Publications
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A nexus for receptor recycling.
Pfeffer SR,
Nat Cell Biol.
2013;
15
(5):
446-8
-
Rab GTPase regulation of membrane identity.
Pfeffer SR,
Curr Opin Cell Biol.
2013
-
Cargo carriers from the Golgi to the cell surface.
Pfeffer SR,
EMBO J.
2012;
31
(20):
3954-5
-
RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36.
Nottingham RM,
Pusapati GV, Ganley IG, Barr FA, Lambright DG, Pfeffer SR.
J Biol Chem.
2012;
287
(27):
22740-8
-
Rab GTPase localization and Rab cascades in Golgi transport.
Pfeffer SR,
Biochem Soc Trans.
2012;
40
(6):
1373-7
-
Ric1-Rgp1 complex is a guanine nucleotide exchange factor for the late Golgi Rab6A GTPase and an effector of the medial Golgi Rab33B GTPase.
Pusapati GV,
Luchetti G, Pfeffer SR.
J Biol Chem.
2012;
287
(50):
42129-37
-
TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling.
Goueli BS,
Powell MB, Finger EC, Pfeffer SR.
Proc Natl Acad Sci U S A.
2012;
109
(39):
15787-92
-
The 5-phosphatase OCRL mediates retrograde transport of the mannose 6-phosphate receptor by regulating a Rac1-cofilin signalling module.
van Rahden VA,
Brand K, Najm J, Heeren J, Pfeffer SR, Braulke T, Kutsche K.
Hum Mol Genet.
2012;
21
(23):
5019-38
-
Entry at the trans-face of the Golgi.
Pfeffer SR,
Cold Spring Harb Perspect Biol.
2011;
3
(3)
-
GCC185 plays independent roles in Golgi structure maintenance and AP-1-mediated vesicle tethering.
Brown FC,
Schindelhaim CH, Pfeffer SR.
J Cell Biol.
2011;
194
(5):
779-87
-
Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding.
Deffieu MS,
Pfeffer SR.
Proc Natl Acad Sci U S A.
2011;
108
(47):
18932-6
-
RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
Nottingham RM,
Ganley IG, Barr FA, Lambright DG, Pfeffer SR.
J Biol Chem.
2011;
286
(38):
33213-22
-
An update on transport vesicle tethering.
Brown FC,
Pfeffer SR.
Mol Membr Biol.
2010;
27
(8):
457-61
-
How the Golgi works: a cisternal progenitor model.
Pfeffer SR,
Proc Natl Acad Sci U S A.
2010;
107
(46):
19614-8
-
Membrane traffic.
Pfeffer SR,
Novick PJ.
Curr Opin Cell Biol.
2010;
22
(4):
419-21
-
Recent advances in understanding Golgi biogenesis.
Pfeffer SR,
F1000 Biol Rep.
2010:
2
32
-
Two Rabs for exosome release.
Pfeffer SR,
Nat Cell Biol.
2010;
12
(1):
3-4
-
Unconventional secretion by autophagosome exocytosis.
Pfeffer SR,
J Cell Biol.
2010;
188
(4):
451-2
-
Defining the boundaries: Rab GEFs and GAPs.
Nottingham RM,
Pfeffer SR.
Proc Natl Acad Sci U S A.
2009;
106
(34):
14185-6
-
Multiple Rab GTPase binding sites in GCC185 suggest a model for vesicle tethering at the trans-Golgi.
Hayes GL,
Brown FC, Haas AK, Nottingham RM, Barr FA, Pfeffer SR.
Mol Biol Cell.
2009;
20
(1):
209-17
-
Multiple routes of protein transport from endosomes to the trans Golgi network.
Pfeffer SR,
FEBS Lett.
2009;
583
(23):
3811-6
-
RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport.
Espinosa EJ,
Calero M, Sridevi K, Pfeffer SR.
Cell.
2009;
137
(5):
938-48
-
A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells.
Ganley IG,
Espinosa E, Pfeffer SR.
J Cell Biol.
2008;
180
(1):
159-72
-
Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.
Burguete AS,
Fenn TD, Brunger AT, Pfeffer SR.
Cell.
2008;
132
(2):
286-98
-
Team effort by TRAPP forces a nucleotide fumble.
Nottingham RM,
Pfeffer SR.
Cell.
2008;
133
(7):
1141-3
-
WHAMMing into the Golgi.
Hayes GL,
Pfeffer SR.
Dev Cell.
2008;
15
(2):
171-2
-
TBC1D20 is a Rab1 GTPase-activating protein that mediates hepatitis C virus replication.
Sklan EH,
Serrano RL, Einav S, Pfeffer SR, Lambright DG, Glenn JS.
J Biol Chem.
2007;
282
(50):
36354-61
-
Unsolved mysteries in membrane traffic.
Pfeffer SR,
Annu Rev Biochem.
2007:
76
629-45
-
A functional role for the GCC185 golgin in mannose 6-phosphate receptor recycling.
Reddy JV,
Burguete AS, Sridevi K, Ganley IG, Nottingham RM, Pfeffer SR.
Mol Biol Cell.
2006;
17
(10):
4353-63
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Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells.
Ganley IG,
Pfeffer SR.
J Biol Chem.
2006;
281
(26):
17890-9
-
Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling.
Reddy JV,
Ganley IG, Pfeffer SR.
PLoS One.
2006:
1
e19
-
TIP47 is a key effector for Rab9 localization.
Aivazian D,
Serrano RL, Pfeffer S.
J Cell Biol.
2006;
173
(6):
917-26
-
A model for Rab GTPase localization.
Pfeffer S,
Biochem Soc Trans.
2005;
33
(Pt 4):
627-30
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Misincorporation proton-alkyl exchange (MPAX): engineering cysteine probes into proteins.
Burguete AS,
Harbury PB, Pfeffer SR.
Curr Protoc Protein Sci.
2005:
Chapter 26
Unit26.1
-
Structural clues to Rab GTPase functional diversity.
Pfeffer SR,
J Biol Chem.
2005;
280
(16):
15485-8
-
In vitro selection and prediction of TIP47 protein-interaction interfaces.
Burguete AS,
Harbury PB, Pfeffer SR.
Nat Methods.
2004;
1
(1):
55-60
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Rab9 GTPase regulates late endosome size and requires effector interaction for its stability.
Ganley IG,
Carroll K, Bittova L, Pfeffer S.
Mol Biol Cell.
2004;
15
(12):
5420-30
-
Targeting Rab GTPases to distinct membrane compartments.
Pfeffer S,
Aivazian D.
Nat Rev Mol Cell Biol.
2004;
5
(11):
886-96
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Membrane domains in the secretory and endocytic pathways.
Pfeffer S,
Cell.
2003;
112
(4):
507-17
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Self-assembly is important for TIP47 function in mannose 6-phosphate receptor transport.
Sincock PM,
Ganley IG, Krise JP, Diederichs S, Sivars U, O'Connor B, Ding L, Pfeffer SR.
Traffic.
2003;
4
(1):
18-25
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Yip3 catalyses the dissociation of endosomal Rab-GDI complexes.
Sivars U,
Aivazian D, Pfeffer SR.
Nature.
2003;
425
(6960):
856-9
-
Identification of residues in TIP47 essential for Rab9 binding.
Hanna J,
Carroll K, Pfeffer SR.
Proc Natl Acad Sci U S A.
2002;
99
(11):
7450-4
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Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cells.
Barbero P,
Bittova L, Pfeffer SR.
J Cell Biol.
2002;
156
(3):
511-8
-
Constructing a Golgi complex.
Pfeffer SR,
J Cell Biol.
2001;
155
(6):
873-5
-
Membrane transport: retromer to the rescue.
Pfeffer SR,
Curr Biol.
2001;
11
(3):
R109-11
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Rab GTPases: specifying and deciphering organelle identity and function.
Pfeffer SR,
Trends Cell Biol.
2001;
11
(12):
487-91
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Role of Rab9 GTPase in facilitating receptor recruitment by TIP47.
Carroll KS,
Hanna J, Simon I, Krise J, Barbero P, Pfeffer SR.
Science.
2001;
292
(5520):
1373-6
-
TIP47 is not a component of lipid droplets.
Barbero P,
Buell E, Zulley S, Pfeffer SR.
J Biol Chem.
2001;
276
(26):
24348-51
-
Vesicle tethering factors united.
Pfeffer S,
Mol Cell.
2001;
8
(4):
729-30
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Quantitative analysis of TIP47-receptor cytoplasmic domain interactions: implications for endosome-to-trans Golgi network trafficking.
Krise JP,
Sincock PM, Orsel JG, Pfeffer SR.
J Biol Chem.
2000;
275
(33):
25188-93
-
Recognition of the 300-kDa mannose 6-phosphate receptor cytoplasmic domain by 47-kDa tail-interacting protein.
Orsel JG,
Sincock PM, Krise JP, Pfeffer SR.
Proc Natl Acad Sci U S A.
2000;
97
(16):
9047-51
-
Mapmodulin, cytoplasmic dynein, and microtubules enhance the transport of mannose 6-phosphate receptors from endosomes to the trans-golgi network.
Itin C,
Ulitzur N, Mühlbauer B, Pfeffer SR.
Mol Biol Cell.
1999;
10
(7):
2191-7
-
Transport-vesicle targeting: tethers before SNAREs.
Pfeffer SR,
Nat Cell Biol.
1999;
1
(1):
E17-22
-
Characterization of a 76 kDa endosomal, multispanning membrane protein that is highly conserved throughout evolution.
Schimmöller F,
Díaz E, Mühlbauer B, Pfeffer SR.
Gene.
1998;
216
(2):
311-8
-
Rab GTPases, directors of vesicle docking.
Schimmöller F,
Simon I, Pfeffer SR.
J Biol Chem.
1998;
273
(35):
22161-4
-
TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking.
Díaz E,
Pfeffer SR.
Cell.
1998;
93
(3):
433-43
-
A novel Rab9 effector required for endosome-to-TGN transport.
Díaz E,
Schimmöller F, Pfeffer SR.
J Cell Biol.
1997;
138
(2):
283-90
-
A novel assay reveals a role for soluble N-ethylmaleimide-sensitive fusion attachment protein in mannose 6-phosphate receptor transport from endosomes to the trans Golgi network.
Itin C,
Rancaño C, Nakajima Y, Pfeffer SR.
J Biol Chem.
1997;
272
(44):
27737-44
-
Biochemical characterization of mapmodulin, a protein that binds microtubule-associated proteins.
Ulitzur N,
Rancaño C, Pfeffer SR.
J Biol Chem.
1997;
272
(48):
30577-82
-
Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI.
Dirac-Svejstrup AB,
Sumizawa T, Pfeffer SR.
EMBO J.
1997;
16
(3):
465-72
-
Mapmodulin: a possible modulator of the interaction of microtubule-associated proteins with microtubules.
Ulitzur N,
Humbert M, Pfeffer SR.
Proc Natl Acad Sci U S A.
1997;
94
(10):
5084-9
-
Phosphatidylinositol 3-kinase is not required for recycling of mannose 6-phosphate receptors from late endosomes to the trans-Golgi network.
Nakajima Y,
Pfeffer SR.
Mol Biol Cell.
1997;
8
(4):
577-82
-
Vesicle traffic: get your coat!
Schimmöller F,
Itin C, Pfeffer S.
Curr Biol.
1997;
7
(4):
R235-7
-
Transport vesicle docking: SNAREs and associates.
Pfeffer SR,
Annu Rev Cell Dev Biol.
1996:
12
441-61
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Expression of Rab9 protein in Escherichia coli: purification and isoprenylation in vitro.
Riederer MA,
Soldati T, Dirac-Svejstrup AB, Pfeffer SR.
Methods Enzymol.
1995:
257
15-21
-
Quantitative analysis of the interactions between prenyl Rab9, GDP dissociation inhibitor-alpha, and guanine nucleotides.
Shapiro AD,
Pfeffer SR.
J Biol Chem.
1995;
270
(19):
11085-90
-
Rab GDP dissociation inhibitor: putting rab GTPases in the right place.
Pfeffer SR,
Dirac-Svejstrup AB, Soldati T.
J Biol Chem.
1995;
270
(29):
17057-9
-
Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes.
Soldati T,
Rancaño C, Geissler H, Pfeffer SR.
J Biol Chem.
1995;
270
(43):
25541-8
-
Reconstitution of Rab9 endosomal targeting and nucleotide exchange using purified Rab9-GDP dissociation inhibitor complexes and endosome-enriched membranes.
Soldati T,
Shapiro AD, Pfeffer SR.
Methods Enzymol.
1995:
257
253-9
-
Selective membrane recruitment of Rab GTPases.
Pfeffer SR,
Soldati T, Geissler H, Rancaño C, Dirac-Svejstrup B.
Cold Spring Harb Symp Quant Biol.
1995:
60
221-7
-
Clues to brain function from bakers' yeast.
Pfeffer SR,
Proc Natl Acad Sci U S A.
1994;
91
(6):
1987-8
-
Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network.
Riederer MA,
Soldati T, Shapiro AD, Lin J, Pfeffer SR.
J Cell Biol.
1994;
125
(3):
573-82
-
Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange.
Soldati T,
Shapiro AD, Svejstrup AB, Pfeffer SR.
Nature.
1994;
369
(6475):
76-8
-
Rab GTPases: master regulators of membrane trafficking.
Pfeffer SR,
Curr Opin Cell Biol.
1994;
6
(4):
522-6
-
Rab-GDI presents functional Rab9 to the intracellular transport machinery and contributes selectivity to Rab9 membrane recruitment.
Dirac-Svejstrup AB,
Soldati T, Shapiro AD, Pfeffer SR.
J Biol Chem.
1994;
269
(22):
15427-30
-
Receptor extracellular domains may contain trafficking information. Studies of the 300-kDa mannose 6-phosphate receptor.
Dintzis SM,
Velculescu VE, Pfeffer SR.
J Biol Chem.
1994;
269
(16):
12159-66
-
Biochemical analysis of rab9, a ras-like GTPase involved in protein transport from late endosomes to the trans Golgi network.
Shapiro AD,
Riederer MA, Pfeffer SR.
J Biol Chem.
1993;
268
(10):
6925-31
-
Rab GDI: a solubilizing and recycling factor for rab9 protein.
Soldati T,
Riederer MA, Pfeffer SR.
Mol Biol Cell.
1993;
4
(4):
425-34
-
Cytoplasmic dynein participates in the centrosomal localization of the Golgi complex.
Corthésy-Theulaz I,
Pauloin A, Pfeffer SR.
J Cell Biol.
1992;
118
(6):
1333-45
-
GTP-binding proteins in intracellular transport.
Pfeffer SR,
Trends Cell Biol.
1992;
2
(2):
41-6
-
Microtubule-mediated Golgi capture by semiintact Chinese hamster ovary cells.
Corthésy-Theulaz I,
Pfeffer SR.
Methods Enzymol.
1992:
219
159-65
-
Mannose-6-phosphate receptors and their role in protein sorting along the pathway to lysosomes.
Pfeffer SR,
Cell Biophys.
1991 Oct-Dec;
19
(1-3):
131-40
-
Identification of a novel, N-ethylmaleimide-sensitive cytosolic factor required for vesicular transport from endosomes to the trans-Golgi network in vitro.
Goda Y,
Pfeffer SR.
J Cell Biol.
1991;
112
(5):
823-31
-
Targeting of proteins to the lysosome.
Pfeffer SR,
Curr Top Microbiol Immunol.
1991:
170
43-65
-
A budding and fusing journey through the secretory pathway. Genetic and In Vitro Analysis of Cell Compartmentalization: A UCLA symposium, Taos, NM, USA, February 3-9, 1990.
Pfeffer SR,
New Biol.
1990;
2
(5):
430-4
-
Antibodies to clathrin inhibit endocytosis but not recycling to the trans Golgi network in vitro.
Draper RK,
Goda Y, Brodsky FM, Pfeffer SR.
Science.
1990;
248
(4962):
1539-41
-
Compartmentation of the Golgi complex: brefeldin-A distinguishes trans-Golgi cisternae from the trans-Golgi network.
Chege NW,
Pfeffer SR.
J Cell Biol.
1990;
111
(3):
893-9
-
The mannose 6-phosphate receptor cytoplasmic domain is not sufficient to alter the cellular distribution of a chimeric EGF receptor.
Dintzis SM,
Pfeffer SR.
EMBO J.
1990;
9
(1):
77-84
-
Cell-free systems to study vesicular transport along the secretory and endocytic pathways.
Goda Y,
Pfeffer SR.
FASEB J.
1989;
3
(13):
2488-95
-
Intracellular transport of the mannose-6-phosphate receptor.
Pfeffer SR,
Goda Y, Chege NW.
Prog Clin Biol Res.
1988:
270
365-75
-
Mannose 6-phosphate receptors and their role in targeting proteins to lysosomes.
Pfeffer SR,
J Membr Biol.
1988;
103
(1):
7-16
-
Selective recycling of the mannose 6-phosphate/IGF-II receptor to the trans Golgi network in vitro.
Goda Y,
Pfeffer SR.
Cell.
1988;
55
(2):
309-20
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