Robert Malenka

Publications

• Molecular dissociation of the role of PSD-95 in regulating synaptic strength and LTD. Xu W, Schlüter OM, Steiner P, Czervionke BL, Sabatini B, Malenka RC. Neuron. 2008; 57 (2): 248-62
• Understanding synapses: past, present, and future. Südhof TC, Malenka RC. Neuron. 2008; 60 (3): 469-76
• Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models. Kreitzer AC, Malenka RC. Nature. 2007; 445 (7128): 643-7
• Synaptic scaling mediated by glial TNF-alpha. Stellwagen D, Malenka RC. Nature. 2006; 440 (7087): 1054-9
• Spike timing-dependent long-term potentiation in ventral tegmental area dopamine cells requires PKC. Luu P, Malenka RC. J Neurophysiol. 2008; 100 (1): 533-8
• Endocytosis and recycling of AMPA receptors lacking GluR2/3. Biou V, Bhattacharyya S, Malenka RC. Proc Natl Acad Sci U S A. 2008; 105 (3): 1038-43
• Mechanisms underlying dedepression of synaptic NMDA receptors in the hippocampus. Morishita W, Malenka RC. J Neurophysiol. 2008; 99 (1): 254-63
• Synaptic plasticity: multiple forms, functions, and mechanisms. Citri A, Malenka RC. Neuropsychopharmacology. 2008; 33 (1): 18-41
• Mechanism and time course of cocaine-induced long-term potentiation in the ventral tegmental area. Argilli E, Sibley DR, Malenka RC, England PM, Bonci A. J Neurosci. 2008; 28 (37): 9092-100
• Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression. Morishita W, Lu W, Smith GB, Nicoll RA, Bear MF, Malenka RC. Neuropharmacology. 2007; 52 (1): 71-6
• Mechanisms for synapse specificity during striatal long-term depression. Singla S, Kreitzer AC, Malenka RC. J Neurosci. 2007; 27 (19): 5260-4
• Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Guzman R, Uchida N, Bliss TM, He D, Christopherson KK, Stellwagen D, Capela A, Greve J, Malenka RC, Moseley ME, Palmer TD, Steinberg GK. Proc Natl Acad Sci U S A. 2007; 104 (24): 10211-6
• Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome. Fernandez F, Morishita W, Zuniga E, Nguyen J, Blank M, Malenka RC, Garner CC. Nat Neurosci. 2007; 10 (4): 411-3
• Alternative N-terminal domains of PSD-95 and SAP97 govern activity-dependent regulation of synaptic AMPA receptor function. Schlüter OM, Xu W, Malenka RC. Neuron. 2006; 51 (1): 99-111
• Transsynaptic signaling by postsynaptic synapse-associated protein 97. Regalado MP, Terry-Lorenzo RT, Waites CL, Garner CC, Malenka RC. J Neurosci. 2006; 26 (8): 2343-57
• CREB modulates excitability of nucleus accumbens neurons. Dong Y, Green T, Saal D, Marie H, Neve R, Nestler EJ, Malenka RC. Nat Neurosci. 2006; 9 (4): 475-7
• Substrate localization creates specificity in calcium/calmodulin-dependent protein kinase II signaling at synapses. Tsui J, Malenka RC. J Biol Chem. 2006; 281 (19): 13794-804
• Neural mechanisms of addiction: the role of reward-related learning and memory. Hyman SE, Malenka RC, Nestler EJ. Annu Rev Neurosci. 2006: 29 565-98
• A schizophrenia-related sensorimotor deficit links alpha 3-containing GABAA receptors to a dopamine hyperfunction. Yee BK, Keist R, von Boehmer L, Studer R, Benke D, Hagenbuch N, Dong Y, Malenka RC, Fritschy JM, Bluethmann H, Feldon J, Möhler H, Rudolph U. Proc Natl Acad Sci U S A. 2005; 102 (47): 17154-9
• GABA excitation in the adult brain: a mechanism for excitation- neurogenesis coupling. Deisseroth K, Malenka RC. Neuron. 2005; 47 (6): 775-7
• Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses. Morishita W, Marie H, Malenka RC. Nat Neurosci. 2005; 8 (8): 1043-50
• Generation of silent synapses by acute in vivo expression of CaMKIV and CREB. Marie H, Morishita W, Yu X, Calakos N, Malenka RC. Neuron. 2005; 45 (5): 741-52
• Dopamine modulation of state-dependent endocannabinoid release and long-term depression in the striatum. Kreitzer AC, Malenka RC. J Neurosci. 2005; 25 (45): 10537-45
• Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release. Calakos N, Schoch S, Südhof TC, Malenka RC. Neuron. 2004; 42 (6): 889-96
• Excitation-neurogenesis coupling in adult neural stem/progenitor cells. Deisseroth K, Singla S, Toda H, Monje M, Palmer TD, Malenka RC. Neuron. 2004; 42 (4): 535-52
• Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors. Ju W, Morishita W, Tsui J, Gaietta G, Deerinck TJ, Adams SR, Garner CC, Tsien RY, Ellisman MH, Malenka RC. Nat Neurosci. 2004; 7 (3): 244-53
• LTP and LTD: an embarrassment of riches. Malenka RC, Bear MF. Neuron. 2004; 44 (1): 5-21
• A developmental switch in the signaling cascades for LTP induction. Yasuda H, Barth AL, Stellwagen D, Malenka RC. Nat Neurosci. 2003; 6 (1): 15-6
• The long-term potential of LTP. Malenka RC, Nat Rev Neurosci. 2003; 4 (11): 923-6
• Beta-catenin is critical for dendritic morphogenesis. Yu X, Malenka RC. Nat Neurosci. 2003; 6 (11): 1169-77
• Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons. Saal D, Dong Y, Bonci A, Malenka RC. Neuron. 2003; 37 (4): 577-82
• Control of synaptic strength by glial TNFalpha. Beattie EC, Stellwagen D, Morishita W, Bresnahan JC, Ha BK, Von Zastrow M, Beattie MS, Malenka RC. Science. 2002; 295 (5563): 2282-5
• RIM1alpha is required for presynaptic long-term potentiation. Castillo PE, Schoch S, Schmitz F, Südhof TC, Malenka RC. Nature. 2002; 415 (6869): 327-30
• Long-term depression in the nucleus accumbens: a neural correlate of behavioral sensitization to cocaine. Thomas MJ, Beurrier C, Bonci A, Malenka RC. Nat Neurosci. 2001; 4 (12): 1217-23
• Regulation of synaptic strength by protein phosphatase 1. Morishita W, Connor JH, Xia H, Quinlan EM, Shenolikar S, Malenka RC. Neuron. 2001; 32 (6): 1133-48
• Long-term potentiation--a decade of progress? Malenka RC, Nicoll RA. Science. 1999; 285 (5435): 1870-4
• Rapid redistribution of glutamate receptors contributes to long-term depression in hippocampal cultures. Carroll RC, Lissin DV, von Zastrow M, Nicoll RA, Malenka RC. Nat Neurosci. 1999; 2 (5): 454-60