Publications
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Nocturia compounds nocturnal wakefulness in older individuals with insomnia.
Zeitzer JM,
Bliwise DL, Hernandez B, Friedman L, Yesavage JA.
J Clin Sleep Med.
2013;
9
(3):
259-62
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Phenotyping apathy in individuals with Alzheimer disease using functional principal component analysis.
Zeitzer JM,
David R, Friedman L, Mulin E, Garcia R, Wang J, Yesavage JA, Robert PH, Shannon W.
Am J Geriatr Psychiatry.
2013;
21
(4):
391-7
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The acute effects of light on murine sleep during the dark phase: importance of melanopsin for maintenance of light-induced sleep.
Muindi F,
Zeitzer JM, Colas D, Heller HC.
Eur J Neurosci.
2013;
37
(11):
1727-36
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Brief morning light treatment for sleep/wake disturbances in older memory-impaired individuals and their caregivers.
Friedman L,
Spira AP, Hernandez B, Mather C, Sheikh J, Ancoli-Israel S, Yesavage JA, Zeitzer JM.
Sleep Med.
2012;
13
(5):
546-9
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Decreased daytime motor activity associated with apathy in Alzheimer disease: an actigraphic study.
David R,
Mulin E, Friedman L, Le Duff F, Cygankiewicz E, Deschaux O, Garcia R, Yesavage JA, Robert PH, Zeitzer JM.
Am J Geriatr Psychiatry.
2012;
20
(9):
806-14
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Modeling caffeine concentrations with the Stanford Caffeine Questionnaire: preliminary evidence for an interaction of chronotype with the effects of caffeine on sleep.
Nova P,
Hernandez B, Ptolemy AS, Zeitzer JM.
Sleep Med.
2012;
13
(4):
362-7
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Modeling the effects of obstructive sleep apnea and hypertension in Vietnam veterans with PTSD.
Kinoshita LM,
Yesavage JA, Noda A, Jo B, Hernandez B, Taylor J, Zeitzer JM, Friedman L, Fairchild JK, Cheng J, Kuschner W, O'Hara R, Holty JE, Scanlon BK.
Sleep Breath.
2012;
16
(4):
1201-9
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Phenotyping Apathy in Individuals With Alzheimer Disease Using Functional Principal Component Analysis.
Zeitzer JM,
David R, Friedman L, Mulin E, Garcia R, Wang J, Yesavage JA, Robert PH, Shannon W.
Am J Geriatr Psychiatry.
2012
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Time-course of cerebrospinal fluid histamine in the wake-consolidated squirrel monkey.
Zeitzer JM,
Kodama T, Buckmaster CL, Honda Y, Lyons DM, Nishino S, Mignot E.
J Sleep Res.
2012;
21
(2):
189-94
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Circadian clock gene polymorphisms and sleep-wake disturbance in Alzheimer disease.
Yesavage JA,
Noda A, Hernandez B, Friedman L, Cheng JJ, Tinklenberg JR, Hallmayer J, O'hara R, David R, Robert P, Landsverk E, Zeitzer JM.
Am J Geriatr Psychiatry.
2011;
19
(7):
635-43
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Effectiveness of evening phototherapy for insomnia is reduced by bright daytime light exposure.
Zeitzer JM,
Friedman L, Yesavage JA.
Sleep Med.
2011;
12
(8):
805-7
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Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans.
Gooley JJ,
Chamberlain K, Smith KA, Khalsa SB, Rajaratnam SM, Van Reen E, Zeitzer JM, Czeisler CA, Lockley SW.
J Clin Endocrinol Metab.
2011;
96
(3):
E463-72
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Faster REM sleep EEG and worse restedness in older insomniacs with HLA DQB1*0602.
Zeitzer JM,
Fisicaro RA, Grove ME, Mignot E, Yesavage JA, Friedman L.
Psychiatry Res.
2011;
187
(3):
397-400
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Initial cognitive performance predicts longitudinal aviator performance.
Yesavage JA,
Jo B, Adamson MM, Kennedy Q, Noda A, Hernandez B, Zeitzer JM, Friedman LF, Fairchild K, Scanlon BK, Murphy GM, Taylor JL.
J Gerontol B Psychol Sci Soc Sci.
2011;
66
(4):
444-53
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Lack of Association Between COMT Polymorphisms and Apathy in Alzheimer's Disease.
David R,
Friedman L, Mulin E, Noda A, Le Duff F, Kennedy Q, Garcia R, Robert PH, Yesavage JA, Zeitzer JM.
J Alzheimers Dis.
2011;
27
(1):
155-61
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Relationship between apathy and sleep disturbance in mild and moderate Alzheimer's disease: an actigraphic study.
Mulin E,
Zeitzer JM, Friedman L, Le Duff F, Yesavage J, Robert PH, David R.
J Alzheimers Dis.
2011;
25
(1):
85-91
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Response of the human circadian system to millisecond flashes of light.
Zeitzer JM,
Ruby NF, Fisicaro RA, Heller HC.
PLoS One.
2011;
6
(7):
e22078
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The roles of COMT val158met status and aviation expertise in flight simulator performance and cognitive ability.
Kennedy Q,
Taylor JL, Noda A, Adamson M, Murphy GM, Zeitzer JM, Yesavage JA.
Behav Genet.
2011;
41
(5):
700-8
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Effects of sleep on the cardiovascular and thermoregulatory systems: a possible role for hypocretins.
Schwimmer H,
Stauss HM, Abboud F, Nishino S, Mignot E, Zeitzer JM.
J Appl Physiol.
2010;
109
(4):
1053-63
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Preliminary evidence that plasma oxytocin levels are elevated in major depression.
Parker KJ,
Kenna HA, Zeitzer JM, Keller J, Blasey CM, Amico JA, Schatzberg AF.
Psychiatry Res.
2010;
178
(2):
359-62
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Sex differences in phase angle of entrainment and melatonin amplitude in humans.
Cain SW,
Dennison CF, Zeitzer JM, Guzik AM, Khalsa SB, Santhi N, Schoen MW, Czeisler CA, Duffy JF.
J Biol Rhythms.
2010;
25
(4):
288-96
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Insomnia in the context of traumatic brain injury.
Zeitzer JM,
Friedman L, O'Hara R.
J Rehabil Res Dev.
2009;
46
(6):
827-36
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Modafinil and γ-hydroxybutyrate have sleep state-specific pharmacological actions on hypocretin-1 physiology in a primate model of human sleep.
Zeitzer JM,
Buckmaster CL, Landolt HP, Lyons DM, Mignot E.
Behav Pharmacol.
2009;
20
(7):
643-52
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Neuropsychiatric diagnosis and management of chronic sequelae of war-related mild to moderate traumatic brain injury.
Halbauer JD,
Ashford JW, Zeitzer JM, Adamson MM, Lew HL, Yesavage JA.
J Rehabil Res Dev.
2009;
46
(6):
757-96
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Scheduled bright light for treatment of insomnia in older adults.
Friedman L,
Zeitzer JM, Kushida C, Zhdanova I, Noda A, Lee T, Schneider B, Guilleminault C, Sheikh J, Yesavage JA.
J Am Geriatr Soc.
2009;
57
(3):
441-52
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Sleep apnea, apolipoprotein epsilon 4 allele, and TBI: mechanism for cognitive dysfunction and development of dementia.
O'Hara R,
Luzon A, Hubbard J, Zeitzer JM.
J Rehabil Res Dev.
2009;
46
(6):
837-50
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CSF hypocretin-1 assessment in sleep and neurological disorders.
Bourgin P,
Zeitzer JM, Mignot E.
Lancet Neurol.
2008;
7
(7):
649-62
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Vagal regulation, cortisol, and sleep disruption in women with metastatic breast cancer.
Palesh O,
Zeitzer JM, Conrad A, Giese-Davis J, Mustian KM, Popek V, Nga K, Spiegel D.
J Clin Sleep Med.
2008;
4
(5):
441-9
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A physiologically based mathematical model of melatonin including ocular light suppression and interactions with the circadian pacemaker.
St Hilaire MA,
Gronfier C, Zeitzer JM, Klerman EB.
J Pineal Res.
2007;
43
(3):
294-304
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Decreased sensitivity to phase-delaying effects of moderate intensity light in older subjects.
Duffy JF,
Zeitzer JM, Czeisler CA.
Neurobiol Aging.
2007;
28
(5):
799-807
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In Alzheimer disease, increased wake fragmentation found in those with lower hypocretin-1.
Friedman LF,
Zeitzer JM, Lin L, Hoff D, Mignot E, Peskind ER, Yesavage JA.
Neurology.
2007;
68
(10):
793-4
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Increasing length of wakefulness and modulation of hypocretin-1 in the wake-consolidated squirrel monkey.
Zeitzer JM,
Buckmaster CL, Lyons DM, Mignot E.
Am J Physiol Regul Integr Comp Physiol.
2007;
293
(4):
R1736-42
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Normal cerebrospinal fluid levels of hypocretin-1 (orexin A) in patients with fibromyalgia syndrome.
Taiwo OB,
Russell IJ, Mignot E, Lin L, Michalek JE, Haynes W, Xiao Y, Zeitzer JM, Larson AA.
Sleep Med.
2007;
8
(3):
260-5
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Plasma melatonin rhythms in young and older humans during sleep, sleep deprivation, and wake.
Zeitzer JM,
Duffy JF, Lockley SW, Dijk DJ, Czeisler CA.
Sleep.
2007;
30
(11):
1437-43
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Preliminary evidence that hippocampal volumes in monkeys predict stress levels of adrenocorticotropic hormone.
Lyons DM,
Parker KJ, Zeitzer JM, Buckmaster CL, Schatzberg AF.
Biol Psychiatry.
2007;
62
(10):
1171-4
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Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy.
Zhang S,
Zeitzer JM, Sakurai T, Nishino S, Mignot E.
J Physiol.
2007;
581
(Pt 2):
649-63
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Extracellular adenosine in the human brain during sleep and sleep deprivation: an in vivo microdialysis study.
Zeitzer JM,
Morales-Villagran A, Maidment NT, Behnke EJ, Ackerson LC, Lopez-Rodriguez F, Fried I, Engel J, Wilson CL.
Sleep.
2006;
29
(4):
455-61
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Reduced sleep efficiency in cervical spinal cord injury; association with abolished night time melatonin secretion.
Scheer FA,
Zeitzer JM, Ayas NT, Brown R, Czeisler CA, Shea SA.
Spinal Cord.
2006;
44
(2):
78-81
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The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions.
Zeitzer JM,
Nishino S, Mignot E.
Trends Pharmacol Sci.
2006;
27
(7):
368-74
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Bilateral oculosympathetic paresis associated with loss of nocturnal melatonin secretion in patients with spinal cord injury.
Zeitzer JM,
Ayas NT, Wu AD, Czeisler CA, Brown R.
J Spinal Cord Med.
2005;
28
(1):
55-9
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Kleine-Levin syndrome: a systematic review of 186 cases in the literature.
Arnulf I,
Zeitzer JM, File J, Farber N, Mignot E.
Brain.
2005;
128
(Pt 12):
2763-76
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Temporal dynamics of late-night photic stimulation of the human circadian timing system.
Zeitzer JM,
Khalsa SB, Boivin DB, Duffy JF, Shanahan TL, Kronauer RE, Czeisler CA.
Am J Physiol Regul Integr Comp Physiol.
2005;
289
(3):
R839-44
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Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release.
Zhang S,
Zeitzer JM, Yoshida Y, Wisor JP, Nishino S, Edgar DM, Mignot E.
Sleep.
2004;
27
(4):
619-27
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Locomotor-dependent and -independent components to hypocretin-1 (orexin A) regulation in sleep-wake consolidating monkeys.
Zeitzer JM,
Buckmaster CL, Lyons DM, Mignot E.
J Physiol.
2004;
557
(Pt 3):
1045-53
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Circadian and homeostatic regulation of hypocretin in a primate model: implications for the consolidation of wakefulness.
Zeitzer JM,
Buckmaster CL, Parker KJ, Hauck CM, Lyons DM, Mignot E.
J Neurosci.
2003;
23
(8):
3555-60
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Diurnal variation of cerebrospinal fluid hypocretin-1 (Orexin-A) levels in control and depressed subjects.
Salomon RM,
Ripley B, Kennedy JS, Johnson B, Schmidt D, Zeitzer JM, Nishino S, Mignot E.
Biol Psychiatry.
2003;
54
(2):
96-104
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Peak of circadian melatonin rhythm occurs later within the sleep of older subjects.
Duffy JF,
Zeitzer JM, Rimmer DW, Klerman EB, Dijk DJ, Czeisler CA.
Am J Physiol Endocrinol Metab.
2002;
282
(2):
E297-303
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Regional analyses of CNS microdialysate glucose and lactate in seizure patients.
Cornford EM,
Shamsa K, Zeitzer JM, Enriquez CM, Wilson CL, Behnke EJ, Fried I, Engel J.
Epilepsia.
2002;
43
(11):
1360-71
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The role of hypocretins (orexins) in sleep regulation and narcolepsy.
Taheri S,
Zeitzer JM, Mignot E.
Annu Rev Neurosci.
2002:
25
283-313
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Ultradian sleep-cycle variation of serotonin in the human lateral ventricle.
Zeitzer JM,
Maidment NT, Behnke EJ, Ackerson LC, Fried I, Engel J, Wilson CL.
Neurology.
2002;
59
(8):
1272-4
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Absence of an increase in the duration of the circadian melatonin secretory episode in totally blind human subjects.
Klerman EB,
Zeitzer JM, Duffy JF, Khalsa SB, Czeisler CA.
J Clin Endocrinol Metab.
2001;
86
(7):
3166-70
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Absence of detectable melatonin and preservation of cortisol and thyrotropin rhythms in tetraplegia.
Zeitzer JM,
Ayas NT, Shea SA, Brown R, Czeisler CA.
J Clin Endocrinol Metab.
2000;
85
(6):
2189-96
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Dose-response relationship for light intensity and ocular and electroencephalographic correlates of human alertness.
Cajochen C,
Zeitzer JM, Czeisler CA, Dijk DJ.
Behav Brain Res.
2000;
115
(1):
75-83
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Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression.
Zeitzer JM,
Dijk DJ, Kronauer R, Brown E, Czeisler C.
J Physiol.
2000:
526 Pt 3
695-702
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Do plasma melatonin concentrations decline with age?
Zeitzer JM,
Daniels JE, Duffy JF, Klerman EB, Shanahan TL, Dijk DJ, Czeisler CA.
Am J Med.
1999;
107
(5):
432-6
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Photopic transduction implicated in human circadian entrainment.
Zeitzer JM,
Kronauer RE, Czeisler CA.
Neurosci Lett.
1997;
232
(3):
135-8
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Resetting the melatonin rhythm with light in humans.
Shanahan TL,
Zeitzer JM, Czeisler CA.
J Biol Rhythms.
1997;
12
(6):
556-67
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