J Physiol Lung Cell Mol Physiol.
2001;
281
(6):
L1324-6
-
Translational activation and repression by distinct elements within the 5'-UTR of ENaC alpha-subunit mRNA.
Otulakowski G,
Freywald T, Wen Y, O'Brodovich H.
Am J Physiol Lung Cell Mol Physiol.
2001;
281
(5):
L1219-31
-
Epithelial Na(+) channel (ENaC) expression in the developing normal and abnormal human perinatal lung.
Smith DE,
Otulakowski G, Yeger H, Post M, Cutz E, O'Brodovich HM.
Am J Respir Crit Care Med.
2000;
161
(4 Pt 1):
1322-31
-
Oxygen induction of epithelial Na(+) transport requires heme proteins.
Rafii B,
Coutinho C, Otulakowski G, O'Brodovich H.
Am J Physiol Lung Cell Mol Physiol.
2000;
278
(2):
L399-406
-
Preventing endotoxin-stimulated alveolar macrophages from decreasing epithelium Na+ channel (ENaC) mRNA levels and activity.
Dickie AJ,
Rafii B, Piovesan J, Davreux C, Ding J, Tanswell AK, Rotstein O, O'Brodovich H.
Pediatr Res.
2000;
48
(3):
304-10
-
Transplant immunosuppression increases and prolongs transgene expression following adenoviral-mediated transfection of rat lungs.
Cassivi SD,
Liu M, Boehler A, Pierre A, Tanswell AK, O'Brodovich H, Mullen JB, Slutsky AS, Keshavjee SH.
J Heart Lung Transplant.
2000;
19
(10):
984-94
-
Alternate funding arrangements to compensate physicians at academic health science centers.
O'Brodovich H,
J Pediatr Gastroenterol Nutr.
1999;
29
(1):
8-9
-
HSC clinical trials controversy continues. Hospital for Sick Children.
Buchwald M,
O'Brodovich H.
Nat Med.
1999;
5
(1):
2-3
-
Hormonal regulation and genomic organization of the human amiloride-sensitive epithelial sodium channel alpha subunit gene.
Chow YH,
Wang Y, Plumb J, O'Brodovich H, Hu J.
Pediatr Res.
1999;
46
(2):
208-14
-
Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer.
Lechardeur D,
Sohn KJ, Haardt M, Joshi PB, Monck M, Graham RW, Beatty B, Squire J, O'Brodovich H, Lukacs GL.
Gene Ther.
1999;
6
(4):
482-97
-
Regulation of an amiloride-sensitive Na+-permeable channel by a beta2-adrenergic agonist, cytosolic Ca2+ and Cl- in fetal rat alveolar epithelium.
Marunaka Y,
Niisato N, O'Brodovich H, Eaton DC.
J Physiol.
1999:
515 ( Pt 3)
669-83
-
Roles of Ca2+ and protein tyrosine kinase in insulin action on cell volume via Na+ and K+ channels and Na+/K+/2Cl- cotransporter in fetal rat alveolar type II pneumocyte.
Marunaka Y,
Niisato N, O'Brodovich H, Post M, Tanswell AK.
J Membr Biol.
1999;
168
(1):
91-101
-
Sodium channels in alveolar epithelial cells: molecular characterization, biophysical properties, and physiological significance.
Matalon S,
O'Brodovich H.
Annu Rev Physiol.
1999:
61
627-61
-
Structure and hormone responsiveness of the gene encoding the alpha-subunit of the rat amiloride-sensitive epithelial sodium channel.
Otulakowski G,
Rafii B, Bremner HR, O'Brodovich H.
Am J Respir Cell Mol Biol.
1999;
20
(5):
1028-40
-
Comparison between intratracheal and intravenous administration of liposome-DNA complexes for cystic fibrosis lung gene therapy.
Griesenbach U,
Chonn A, Cassady R, Hannam V, Ackerley C, Post M, Tanswell AK, Olek K, O'Brodovich H, Tsui L-C.
Gene Ther.
1998;
5
(2):
181-8
-
Covalent heparin cofactor II-heparin and heparin cofactor II-dermatan sulfate complexes. Characterization of novel anticoagulants.
Monagle P,
Berry L, O'Brodovich H, Andrew M, Chan A.
J Biol Chem.
1998;
273
(50):
33566-71
-
Effect of a novel covalent antithrombin-heparin complex on thrombin generation on fetal distal lung epithelium.
Chan AK,
Berry L, Mitchell L, Baranowski B, O'Brodovich H, Andrew M.
Am J Physiol.
1998;
274
(6 Pt 1):
L914-21
-
Female gender hormones regulate mRNA levels and function of the rat lung epithelial Na channel.
Sweezey N,
Tchepichev S, Gagnon S, Fertuck K, O'Brodovich H.
Am J Physiol.
1998;
274
(2 Pt 1):
C379-86
-
Influence of mechanical stretch on thrombin regulation by fetal mixed lung cells.
Chan AK,
Baranowski B, Berry L, Liu M, Rafii B, Post M, O'Brodovich H, Monagle P, Andrew M.
Am J Respir Cell Mol Biol.
1998;
19
(3):
419-25
-
Inhibition of amiloride-sensitive sodium-channel activity in distal lung epithelial cells by nitric oxide.
Ding JW,
Dickie J, O'Brodovich H, Shintani Y, Rafii B, Hackam D, Marunaka Y, Rotstein OD.
Am J Physiol.
1998;
274
(3 Pt 1):
L378-87
-
Investigation of the anticoagulant mechanisms of a covalent antithrombin-heparin complex.
Berry L,
Stafford A, Fredenburgh J, O'Brodovich H, Mitchell L, Weitz J, Andrew M, Chan AK.
J Biol Chem.
1998;
273
(52):
34730-6
-
Liposome-mediated transfection of fetal lung epithelial cells: DNA degradation and enhanced superoxide toxicity.
Tanswell AK,
Staub O, Iles R, Belcastro R, Cabacungan J, Sedlackova L, Steer B, Wen Y, Hu J, O'Brodovich H.
Am J Physiol.
1998;
275
(3 Pt 1):
L452-60
-
Modulation of aquaporin 4 and the amiloride-inhibitable sodium channel in perinatal rat lung epithelial cells.
Ruddy MK,
Drazen JM, Pitkanen OM, Rafii B, O'Brodovich HM, Harris HW.
Am J Physiol.
1998;
274
(6 Pt 1):
L1066-72
-
O2-induced ENaC expression is associated with NF-kappaB activation and blocked by superoxide scavenger.
Rafii B,
Tanswell AK, Otulakowski G, Pitkänen O, Belcastro-Taylor R, O'Brodovich H.
Am J Physiol.
1998;
275
(4 Pt 1):
L764-70
-
Relation between alpha, beta, and gamma human amiloride- sensitive epithelial Na+ channel mRNA levels and nasal epithelial potential difference in healthy men.
Otulakowski G,
Flueckiger-Staub S, Ellis L, Ramlall K, Staub O, Smith D, Durie P, O'Brodovich H.
Am J Respir Crit Care Med.
1998;
158
(4):
1213-20
-
Significance of ion transport during lung development and in respiratory disease of the newborn.
Pitkänen OM,
O'Brodovich HM.
Ann Med.
1998;
30
(2):
134-42
-
Active 22Na+ transport by the intact lung during early postnatal life.
O'Brodovich HM,
Mullen B, Hannam VL, Goodman BE.
Can J Physiol Pharmacol.
1997;
75
(5):
431-5
-
Covalent antithrombin-heparin complexes with high anticoagulant activity. Intravenous, subcutaneous, and intratracheal administration.
Chan A,
Berry L, O'Brodovich H, Klement P, Mitchell L, Baranowski B, Monagle P, Andrew M.
J Biol Chem.
1997;
272
(35):
22111-7
-
Development of an epithelium-specific expression cassette with human DNA regulatory elements for transgene expression in lung airways.
Chow YH,
O'Brodovich H, Plumb J, Wen Y, Sohn KJ, Lu Z, Zhang F, Lukacs GL, Tanswell AK, Hui CC, Buchwald M, Hu J.
Proc Natl Acad Sci U S A.
1997;
94
(26):
14695-700
-
Lung disease in mice with cystic fibrosis.
Kent G,
Iles R, Bear CE, Huan LJ, Griesenbach U, McKerlie C, Frndova H, Ackerley C, Gosselin D, Radzioch D, O'Brodovich H, Tsui LC, Buchwald M, Tanswell AK.
J Clin Invest.
1997;
100
(12):
3060-9
-
Respiratory distress syndrome: the importance of effective transport.
O'Brodovich HM,
J Pediatr.
1997;
130
(3):
342-4
-
The effect of brefeldin A on terbutaline-induced sodium absorption in fetal rat distal lung epithelium.
Ito Y,
Niisato N, O'Brodovich H, Marunaka Y.
Pflugers Arch.
1997;
434
(4):
492-4
-
The present and future role of gene therapy in the newborn.
Tanswell AK,
O'Brodovich HM.
Curr Opin Pediatr.
1997;
9
(2):
141-5
-
Immature epithelial Na+ channel expression is one of the pathogenetic mechanisms leading to human neonatal respiratory distress syndrome.
O'Brodovich HM,
Proc Assoc Am Physicians.
1996;
108
(5):
345-55
-
Increased Po2 alters the bioelectric properties of fetal distal lung epithelium.
Pitkänen O,
Tanswell AK, Downey G, O'Brodovich H.
Am J Physiol.
1996;
270
(6 Pt 1):
L1060-6
-
Fetal lung cell-derived matrix alters distal lung epithelial ion transport.
Pitkänen OM,
Tanswell AK, O'Brodovich HM.
Am J Physiol.
1995;
268
(5 Pt 1):
L762-71
-
Lung epithelial Na channel subunits are differentially regulated during development and by steroids.
Tchepichev S,
Ueda J, Canessa C, Rossier BC, O'Brodovich H.
Am J Physiol.
1995;
269
(3 Pt 1):
C805-12
-
Lung fluid restriction affects growth but not airway branching of embryonic rat lung.
Souza P,
O'Brodovich H, Post M.
Int J Dev Biol.
1995;
39
(4):
629-37
-
The role of active Na+ transport by lung epithelium in the clearance of airspace fluid.
O'Brodovich HM,
New Horiz.
1995;
3
(2):
240-7
-
An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane.
Rotin D,
Bar-Sagi D, O'Brodovich H, Merilainen J, Lehto VP, Canessa CM, Rossier BC, Downey GP.
EMBO J.
1994;
13
(19):
4440-50
-
Cl- regulation of a Ca(2+)-activated nonselective cation channel in beta-agonist-treated fetal distal lung epithelium.
Tohda H,
Foskett JK, O'Brodovich H, Marunaka Y.
Am J Physiol.
1994;
266
(1 Pt 1):
C104-9
-
Endotoxin-stimulated alveolar macrophages impair lung epithelial Na+ transport by an L-Arg-dependent mechanism.
Compeau CG,
Rotstein OD, Tohda H, Marunaka Y, Rafii B, Slutsky AS, O'Brodovich H.
Am J Physiol.
1994;
266
(5 Pt 1):
C1330-41
-
Regional expression of CFTR in developing human respiratory tissues.
Tizzano EF,
O'Brodovich H, Chitayat D, Bènichou JC, Buchwald M.
Am J Respir Cell Mol Biol.
1994;
10
(4):
355-62
-
Thrombin inhibition by fetal distal lung epithelium is different in fetal and adult plasma.
Andrew M,
Berry L, O'Brodovich H.
Am J Respir Cell Mol Biol.
1994;
11
(1):
35-41
-
5-(N-Ethyl-N-isopropyl)amiloride sensitive Na+ currents in intact fetal distal lung epithelial cells.
Wang X,
Kleyman TR, Tohda H, Marunaka Y, O'Brodovich H.
Can J Physiol Pharmacol.
1993;
71
(1):
58-62
-
Activation of Cl- currents by intracellular chloride in fibroblasts stably expressing the human cystic fibrosis transmembrane conductance regulator.
Wang X,
Marunaka Y, Fedorko L, Dho S, Foskett JK, O'Brodovich H.
Can J Physiol Pharmacol.
1993;
71
(9):
645-9
-
Effect of K channel blockers on basal and beta-agonist stimulated ion transport by fetal distal lung epithelium.
O'Brodovich H,
Rafii B.
Can J Physiol Pharmacol.
1993;
71
(1):
54-7
-
Efficacy of albuterol administered by nebulizer versus spacer device in children with acute asthma.
Kerem E,
Levison H, Schuh S, O'Brodovich H, Reisman J, Bentur L, Canny GJ.
J Pediatr.
1993;
123
(2):
313-7
-
Exogenous surfactant rapidly increases PaO2 in mature rabbits with lungs that contain large amounts of saline.
O'Brodovich H,
Hannam V.
Am Rev Respir Dis.
1993;
147
(5):
1087-90
-
Expression of the epithelial Na+ channel in the developing rat lung.
O'Brodovich H,
Canessa C, Ueda J, Rafii B, Rossier BC, Edelson J.
Am J Physiol.
1993;
265
(2 Pt 1):
C491-6
-
Fetal lung epithelial cells contain two populations of amiloride-sensitive Na+ channels.
Matalon S,
Bauer ML, Benos DJ, Kleyman TR, Lin C, Cragoe EJ, O'Brodovich H.
Am J Physiol.
1993;
264
(4 Pt 1):
L357-64
-
Hindlimb and lung lymph flows during prolonged exercise.
Coates G,
O'Brodovich H, Goeree G.
J Appl Physiol.
1993;
75
(2):
633-8
-
Novobiocin forms cation-permeable ion channels in rat fetal distal lung epithelium.
O'Brodovich H,
Wang X, Li C, Rafii B, Correa J, Bear C.
Am J Physiol.
1993;
264
(6 Pt 1):
C1532-7
-
Ontogeny of alpha 1- and beta 1-isoforms of Na(+)-K(+)-ATPase in fetal distal rat lung epithelium.
O'Brodovich H,
Staub O, Rossier BC, Geering K, Kraehenbuhl JP.
Am J Physiol.
1993;
264
(5 Pt 1):
C1137-43
-
Whole-cell Cl- currents in a human peripheral airway epithelial cell line.
Wang X,
Fedorko L, Marunaka Y, O'Brodovich H.
Can J Physiol Pharmacol.
1993;
71
(9):
662-70
-
Analgesia in children with sickle cell crisis: comparison of intermittent opioids vs. continuous intravenous infusion of morphine and placebo-controlled study of oxygen inhalation.
Robieux IC,
Kellner JD, Coppes MJ, Shaw D, Brown E, Good C, O'Brodovich H, Manson D, Olivieri NF, Zipursky A.
Pediatr Hematol Oncol.
1992 Oct-Dec;
9
(4):
317-26
-
Arginine vasopressin and atrial natriuretic peptide do not alter ion transport by cultured fetal distal lung epithelium.
O'Brodovich H,
Rafii B, Perlon P.
Pediatr Res.
1992;
31
(4 Pt 1):
318-22
-
Bicarbonate concentration in rhesus monkey and guinea pig fetal lung liquid.
O'Brodovich H,
Merritt TA.
Am Rev Respir Dis.
1992;
146
(6):
1613-4
-
Cytosolic Ca(2+)-induced modulation of ion selectivity and amiloride sensitivity of a cation channel and beta agonist action in fetal lung epithelium.
Marunaka Y,
Tohda H, Hagiwara N, O'Brodovich H.
Biochem Biophys Res Commun.
1992;
187
(2):
648-56
-
Effects of insulin and tyrosine kinase inhibitor on ion transport in the alveolar cell of the fetal lung.
Hagiwara N,
Tohda H, Doi Y, O'Brodovich H, Marunaka Y.
Biochem Biophys Res Commun.
1992;
187
(2):
802-8
-
Oxygen therapy in sickle cell disease.
Zipursky A,
Robieux IC, Brown EJ, Shaw D, O'Brodovich H, Kellner JD, Coppes MJ, Koren G, Olivieri NF.
Am J Pediatr Hematol Oncol.
1992;
14
(3):
222-8
-
A549 lung epithelial cells synthesize anticoagulant molecules on the cell surface and matrix and in conditioned media.
Berry L,
Andrew M, Post M, Ofosu F, O'Brodovich H.
Am J Respir Cell Mol Biol.
1991;
4
(4):
338-46
-
Bronchopulmonary dysplasia: improvement in lung function between 7 and 10 years of age.
Blayney M,
Kerem E, Whyte H, O'Brodovich H.
J Pediatr.
1991;
118
(2):
201-6
-
Cardiopulmonary function during long-term central venous catheterization.
O'Brodovich H,
Adams M, Coates G, Way RC, Andrew M.
Am J Pediatr Hematol Oncol.
1991;
13
(2):
148-51
-
Cation selective channel in fetal alveolar type II epithelium.
Orser BA,
Bertlik M, Fedorko L, O'Brodovich H.
Biochim Biophys Acta.
1991;
1094
(1):
19-26
-
Epithelial ion transport in the fetal and perinatal lung.
O'Brodovich H,
Am J Physiol.
1991;
261
(4 Pt 1):
C555-64
-
Fatal pulmonary arterial occlusive vascular disease following chemotherapy in a 9-month-old infant.
Bentur L,
Cullinane C, Wilson P, Greenberg M, O'Brodovich H, Silver MM.
Hum Pathol.
1991;
22
(12):
1295-8
-
Influence of fetal pulmonary epithelium on thrombin activity.
O'Brodovich H,
Berry L, D'Costa M, Burrows R, Andrew M.
Am J Physiol.
1991;
261
(4 Pt 1):
L262-70
-
Influence of gestational age on potential difference across fetal type II alveolar epithelium in alveolar-like structures.
Orser B,
Fedorko L, Rafii B, Post M, O'Brodovich H.
Biol Neonate.
1991;
59
(2):
61-8
-
Sodium channel but neither Na(+)-H+ nor Na-glucose symport inhibitors slow neonatal lung water clearance.
O'Brodovich H,
Hannam V, Rafii B.
Am J Respir Cell Mol Biol.
1991;
5
(4):
377-84
-
Amiloride impairs lung water clearance in newborn guinea pigs.
O'Brodovich H,
Hannam V, Seear M, Mullen JB.
J Appl Physiol.
1990;
68
(4):
1758-62
-
Bioelectric properties of fetal alveolar epithelial monolayers.
O'Brodovich H,
Rafii B, Post M.
Am J Physiol.
1990;
258
(4 Pt 1):
L201-6
-
Cation channels in apical membrane of fetal alveolar epithelium.
Orser B,
Bertlik H, Fedorko L, O'Brodovich H.
Can J Anaesth.
1990;
37
(4 Pt 2):
S3
-
Effect of fibrinogen degradation products and lung ground substance on surfactant function.
O'Brodovich HM,
Weitz JI, Possmayer F.
Biol Neonate.
1990;
57
(6):
325-33
-
Effect of pentoxifylline on hemodynamics, alveolar fluid reabsorption, and pulmonary edema in a model of acute lung injury.
Seear MD,
Hannam VL, Kaapa P, Raj JU, O'Brodovich HM.
Am Rev Respir Dis.
1990;
142
(5):
1083-7
-
Sequential pulmonary function measurements during treatment of infantile chronic interstitial pneumonitis.
Kerem E,
Bentur L, England S, Reisman J, O'Brodovich H, Bryan AC, Levison H.
J Pediatr.
1990;
116
(1):
61-7
-
When the alveolus is flooding, it's time to man the pumps.
O'Brodovich H,
Am Rev Respir Dis.
1990;
142
(6 Pt 1):
1247-8
-
Simultaneous measurement of lung clearance rates for Tc- and In-DTPA in normal and damaged lungs.
O'Brodovich H,
Coates G, Kay J, Muysson D.
J Appl Physiol.
1989;
66
(5):
2293-7
-
The response of the pulmonary circulation to exercise during normoxia and hypoxia following pneumonectomy in the adult sheep.
Smith M,
Coates G, Kay JM, O'Brodovich H.
Can J Physiol Pharmacol.
1989;
67
(3):
202-6
-
Airway epithelial damage in premature infants with respiratory failure.
Lee RM,
O'Brodovich H.
Am Rev Respir Dis.
1988;
137
(2):
450-7
-
Angiotensin II prevents hypoxic pulmonary hypertension and vascular changes in rat.
Rabinovitch M,
Mullen M, Rosenberg HC, Maruyama K, O'Brodovich H, Olley PM.
Am J Physiol.
1988;
254
(3 Pt 2):
H500-8
-
Fetal lamb coagulation system during birth asphyxia.
Andrew M,
O'Brodovich H, Mitchell L.
Am J Hematol.
1988;
28
(3):
201-3
-
Fetal lamb coagulation system during normal birth.
Andrew M,
O'Brodovich H, Mitchell L.
Am J Hematol.
1988;
28
(2):
116-8
-
Lung clearance of 99mTc-DTPA in patients with acute lung injury and pulmonary edema.
Coates G,
O'Brodovich H, Dolovich M.
J Thorac Imaging.
1988;
3
(3):
21-7
-
Pulmonary clearance of 99mTc-DTPA in infants who subsequently develop bronchopulmonary dysplasia.
O'Brodovich H,
Coates G.
Am Rev Respir Dis.
1988;
137
(1):
210-2
-
The effect of hypoxia on platelet survival and site of sequestration in the newborn rabbit.
Castle V,
Coates G, Mitchell LG, O'Brodovich H, Andrew M.
Thromb Haemost.
1988;
59
(1):
45-8
-
Assessment of postmortem respiratory ciliary motility and ultrastructure.
Lee RM,
Rossman CM, O'Brodovich H.
Am Rev Respir Dis.
1987;
136
(2):
445-7
-
Extrapulmonary radioactivity in lung permeability measurements.
Coates G,
O'Brodovich H.
J Nucl Med.
1987;
28
(5):
903-6
-
Long-term outcome of preterm infants with respiratory disease.
Saigal S,
O'Brodovich H.
Clin Perinatol.
1987;
14
(3):
635-50
-
Operation Everest II: coagulation system during prolonged decompression to 282 Torr.
Andrew M,
O'Brodovich H, Sutton J.
J Appl Physiol.
1987;
63
(3):
1262-7
-
Pulmonary clearance of 99mTc-DTPA: a noninvasive assessment of epithelial integrity.
O'Brodovich H,
Coates G.
Lung.
1987;
165
(1):
1-16
-
Pulmonary haemodynamics during exercise after low and high doses of acetylsalicylic acid in sheep.
Coates G,
O'Brodovich H, Jefferies AL.
Respiration.
1987;
52
(2):
94-100
-
Ventilation scintigraphy with submicronic radioaerosol as an adjunct in the diagnosis of congenital lobar emphysema.
Loewy J,
O'Brodovich H, Coates G.
J Nucl Med.
1987;
28
(7):
1213-7
-
Aerosol delivery to the rabbit lung with an infant ventilator.
Flavin M,
MacDonald M, Dolovich M, Coates G, O'Brodovich H.
Pediatr Pulmonol.
1986 Jan-Feb;
2
(1):
35-9
-
Effect of exercise on lung lymph flow in unanesthetized sheep with increased pulmonary vascular permeability.
O'Brodovich H,
Coates G.
Am Rev Respir Dis.
1986;
134
(5):
862-6
-
Effect of inspiratory resistance and PEEP on 99mTc-DTPA clearance.
O'Brodovich H,
Coates G, Marrin M.
J Appl Physiol.
1986;
60
(5):
1461-5
-
Effect of isoproterenol or exercise on pulmonary lymph flow and hemodynamics.
O'Brodovich H,
Coates G.
J Appl Physiol.
1986;
60
(1):
38-44
-
Increases in factor VIII complex and fibrinolytic activity are dependent on exercise intensity.
Andrew M,
Carter C, O'Brodovich H, Heigenhauser G.
J Appl Physiol.
1986;
60
(6):
1917-22
-
Measurement of pulmonary epithelial permeability with 99mTc-DTPA aerosol.
Coates G,
O'Brodovich H.
Semin Nucl Med.
1986;
16
(4):
275-84
-
Pulmonary deposition sites of an inhaled radiolabeled submicronic aerosol.
Kay J,
Coates G, O'Brodovich H.
Pediatr Res.
1986;
20
(12):
1297-300
-
The contribution of lymphatic drainage to the clearance of inhaled 99mTc-DTPA from the lungs.
Coates G,
O'Brodovich HM.
Clin Invest Med.
1986;
9
(1):
15-20
-
On pulmonary epithelial permeability.
O'Brodovich H,
Pediatr Pulmonol.
1985 Sep-Oct;
1
(5):
291
-
Bradykinin is degraded in hypoxic lungs and does not affect epithelial permeability.
O'Brodovich H,
Kay J, Coates G.
J Appl Physiol.
1985;
59
(4):
1185-90
-
Bronchopulmonary dysplasia. Unresolved neonatal acute lung injury.
O'Brodovich HM,
Mellins RB.
Am Rev Respir Dis.
1985;
132
(3):
694-709
-
Fluosol-DA causes pulmonary hypertension and increased lung lymph flow in unanesthetized sheep.
O'Brodovich H,
Belbeck L, Andrew M, Coates G.
Clin Invest Med.
1985;
8
(1):
15-21
-
Hypoxia-induced vasopressin release and coagulopathy in a normal subject.
Andrew M,
O'Brodovich H, Coates G, Robertson GL, Gray GW.
Aviat Space Environ Med.
1985;
56
(12):
1220-3
-
Pulmonary thromboemboli after neonatal asphyxia.
Arnold J,
O'Brodovich H, Whyte R, Coates G.
J Pediatr.
1985;
106
(5):
806-9
-
Retraction of two articles: Bradykinin.
Stalcup SA,
Lipset JS, Legant PM, Leuenberger PJ, Pang LM, O'Brodovich HM, Mellins RB.
J Appl Physiol.
1985;
59
(4):
1333
-
Retraction. Bradykinin production and increased pulmonary endothelial permeability during acute respiratory failure in unanesthetized sheep.
O'Brodovich HM,
Stalcup SA, Pang LM, Lipset JS, Mellins RB.
J Clin Invest.
1985;
75
(5):
1747
-
Ciliary defects associated with the development of bronchopulmonary dysplasia. Ciliary motility and ultrastructure.
Lee RM,
Rossman CM, O'Brodovich H, Forrest JB, Newhouse MT.
Am Rev Respir Dis.
1984;
129
(1):
190-3
-
Effects of exercise on lung lymph flow in sheep and goats during normoxia and hypoxia.
Coates G,
O'Brodovich H, Jefferies AL, Gray GW.
J Clin Invest.
1984;
74
(1):
133-41
-
Hypoxia alters blood coagulation during acute decompression in humans.
O'Brodovich HM,
Andrew M, Gray GW, Coates G.
J Appl Physiol.
1984;
56
(3):
666-70
-
Measurement of pulmonary clearance of radioaerosol using a portable sodium iodide probe.
Jefferies AL,
Coates G, Webber CE, O'Brodovich HM.
J Appl Physiol.
1984;
57
(6):
1908-12
-
Plasma catecholamines during hypoxemia and hypercapnia.
O'Brodovich H,
Am J Physiol.
1984;
247
(2 Pt 2):
H341-2
-
Pulmonary epithelial permeability in hyaline-membrane disease.
Jefferies AL,
Coates G, O'Brodovich H.
N Engl J Med.
1984;
311
(17):
1075-80
-
Quantitative ventilation-perfusion lung scans in infants and children: utility of a submicronic radiolabeled aerosol to assess ventilation.
O'Brodovich HM,
Coates G.
J Pediatr.
1984;
105
(3):
377-83
-
Trypan blue method for the identification of areas of damage to airway epithelium due to mechanical trauma.
Lee RM,
Chambers C, O'Brodovich H, Forrest JB.
Scan Electron Microsc.
1984;
(Pt 3):
1267-71
-
Assessment of coagulation cascade during air microembolization of the lung.
O'Brodovich H,
Andrew M, Silver R, Coates G.
J Appl Physiol.
1983;
55
(6):
1743-7
-
Effect of high-frequency oscillation on lung lymph flow.
Jefferies AL,
Hamilton P, O'Brodovich HM.
J Appl Physiol.
1983;
55
(5):
1373-8
-
Noninvasive diagnosis of pulmonary hemorrhage in rheumatoid arthritis.
O'Brodovich HM,
Way RC, Andrew M, Dent PB.
Pediatrics.
1983;
72
(5):
720-3
-
Role of lymphatics in removal of sheep lung surfactant lipid.
Tarpey MM,
O'Brodovich HM, Young SL.
J Appl Physiol.
1983;
54
(4):
984-8
-
Bradykinin-induced increase in pulmonary vascular permeability in hypoxic sheep.
Pang LM,
O'Brodovich HM, Mellins RB, Stalcup SA.
J Appl Physiol.
1982;
52
(2):
370-5
-
Effects of growth on the diffusion constant for carbon monoxide.
O'Brodovich HM,
Mellins RB, Mansell AL.
Am Rev Respir Dis.
1982;
125
(6):
670-3
-
Hemodynamic and vasoactive mediator response to experimental respiratory failure.
O'Brodovich HM,
Stalcup SA, Pang LM, Mellins RB.
J Appl Physiol.
1982;
52
(5):
1230-6
-
Bradykinin production and increased pulmonary endothelial permeability during acute respiratory failure in unanesthetized sheep.
O'Brodovich HM,
Stalcup SA, Pang LM, Lipset JS, Mellins RB.
J Clin Invest.
1981;
67
(2):
514-22
-
Familial lymphoid interstitial pneumonia: a long-term follow-up.
O'Brodovich HM,
Moser MM, Lu L.
Pediatrics.
1980;
65
(3):
523-8
-
Field studies on the use of coated porous polyurethane plugs as indwelling monitors of organochlorine pesticides and polychlorinated biphenyl contents of streams.
Uthe JF,
Reinke J, O'Brodovich H.
Environ Lett.
1974;
6
(2):
103-15
-
Determination of polychlorinated biphenyls in the presence of organochlorine pesticides by thin-layer chromatography.
Reinke J,
Uthe JF, O'Brodovich H.
Environ Lett.
1973;
4
(3):
201-10
Help