Pehr Harbury

Publications

• Structural ensemble and microscopic elasticity of freely diffusing DNA by direct measurement of fluctuations. Shi X, Herschlag D, Harbury PA. Proc Natl Acad Sci U S A. 2013; 110 (16): E1444-51
• Highly parallel translation of DNA sequences into small molecules. Weisinger RM, Wrenn SJ, Harbury PB. PLoS One. 2012; 7 (3): e28056
• Mesofluidic devices for DNA-programmed combinatorial chemistry. Weisinger RM, Marinelli RJ, Wrenn SJ, Harbury PB. PLoS One. 2012; 7 (3): e32299
• Expedient synthesis of a modular phosphate affinity reagent. Tilmans NP, Krusemark CJ, Harbury PA. Bioconjug Chem. 2010; 21 (6): 1010-3
• Response to comment on remeasuring the double helix Matthew-Fenn RS, Das R, Fenn TD, Schneiders M, Harbury PA. Science. 2009; 325 (5940): 538-540
• A molecular ruler for measuring quantitative distance distributions. Mathew-Fenn RS, Das R, Silverman JA, Walker PA, Harbury PA. PLoS One. 2008; 3 (10): e3229
• Design of protein-ligand binding based on the molecular-mechanics energy model. Boas FE, Harbury PB. J Mol Biol. 2008; 380 (2): 415-24
• Remeasuring the double helix. Mathew-Fenn RS, Das R, Harbury PA. Science. 2008; 322 (5900): 446-9
• Accurate, conformation-dependent predictions of solvent effects on protein ionization constants. Barth P, Alber T, Harbury PB. Proc Natl Acad Sci U S A. 2007; 104 (12): 4898-903
• Chemical evolution as a tool for molecular discovery. Wrenn SJ, Harbury PB. Annu Rev Biochem. 2007: 76 331-49
• Potential energy functions for protein design. Boas FE, Harbury PB. Curr Opin Struct Biol. 2007; 17 (2): 199-204
• Synthetic ligands discovered by in vitro selection. Wrenn SJ, Weisinger RM, Halpin DR, Harbury PB. J Am Chem Soc. 2007; 129 (43): 13137-43
• Misincorporation proton-alkyl exchange (MPAX): engineering cysteine probes into proteins. Burguete AS, Harbury PB, Pfeffer SR. Curr Protoc Protein Sci. 2005: Chapter 26 Unit26.1
• DNA display I. Sequence-encoded routing of DNA populations. Halpin DR, Harbury PB. PLoS Biol. 2004; 2 (7): E173
• DNA display II. Genetic manipulation of combinatorial chemistry libraries for small-molecule evolution. Halpin DR, Harbury PB. PLoS Biol. 2004; 2 (7): E174
• DNA display III. Solid-phase organic synthesis on unprotected DNA. Halpin DR, Lee JA, Wrenn SJ, Harbury PB. PLoS Biol. 2004; 2 (7): E175
• In vitro selection and prediction of TIP47 protein-interaction interfaces. Burguete AS, Harbury PB, Pfeffer SR. Nat Methods. 2004; 1 (1): 55-60
• Structural test of the parameterized-backbone method for protein design. Plecs JJ, Harbury PB, Kim PS, Alber T. J Mol Biol. 2004; 342 (1): 289-97
• Automated design of specificity in molecular recognition. Havranek JJ, Harbury PB. Nat Struct Biol. 2003; 10 (1): 45-52
• Rapid mapping of protein structure, interactions, and ligand binding by misincorporation proton-alkyl exchange. Silverman JA, Harbury PB. J Biol Chem. 2002; 277 (34): 30968-75
• The equilibrium unfolding pathway of a (beta/alpha)8 barrel. Silverman JA, Harbury PB. J Mol Biol. 2002; 324 (5): 1031-40
• Modular enzymes. Khosla C, Harbury PB. Nature. 2001; 409 (6817): 247-52
• Reverse engineering the (beta/alpha )8 barrel fold. Silverman JA, Balakrishnan R, Harbury PB. Proc Natl Acad Sci U S A. 2001; 98 (6): 3092-7
• Tanford-Kirkwood electrostatics for protein modeling. Havranek JJ, Harbury PB. Proc Natl Acad Sci U S A. 1999; 96 (20): 11145-50
• High-resolution protein design with backbone freedom. Harbury PB, Plecs JJ, Tidor B, Alber T, Kim PS. Science. 1998; 282 (5393): 1462-7
• Springs and zippers: coiled coils in SNARE-mediated membrane fusion. Harbury PA, Structure. 1998; 6 (12): 1487-91
• Repacking protein cores with backbone freedom: structure prediction for coiled coils. Harbury PB, Tidor B, Kim PS. Proc Natl Acad Sci U S A. 1995; 92 (18): 8408-12
• Crystal structure of an isoleucine-zipper trimer. Harbury PB, Kim PS, Alber T. Nature. 1994; 371 (6492): 80-3
• A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants. Harbury PB, Zhang T, Kim PS, Alber T. Science. 1993; 262 (5138): 1401-7
• Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II. Nitiss JL, Liu YX, Harbury P, Jannatipour M, Wasserman R, Wang JC. Cancer Res. 1992; 52 (16): 4467-72
• Extraction of protein-bound ATP and ADP from human platelets in plasma. Beurling-Harbury C, Harbury PB. Thromb Haemost. 1990; 63 (2): 286-90
• Functional distinctions between yeast TATA elements. Harbury PA, Struhl K. Mol Cell Biol. 1989; 9 (12): 5298-304
• DNA twisting and the affinity of bacteriophage 434 operator for bacteriophage 434 repressor. Koudelka GB, Harbury P, Harrison SC, Ptashne M. Proc Natl Acad Sci U S A. 1988; 85 (13): 4633-7
• Transcriptional activation by yeast GCN4, a functional homolog to the jun oncoprotein. Struhl K, Brandl CJ, Chen W, Harbury PA, Hope IA, Mahadevan S. Cold Spring Harb Symp Quant Biol. 1988: 53 Pt 2 701-9