John Boothroyd

Publications

• A helical membrane-binding domain targets the Toxoplasma ROP2 family to the parasitophorous vacuole. Reese ML, Boothroyd JC. Traffic. 2009; 10 (10): 1458-70
• Kiss and spit: the dual roles of Toxoplasma rhoptries. Boothroyd JC, Dubremetz JF. Nat Rev Microbiol. 2008; 6 (1): 79-88
• Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue. Saeij JP, Coller S, Boyle JP, Jerome ME, White MW, Boothroyd JC. Nature. 2007; 445 (7125): 324-7
• Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii. Boyle JP, Rajasekar B, Saeij JP, Ajioka JW, Berriman M, Paulsen I, Roos DS, Sibley LD, White MW, Boothroyd JC. Proc Natl Acad Sci U S A. 2006; 103 (27): 10514-9
• Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles. Alexander DL, Mital J, Ward GE, Bradley P, Boothroyd JC. PLoS Pathog. 2005; 1 (2): e17
• Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells. Kafsack BF, Pena JD, Coppens I, Ravindran S, Boothroyd JC, Carruthers VB. Science. 2009; 323 (5913): 530-3
• A pseudouridine synthase homologue is critical to cellular differentiation in Toxoplasma gondii. Anderson MZ, Brewer J, Singh U, Boothroyd JC. Eukaryot Cell. 2009; 8 (3): 398-409
• Expansion of host range as a driving force in the evolution of Toxoplasma. Boothroyd JC, Mem Inst Oswaldo Cruz. 2009; 104 (2): 179-84
• Toxoplasma gondii: 25 years and 25 major advances for the field. Boothroyd JC, Int J Parasitol. 2009; 39 (8): 935-46
• A highly sensitive FRET-based approach reveals secretion of the actin-binding protein toxofilin during Toxoplasma gondii infection. Lodoen MB, Gerke C, Boothroyd JC. Cell Microbiol. 2009
• RNA analysis by biosynthetic tagging using 4-thiouracil and uracil phosphoribosyltransferase. Zeiner GM, Cleary MD, Fouts AE, Meiring CD, Mocarski ES, Boothroyd JC. Methods Mol Biol. 2008: 419 135-46
• Expression quantitative trait locus mapping of toxoplasma genes reveals multiple mechanisms for strain-specific differences in gene expression. Boyle JP, Saeij JP, Harada SY, Ajioka JW, Boothroyd JC. Eukaryot Cell. 2008; 7 (8): 1403-14
• The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4. Dunn JD, Ravindran S, Kim SK, Boothroyd JC. Infect Immun. 2008; 76 (12): 5853-61
• Secretion of proteins into host cells by Apicomplexan parasites. Ravindran S, Boothroyd JC. Traffic. 2008; 9 (5): 647-56
• A cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence. Saeij JP, Arrizabalaga G, Boothroyd JC. Infect Immun. 2008; 76 (6): 2402-10
• Pulling together: an integrated model of Toxoplasma cell invasion. Carruthers V, Boothroyd JC. Curr Opin Microbiol. 2007; 10 (1): 83-9
• Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors. Vyas A, Kim SK, Giacomini N, Boothroyd JC, Sapolsky RM. Proc Natl Acad Sci U S A. 2007; 104 (15): 6442-7
• Toxoplasma gondii dysregulates IFN-gamma-inducible gene expression in human fibroblasts: insights from a genome-wide transcriptional profiling. Kim SK, Fouts AE, Boothroyd JC. J Immunol. 2007; 178 (8): 5154-65
• The BSR4 protein is up-regulated in Toxoplasma gondii bradyzoites, however the dominant surface antigen recognised by the P36 monoclonal antibody is SRS9. Van TT, Kim SK, Camps M, Boothroyd JC, Knoll LJ. Int J Parasitol. 2007; 37 (8-9): 877-85
• Toxoplasma gondii: inconsistent dissemination patterns following oral infection in mice. Boyle JP, Saeij JP, Boothroyd JC. Exp Parasitol. 2007; 116 (3): 302-5
• Bradyzoite-specific surface antigen SRS9 plays a role in maintaining Toxoplasma gondii persistence in the brain and in host control of parasite replication in the intestine. Kim SK, Karasov A, Boothroyd JC. Infect Immun. 2007; 75 (4): 1626-34
• Toxoplasma gondii targets a protein phosphatase 2C to the nuclei of infected host cells. Gilbert LA, Ravindran S, Turetzky JM, Boothroyd JC, Bradley PJ. Eukaryot Cell. 2007; 6 (1): 73-83
• Infection with Toxoplasma gondii bradyzoites has a diminished impact on host transcript levels relative to tachyzoite infection. Fouts AE, Boothroyd JC. Infect Immun. 2007; 75 (2): 634-42
• Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space. Coppens I, Dunn JD, Romano JD, Pypaert M, Zhang H, Boothroyd JC, Joiner KA. Cell. 2006; 125 (2): 261-74
• Polymorphic secreted kinases are key virulence factors in toxoplasmosis. Saeij JP, Boyle JP, Coller S, Taylor S, Sibley LD, Brooke-Powell ET, Ajioka JW, Boothroyd JC. Science. 2006; 314 (5806): 1780-3
• Analysis of gene expression during development: lessons from the Apicomplexa. Boyle JP, Saeij JP, Cleary MD, Boothroyd JC. Microbes Infect. 2006; 8 (6): 1623-30
• Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii. Alexander DL, Arastu-Kapur S, Dubremetz JF, Boothroyd JC. Eukaryot Cell. 2006; 5 (7): 1169-73
• Biosynthetic labeling of RNA with uracil phosphoribosyltransferase allows cell-specific microarray analysis of mRNA synthesis and decay. Cleary MD, Meiering CD, Jan E, Guymon R, Boothroyd JC. Nat Biotechnol. 2005; 23 (2): 232-7
• Disruption of a locus encoding a nucleolar zinc finger protein decreases tachyzoite-to-bradyzoite differentiation in Toxoplasma gondii. Vanchinathan P, Brewer JL, Harb OS, Boothroyd JC, Singh U. Infect Immun. 2005; 73 (10): 6680-8
• Identification and disruption of a rhoptry-localized homologue of sodium hydrogen exchangers in Toxoplasma gondii. Karasov AO, Boothroyd JC, Arrizabalaga G. Int J Parasitol. 2005; 35 (3): 285-91
• Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains. Saeij JP, Boyle JP, Grigg ME, Arrizabalaga G, Boothroyd JC. Infect Immun. 2005; 73 (2): 695-702
• A novel rhoptry protein in Toxoplasma gondii bradyzoites and merozoites. Schwarz JA, Fouts AE, Cummings CA, Ferguson DJ, Boothroyd JC. Mol Biochem Parasitol. 2005; 144 (2): 159-66
• Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host. Saeij JP, Boyle JP, Boothroyd JC. Trends Parasitol. 2005; 21 (10): 476-81
• Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. Bradley PJ, Ward C, Cheng SJ, Alexander DL, Coller S, Coombs GH, Dunn JD, Ferguson DJ, Sanderson SJ, Wastling JM, Boothroyd JC. J Biol Chem. 2005; 280 (40): 34245-58
• Stage-specific expression of surface antigens by Toxoplasma gondii as a mechanism to facilitate parasite persistence. Kim SK, Boothroyd JC. J Immunol. 2005; 174 (12): 8038-48
• Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii. Khan A, Taylor S, Su C, Mackey AJ, Boyle J, Cole R, Glover D, Tang K, Paulsen IT, Berriman M, Boothroyd JC, Pfefferkorn ER, Dubey JP, Ajioka JW, Roos DS, Wootton JC, Sibley LD. Nucleic Acids Res. 2005; 33 (9): 2980-92
• The induction of acute ileitis by a single microbial antigen of Toxoplasma gondii. Rachinel N, Buzoni-Gatel D, Dutta C, Mennechet FJ, Luangsay S, Minns LA, Grigg ME, Tomavo S, Boothroyd JC, Kasper LH. J Immunol. 2004; 173 (4): 2725-35
• A GFP-based motif-trap reveals a novel mechanism of targeting for the Toxoplasma ROP4 protein. Bradley PJ, Li N, Boothroyd JC. Mol Biochem Parasitol. 2004; 137 (1): 111-20
• An unusual genotype of Toxoplasma gondii is common in California sea otters (Enhydra lutris nereis) and is a cause of mortality. Miller MA, Grigg ME, Kreuder C, James ER, Melli AC, Crosbie PR, Jessup DA, Boothroyd JC, Brownstein D, Conrad PA. Int J Parasitol. 2004; 34 (3): 275-84
• Role of calcium during Toxoplasma gondii invasion and egress. Arrizabalaga G, Boothroyd JC. Int J Parasitol. 2004; 34 (3): 361-8
• Ionophore-resistant mutant of Toxoplasma gondii reveals involvement of a sodium/hydrogen exchanger in calcium regulation. Arrizabalaga G, Ruiz F, Moreno S, Boothroyd JC. J Cell Biol. 2004; 165 (5): 653-62
• DNA microarrays in parasitology: strengths and limitations. Boothroyd JC, Blader I, Cleary M, Singh U. Trends Parasitol. 2003; 19 (10): 470-6
• Serotyping of Toxoplasma gondii infections in humans using synthetic peptides. Kong JT, Grigg ME, Uyetake L, Parmley S, Boothroyd JC. J Infect Dis. 2003; 187 (9): 1484-95
• Unprocessed Toxoplasma ROP1 is effectively targeted and secreted into the nascent parasitophorous vacuole. Bradley PJ, Hsieh CL, Boothroyd JC. Mol Biochem Parasitol. 2002 Nov-Dec; 125 (1-2): 189-93
• Genetic analysis of tachyzoite to bradyzoite differentiation mutants in Toxoplasma gondii reveals a hierarchy of gene induction. Singh U, Brewer JL, Boothroyd JC. Mol Microbiol. 2002; 44 (3): 721-33
• Structure of the immunodominant surface antigen from the Toxoplasma gondii SRS superfamily. He XL, Grigg ME, Boothroyd JC, Garcia KC. Nat Struct Biol. 2002; 9 (8): 606-11
• Population biology of Toxoplasma gondii and its relevance to human infection: do different strains cause different disease? Boothroyd JC, Grigg ME. Curr Opin Microbiol. 2002; 5 (4): 438-42
• Toxoplasma gondii asexual development: identification of developmentally regulated genes and distinct patterns of gene expression. Cleary MD, Singh U, Blader IJ, Brewer JL, Boothroyd JC. Eukaryot Cell. 2002; 1 (3): 329-40
• Immediate/early response to Trypanosoma cruzi infection involves minimal modulation of host cell transcription. Vaena de Avalos S, Blader IJ, Fisher M, Boothroyd JC, Burleigh BA. J Biol Chem. 2002; 277 (1): 639-44
• An rRNA mutation identifies the apicoplast as the target for clindamycin in Toxoplasma gondii. Camps M, Arrizabalaga G, Boothroyd J. Mol Microbiol. 2002; 43 (5): 1309-18
• Success and virulence in the AIDS pathogen Toxoplasma as the result of sexual recombination between two distinct ancestries Grigg ME, Suzuki Y, Boothroyd JC. Science. 2001: 294 161-16
• Rapid identification of virulent type I strains of the protozoan pathogen Toxoplasma gondii by PCR-restriction fragment length polymorphism analysis at the B1 gene. Grigg ME, Boothroyd JC. J Clin Microbiol. 2001; 39 (1): 398-400
• Isolation and characterization of a cold-sensitive attachment/invasion mutant of Toxoplasma gondii. Uyetake L, Ortega-Barria E, Boothroyd JC. Exp Parasitol. 2001; 97 (1): 55-9
• Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cells. Blader IJ, Manger ID, Boothroyd JC. J Biol Chem. 2001; 276 (26): 24223-31
• Adaptation of signature-tagged mutagenesis for Toxoplasma gondii: a negative screening strategy to isolate genes that are essential in restrictive growth conditions. Knoll LJ, Furie GL, Boothroyd JC. Mol Biochem Parasitol. 2001; 116 (1): 11-6
• Unusual abundance of atypical strains associated with human ocular toxoplasmosis. Grigg ME, Ganatra J, Boothroyd JC, Margolis TP. J Infect Dis. 2001; 184 (5): 633-9
• Resistance as a tool in the study of old and new drug targets in Toxoplasma. McFadden DC, Camps M, Boothroyd JC. Drug Resist Updat. 2001; 4 (2): 79-84
• The pro region of Toxoplasma ROP1 is a rhoptry-targeting signal. Bradley PJ, Boothroyd JC. Int J Parasitol. 2001; 31 (11): 1177-86
• Targeted disruption of an essential RNA-binding protein perturbs cell division in Trypanosoma brucei. Manger ID, Boothroyd JC. Mol Biochem Parasitol. 2001; 116 (2): 239-45
• Toxoplasma gondii: selective killing of extracellular parasites by oxidation using pyrrolidine dithiocarbamate. Camps M, Boothroyd JC. Exp Parasitol. 2001; 98 (4): 206-14
• Surface antigens of Toxoplasma gondii: variations on a theme. Lekutis C, Ferguson DJ, Grigg ME, Camps M, Boothroyd JC. Int J Parasitol. 2001; 31 (12): 1285-92
• Success and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries. Grigg ME, Bonnefoy S, Hehl AB, Suzuki Y, Boothroyd JC. Science. 2001; 294 (5540): 161-5
• Characterization of cytochrome b from Toxoplasma gondii and Q(o) domain mutations as a mechanism of atovaquone-resistance. McFadden DC, Tomavo S, Berry EA, Boothroyd JC. Mol Biochem Parasitol. 2000; 108 (1): 1-12
• Lytic cycle of Toxoplasma gondii. Black MW, Boothroyd JC. Microbiol Mol Biol Rev. 2000; 64 (3): 607-23
• Ionophore-resistant mutants of Toxoplasma gondii reveal host cell permeabilization as an early event in egress. Black MW, Arrizabalaga G, Boothroyd JC. Mol Cell Biol. 2000; 20 (24): 9399-408
• Toxoplasma gondii homologue of plasmodium apical membrane antigen 1 is involved in invasion of host cells. Hehl AB, Lekutis C, Grigg ME, Bradley PJ, Dubremetz JF, Ortega-Barria E, Boothroyd JC. Infect Immun. 2000; 68 (12): 7078-86
• The trans-spliced L30 ribosomal protein mRNA of Trypanosoma brucei is not subject to autogenous feedback control at the messenger RNA level. Wilson K, Uyetake L, Boothroyd JC. Mol Biochem Parasitol. 2000; 111 (1): 199-205
• Toxoplasma gondii: identification of a developmentally regulated family of genes related to SAG2. Lekutis C, Ferguson DJ, Boothroyd JC. Exp Parasitol. 2000; 96 (2): 89-96
• Cytochrome b mutation identified in a decoquinate-resistant mutant of Toxoplasma gondii. McFadden DC, Boothroyd JC. J Eukaryot Microbiol. 1999 Sep-Oct; 46 (5): 81S-82S
• Identification of the pro-mature processing site of Toxoplasma ROP1 by mass spectrometry. Bradley PJ, Boothroyd JC. Mol Biochem Parasitol. 1999; 100 (1): 103-9
• Trypanosoma brucei: cis-acting sequences involved in the developmental regulation of PARP expression. Wilson K, Uyetake L, Boothroyd J. Exp Parasitol. 1999; 91 (3): 222-30
• A Toxoplasma lectin-like activity specific for sulfated polysaccharides is involved in host cell infection. Ortega-Barria E, Boothroyd JC. J Biol Chem. 1999; 274 (3): 1267-76
• The surface of Toxoplasma tachyzoites is dominated by a family of glycosylphosphatidylinositol-anchored antigens related to SAG1. Manger ID, Hehl AB, Boothroyd JC. Infect Immun. 1998; 66 (5): 2237-44
• Processing of Toxoplasma ROP1 protein in nascent rhoptries. Soldati D, Lassen A, Dubremetz JF, Boothroyd JC. Mol Biochem Parasitol. 1998; 96 (1-2): 37-48
• Molecular Biology's Lessons about Toxoplasma Development: Stage-specific Homologs. Knoll LJ, Boothroyd JC. Parasitol Today. 1998; 14 (12): 490-3
• Gene discovery by EST sequencing in Toxoplasma gondii reveals sequences restricted to the Apicomplexa. Ajioka JW, Boothroyd JC, Brunk BP, Hehl A, Hillier L, Manger ID, Marra M, Overton GC, Roos DS, Wan KL, Waterston R, Sibley LD. Genome Res. 1998; 8 (1): 18-28
• Analysis of Toxoplasma gondii stably transfected with a transmembrane variant of its major surface protein, SAG1. Seeber F, Dubremetz JF, Boothroyd JC. J Cell Sci. 1998: 111 ( Pt 1) 23-9
• Expressed sequence tag analysis of the bradyzoite stage of Toxoplasma gondii: identification of developmentally regulated genes. Manger ID, Hehl A, Parmley S, Sibley LD, Marra M, Hillier L, Waterston R, Boothroyd JC. Infect Immun. 1998; 66 (4): 1632-7
• The surface of Toxoplasma: more and less. Boothroyd JC, Hehl A, Knoll LJ, Manger ID. Int J Parasitol. 1998; 28 (1): 3-9
• Development of a stable episomal shuttle vector for Toxoplasma gondii. Black MW, Boothroyd JC. J Biol Chem. 1998; 273 (7): 3972-9
• Isolation of developmentally regulated genes from Toxoplasma gondii by a gene trap with the positive and negative selectable marker hypoxanthine-xanthine-guanine phosphoribosyltransferase. Knoll LJ, Boothroyd JC. Mol Cell Biol. 1998; 18 (2): 807-14
• Identification of a nuclear protein in Trypanosoma brucei with homology to RNA-binding proteins from cis-splicing systems. Manger ID, Boothroyd JC. Mol Biochem Parasitol. 1998; 97 (1-2): 1-11
• Genetic analysis in Toxoplasma: gene discovery with expressed sequence tags and rapid mapping of natural polymorphisms. Hehl A, Manger ID, Boothroyd JC. Methods. 1997; 13 (2): 89-102
• Identification and characterization of SRS1, a Toxoplasma gondii surface antigen upstream of and related to SAG1. Hehl A, Krieger T, Boothroyd JC. Mol Biochem Parasitol. 1997; 89 (2): 271-82
• Genetic and biochemical analysis of development in Toxoplasma gondii. Boothroyd JC, Black M, Bonnefoy S, Hehl A, Knoll LJ, Manger ID, Ortega-Barria E, Tomavo S. Philos Trans R Soc Lond B Biol Sci. 1997; 352 (1359): 1347-54
• Use of Toxoplasma gondii expressing beta-galactosidase for colorimetric assessment of drug activity in vitro. McFadden DC, Seeber F, Boothroyd JC. Antimicrob Agents Chemother. 1997; 41 (9): 1849-53
• Implications of conserved structural motifs in disparate trypanosome surface proteins. Carrington M, Boothroyd J. Mol Biochem Parasitol. 1996; 81 (2): 119-26
• Sequence divergence in a family of variant surface glycoprotein genes from trypanosomes: coding region hypervariability and downstream recombinogenic repeats. Field MC, Boothroyd JC. J Mol Evol. 1996; 42 (5): 500-11
• Use of chimeric recombinant polypeptides to analyse conformational, surface epitopes on trypanosome variant surface glycoproteins. Hsia R, Beals T, Boothroyd JC. Mol Microbiol. 1996; 19 (1): 53-63
• Escherichia coli beta-galactosidase as an in vitro and in vivo reporter enzyme and stable transfection marker in the intracellular protozoan parasite Toxoplasma gondii. Seeber F, Boothroyd JC. Gene. 1996; 169 (1): 39-45
• Restriction enzyme-mediated integration elevates transformation frequency and enables co-transfection of Toxoplasma gondii. Black M, Seeber F, Soldati D, Kim K, Boothroyd JC. Mol Biochem Parasitol. 1995; 74 (1): 55-63
• A homologue of the nuclear GTPase ran/TC4 from Trypanosoma brucei. Field MC, Field H, Boothroyd JC. Mol Biochem Parasitol. 1995; 69 (1): 131-4
• Toxoplasma gondii: stable complementation of sag1 (p30) mutants using SAG1 transfection and fluorescence-activated cell sorting. Kim K, Boothroyd JC. Exp Parasitol. 1995; 80 (1): 46-53
• Trypanosoma brucei: molecular cloning of homologues of small GTP-binding proteins involved in vesicle trafficking. Field MC, Boothroyd JC. Exp Parasitol. 1995; 81 (3): 313-20
• Interconnection between organellar functions, development and drug resistance in the protozoan parasite, Toxoplasma gondii. Tomavo S, Boothroyd JC. Int J Parasitol. 1995; 25 (11): 1293-9
• A selector of transcription initiation in the protozoan parasite Toxoplasma gondii. Soldati D, Boothroyd JC. Mol Cell Biol. 1995; 15 (1): 87-93
• Complementation of a Toxoplasma gondii ROP1 knock-out mutant using phleomycin selection. Soldati D, Kim K, Kampmeier J, Dubremetz JF, Boothroyd JC. Mol Biochem Parasitol. 1995; 74 (1): 87-97
• Toxoplasma workshop overview. Schwartzman JD, Boothroyd JC, Kasper LH. J Eukaryot Microbiol. 1994 Sep-Oct; 41 (5): 19S-21S
• Conformationally appropriate expression of the Toxoplasma antigen SAG1 (p30) in CHO cells. Kim K, Bülow R, Kampmeier J, Boothroyd JC. Infect Immun. 1994; 62 (1): 203-9
• Population biology of Toxoplasma gondii. Boothroyd JC, Sibley LD. Res Immunol. 1993; 144 (1): 14-6
• Development of genetic systems for Toxoplasma gondii. Sibley LD, Pfefferkorn ER, Boothroyd JC. Parasitol Today. 1993; 9 (10): 392-5
• Expression of Toxoplasma gondii P30 as fusions with glutathione S-transferase in animal cells by Sindbis recombinant virus. Xiong C, Grieve RB, Kim K, Boothroyd JC. Mol Biochem Parasitol. 1993; 61 (1): 143-8
• Gene replacement in Toxoplasma gondii with chloramphenicol acetyltransferase as selectable marker. Kim K, Soldati D, Boothroyd JC. Science. 1993; 262 (5135): 911-4
• Molecular cloning and cellular localization of a BiP homologue in Trypanosoma brucei. Divergent ER retention signals in a lower eukaryote. Bangs JD, Uyetake L, Brickman MJ, Balber AE, Boothroyd JC. J Cell Sci. 1993: 105 ( Pt 4) 1101-13
• Population biology of Toxoplasma: clonality, virulence, and speciation (or not). Boothroyd JC, Infect Agents Dis. 1993; 2 (2): 100-2
• Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii. Soldati D, Boothroyd JC. Science. 1993; 260 (5106): 349-52
• Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Sibley LD, Boothroyd JC. Nature. 1992; 359 (6390): 82-5
• Generation of a restriction fragment length polymorphism linkage map for Toxoplasma gondii. Sibley LD, LeBlanc AJ, Pfefferkorn ER, Boothroyd JC. Genetics. 1992; 132 (4): 1003-15
• Antigen-specific (p30) mouse CD8+ T cells are cytotoxic against Toxoplasma gondii-infected peritoneal macrophages. Kasper LH, Khan IA, Ely KH, Buelow R, Boothroyd JC. J Immunol. 1992; 148 (5): 1493-8
• A Toxoplasma gondii rhoptry protein associated with host cell penetration has unusual charge asymmetry. Ossorio PN, Schwartzman JD, Boothroyd JC. Mol Biochem Parasitol. 1992; 50 (1): 1-15
• Construction of a molecular karyotype for Toxoplasma gondii. Sibley LD, Boothroyd JC. Mol Biochem Parasitol. 1992; 51 (2): 291-300
• Genomic organization and context of a trypanosome variant surface glycoprotein gene family. Beals TP, Boothroyd JC. J Mol Biol. 1992; 225 (4): 961-71
• Sequence divergence among members of a trypanosome variant surface glycoprotein gene family. Beals TP, Boothroyd JC. J Mol Biol. 1992; 225 (4): 973-83
• Genes that allow yeast cells to grow in the absence of the HDEL receptor. Hardwick KG, Boothroyd JC, Rudner AD, Pelham HR. EMBO J. 1992; 11 (11): 4187-95
• Mass spectrometry of mRNA cap 4 from trypanosomatids reveals two novel nucleosides. Bangs JD, Crain PF, Hashizume T, McCloskey JA, Boothroyd JC. J Biol Chem. 1992; 267 (14): 9805-15
• Inhibition of protein synthesis results in super-induction of procyclin (PARP) RNA levels. Dorn PL, Aman RA, Boothroyd JC. Mol Biochem Parasitol. 1991; 44 (1): 133-9
• Proposal for a uniform genetic nomenclature in Toxoplasma gondii. Sibley LD, Pfefferkorn ER, Boothroyd JC. Parasitol Today. 1991; 7 (12): 327-8
• Mitochondrial-like DNA sequences flanked by direct and inverted repeats in the nuclear genome of Toxoplasma gondii. Ossorio PN, Sibley LD, Boothroyd JC. J Mol Biol. 1991; 222 (3): 525-36
• Protection of mice from fatal Toxoplasma gondii infection by immunization with p30 antigen in liposomes. Bülow R, Boothroyd JC. J Immunol. 1991; 147 (10): 3496-500
• Lack of introns in the ribosomal protein gene S14 of trypanosomes. Perelman D, Boothroyd JC. Mol Cell Biol. 1990; 10 (6): 3284-8
• Rapid prenatal diagnosis of congenital Toxoplasma infection by using polymerase chain reaction and amniotic fluid. Grover CM, Thulliez P, Remington JS, Boothroyd JC. J Clin Microbiol. 1990; 28 (10): 2297-301
• An expression-site-associated gene family of trypanosomes is expressed in vivo and shows homology to a variant surface glycoprotein gene. Hobbs MR, Boothroyd JC. Mol Biochem Parasitol. 1990; 43 (1): 1-16
• Heat-shock disruption of trans-splicing in trypanosomes: effect on Hsp70, Hsp85 and tubulin mRNA synthesis. Muhich ML, Hsu MP, Boothroyd JC. Gene. 1989; 82 (1): 169-75
• Synthesis of trypanosome hsp70 mRNA is resistant to disruption of trans-splicing by heat shock. Muhich ML, Boothroyd JC. J Biol Chem. 1989; 264 (13): 7107-10
• Cloning of cDNAs encoding a 28 kilodalton antigen of Toxoplasma gondii. Prince JB, Araujo FG, Remington JS, Burg JL, Boothroyd JC, Sharma SD. Mol Biochem Parasitol. 1989; 34 (1): 3-13
• Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by polymerase chain reaction. Burg JL, Grover CM, Pouletty P, Boothroyd JC. J Clin Microbiol. 1989; 27 (8): 1787-92
• The major surface antigen, P30, of Toxoplasma gondii is anchored by a glycolipid. Nagel SD, Boothroyd JC. J Biol Chem. 1989; 264 (10): 5569-74
• A developmentally regulated gene of trypanosomes encodes a homologue of rat protein-disulfide isomerase and phosphoinositol-phospholipase C. Hsu MP, Muhich ML, Boothroyd JC. Biochemistry. 1989; 28 (15): 6440-6
• The alpha- and beta-tubulins of Toxoplasma gondii are encoded by single copy genes containing multiple introns. Nagel SD, Boothroyd JC. Mol Biochem Parasitol. 1988; 29 (2-3): 261-73
• The cap of both miniexon-derived RNA and mRNA of trypanosomes is 7-methylguanosine. Sutton RE, Boothroyd JC. Mol Cell Biol. 1988; 8 (1): 494-6
• Trypanosome trans-splicing utilizes 2'-5' branches and a corresponding debranching activity. Sutton RE, Boothroyd JC. EMBO J. 1988; 7 (5): 1431-7
• Polycistronic transcripts in trypanosomes and their accumulation during heat shock: evidence for a precursor role in mRNA synthesis. Muhich ML, Boothroyd JC. Mol Cell Biol. 1988; 8 (9): 3837-46
• Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii. Burg JL, Perelman D, Kasper LH, Ware PL, Boothroyd JC. J Immunol. 1988; 141 (10): 3584-91
• Precise identification of cleavage sites involved in the unusual processing of trypanosome ribosomal RNA. Campbell DA, Kubo K, Clark CG, Boothroyd JC. J Mol Biol. 1987; 196 (1): 113-24
• An unusually compact ribosomal DNA repeat in the protozoan Giardia lamblia. Boothroyd JC, Wang A, Campbell DA, Wang CC. Nucleic Acids Res. 1987; 15 (10): 4065-84
• Evidence for trans splicing in trypanosomes. Sutton RE, Boothroyd JC. Cell. 1986; 47 (4): 527-35
• Antigenic variation in African trypanosomes. Boothroyd JC, Annu Rev Microbiol. 1985: 39 475-502
• Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes. Campbell DA, Thornton DA, Boothroyd JC. Nature. 1984 Sep 27-Oct 3; 311 (5984): 350-5
• The 5'-limit of transposition and upstream barren region of a trypanosome VSG gene: tandem 76 base-pair repeats flanking (TAA)90. Campbell DA, van Bree MP, Boothroyd JC. Nucleic Acids Res. 1984; 12 (6): 2759-74
• Comparison of the amino acid sequence of the major immunogen from three serotypes of foot and mouth disease virus. Makoff AJ, Paynter CA, Rowlands DJ, Boothroyd JC. Nucleic Acids Res. 1982; 10 (24): 8285-95
• Complete nucleotide sequence of complementary DNA coding for a variant surface glycoprotein from Trypanosoma brucei. Boothroyd JC, Paynter CA, Coleman SL, Cross GA. J Mol Biol. 1982; 157 (3): 547-56
• The nucleotide sequence of cDNA coding for the structural proteins of foot-and-mouth disease virus. Boothroyd JC, Harris TJ, Rowlands DJ, Lowe PA. Gene. 1982; 17 (2): 153-61
• Transcripts coding for variant surface glycoproteins of Trypanosoma brucei have a short, identical exon at their 5' end. Boothroyd JC, Cross GA. Gene. 1982; 20 (2): 281-9
• Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3' end. Bernards A, Van der Ploeg LH, Frasch AC, Borst P, Boothroyd JC, Coleman S, Cross GA. Cell. 1981; 27 (3 Pt 2): 497-505
• Homologous 3'-terminal regions of mRNAs for surface antigens of different antigenic variants of Trypanosoma brucei. Majumder HK, Boothroyd JC, Weber H. Nucleic Acids Res. 1981; 9 (18): 4745-53
• Molecular cloning of foot and mouth disease virus genome and nucleotide sequences in the structural protein genes. Boothroyd JC, Highfield PE, Cross GA, Rowlands DJ, Lowe PA, Brown F, Harris TJ. Nature. 1981; 290 (5809): 800-2
• Variant surface glycoproteins of Trypanosoma brucei are synthesised with cleavable hydrophobic sequences at the carboxy and amino termini. Boothroyd JC, Paynter CA, Cross GA, Bernards A, Borst P. Nucleic Acids Res. 1981; 9 (18): 4735-43
• A variant surface glycoprotein of Trypanosoma brucei synthesized with a C-terminal hydrophobic 'tail' absent from purified glycoprotein. Boothroyd JC, Cross GA, Hoeijmakers JH, Borst P. Nature. 1980; 288 (5791): 624-6
• An introduction to antigenic variation in trypanosomes. Cross GA, Holder AA, Allen G, Boothroyd JC. Am J Trop Med Hyg. 1980; 29 (5 Suppl): 1027-32
• New genes and promoters suggested by the DNA sequence near the end of the coliphage T7 early operon. Boothroyd JC, Hayward RS. Nucleic Acids Res. 1979; 7 (7): 1931-43
• Synchronous Growth and Plastid Replication in the Naturally Wall-less Alga Olisthodiscus luteus. Cattolico RA, Boothroyd JC, Gibbs SP. Plant Physiol. 1976; 57 (4): 497-503