Publications
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BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration.
Brack AS,
Murphy-Seiler F, Hanifi J, Deka J, Eyckerman S, Keller C, Aguet M, Rando TA.
Dev Biol.
2009;
335
(1):
93-105
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Preventing oxidative stress: a new role for XBP1.
Liu Y,
Adachi M, Zhao S, Hareyama M, Koong AC, Luo D, Rando TA, Imai K, Shinomura Y.
Cell Death Differ.
2009;
16
(6):
847-57
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Biomarker system for studying muscle, stem cells, and cancer in vivo.
Nishijo K,
Hosoyama T, Bjornson CR, Schaffer BS, Prajapati SI, Bahadur AN, Hansen MS, Blandford MC, McCleish AT, Rubin BP, Epstein JA, Rando TA, Capecchi MR, Keller C.
FASEB J.
2009;
23
(8):
2681-90
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Focal adhesion kinase signaling regulates the expression of caveolin 3 and beta1 integrin, genes essential for normal myoblast fusion.
Quach NL,
Biressi S, Reichardt LF, Keller C, Rando TA.
Mol Biol Cell.
2009;
20
(14):
3422-35
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Get personal with gene therapy for muscular dystrophy.
Rando TA,
Lancet Neurol.
2008;
7
(3):
196-8
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Technology insight: therapy for Duchenne muscular dystrophy-an opportunity for personalized medicine?
Lim LE,
Rando TA.
Nat Clin Pract Neurol.
2008;
4
(3):
149-58
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A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis.
Brack AS,
Conboy IM, Conboy MJ, Shen J, Rando TA.
Cell Stem Cell.
2008;
2
(1):
50-9
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[Proteasomal degradation of Pax3 in skeletal muscle progenitors: one ubiquitin does the trick!]
Boutet SC,
Rando TA.
Med Sci (Paris).
2008;
24
(1):
31-3
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Tissue ageing: do insights into molecular mechanisms of ageing lead to new therapeutic strategies?
Simm A,
Rando TA.
Exp Gerontol.
2008;
43
(7):
603-4
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Turning back time: reversing tissue pathology to enhance stem cell engraftment.
Rando TA,
Cell Stem Cell.
2008;
3
(3):
232-4
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Stem cell review series: aging of the skeletal muscle stem cell niche.
Gopinath SD,
Rando TA.
Aging Cell.
2008;
7
(4):
590-8
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High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny.
Conboy MJ,
Karasov AO, Rando TA.
PLoS Biol.
2007;
5
(5):
e102
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Ageing: from stem to stern.
Brunet A,
Rando TA.
Nature.
2007;
449
(7160):
288-91
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Intrinsic changes and extrinsic influences of myogenic stem cell function during aging.
Brack AS,
Rando TA.
Stem Cell Rev.
2007;
3
(3):
226-37
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Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis.
Brack AS,
Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C, Rando TA.
Science.
2007;
317
(5839):
807-10
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Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors.
Boutet SC,
Disatnik MH, Chan LS, Iori K, Rando TA.
Cell.
2007;
130
(2):
349-62
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The immortal strand hypothesis: segregation and reconstruction.
Rando TA,
Cell.
2007;
129
(7):
1239-43
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Non-viral gene therapy for Duchenne muscular dystrophy: progress and challenges.
Rando TA,
Biochim Biophys Acta.
2007;
1772
(2):
263-71
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Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integration.
Bertoni C,
Jarrahian S, Wheeler TM, Li Y, Olivares EC, Calos MP, Rando TA.
Proc Natl Acad Sci U S A.
2006;
103
(2):
419-24
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Stem cells, ageing and the quest for immortality.
Rando TA,
Nature.
2006;
441
(7097):
1080-6
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Prognostic value of telomere length: the long and short of it.
Rando TA,
Ann Neurol.
2006;
60
(2):
155-7
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Long-term increase in mVEGF164 in mouse hindlimb muscle mediated by phage phiC31 integrase after nonviral DNA delivery.
Portlock JL,
Keravala A, Bertoni C, Lee S, Rando TA, Calos MP.
Hum Gene Ther.
2006;
17
(8):
871-6
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The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis.
Luo D,
Renault VM, Rando TA.
Semin Cell Dev Biol.
2005 Aug-Oct;
16
(4-5):
612-22
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The adult muscle stem cell comes of age.
Rando TA,
Nat Med.
2005;
11
(8):
829-31
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NF90 regulates cell cycle exit and terminal myogenic differentiation by direct binding to the 3'-untranslated region of MyoD and p21WAF1/CIP1 mRNAs.
Shi L,
Zhao G, Qiu D, Godfrey WR, Vogel H, Rando TA, Hu H, Kao PN.
J Biol Chem.
2005;
280
(19):
18981-9
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Aging, stem cells and tissue regeneration: lessons from muscle.
Conboy IM,
Rando TA.
Cell Cycle.
2005;
4
(3):
407-10
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Rejuvenation of aged progenitor cells by exposure to a young systemic environment.
Conboy IM,
Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA.
Nature.
2005;
433
(7027):
760-4
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Strand bias in oligonucleotide-mediated dystrophin gene editing.
Bertoni C,
Morris GE, Rando TA.
Hum Mol Genet.
2005;
14
(2):
221-33
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Stem cells in postnatal myogenesis: molecular mechanisms of satellite cell quiescence, activation and replenishment.
Dhawan J,
Rando TA.
Trends Cell Biol.
2005;
15
(12):
666-73
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Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle.
Sherwood RI,
Christensen JL, Conboy IM, Conboy MJ, Rando TA, Weissman IL, Wagers AJ.
Cell.
2004;
119
(4):
543-54
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The bi-directional translocation of MARCKS between membrane and cytosol regulates integrin-mediated muscle cell spreading.
Disatnik MH,
Boutet SC, Pacio W, Chan AY, Ross LB, Lee CH, Rando TA.
J Cell Sci.
2004;
117
(Pt 19):
4469-79
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Artificial sweeteners--enhancing glycosylation to treat muscular dystrophies.
Rando TA,
N Engl J Med.
2004;
351
(12):
1254-6
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Restoration of dystrophin expression in mdx muscle cells by chimeraplast-mediated exon skipping.
Bertoni C,
Lau C, Rando TA.
Hum Mol Genet.
2003;
12
(10):
1087-99
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The regulation of catalase gene expression in mouse muscle cells is dependent on the CCAAT-binding factor NF-Y.
Luo D,
Rando TA.
Biochem Biophys Res Commun.
2003;
303
(2):
609-18
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Remarkable preservation of undigested muscle tissue within a Late Cretaceous tyrannosaurid coprolite from Alberta, Canada.
Chin K,
Eberth DA, Schweitzer MH, Rando TA, Sloboda WJ, Horner JR.
Palaios.
2003;
18
(3):
286-94
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A caveolin-3 mutant that causes limb girdle muscular dystrophy type 1C disrupts Src localization and activity and induces apoptosis in skeletal myotubes.
Smythe GM,
Eby JC, Disatnik MH, Rando TA.
J Cell Sci.
2003;
116
(Pt 23):
4739-49
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Notch-mediated restoration of regenerative potential to aged muscle.
Conboy IM,
Conboy MJ, Smythe GM, Rando TA.
Science.
2003;
302
(5650):
1575-7
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The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis.
Conboy IM,
Rando TA.
Dev Cell.
2002;
3
(3):
397-409
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Activation of an adipogenic program in adult myoblasts with age.
Taylor-Jones JM,
McGehee RE, Rando TA, Lecka-Czernik B, Lipschitz DA, Peterson CA.
Mech Ageing Dev.
2002;
123
(6):
649-61
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Oxidative stress and the pathogenesis of muscular dystrophies.
Rando TA,
Am J Phys Med Rehabil.
2002;
81
(11 Suppl):
S175-86
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Copper/zinc superoxide dismutase: more is not necessarily better!
Rando TA,
Epstein CJ.
Ann Neurol.
1999;
46
(1):
135-6
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Muscle cells from mdx mice have an increased susceptibility to oxidative stress.
Rando TA,
Disatnik MH, Yu Y, Franco A.
Neuromuscul Disord.
1998;
8
(1):
14-21
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Two regions of the ryanodine receptor involved in coupling with L-type Ca2+ channels.
Nakai J,
Sekiguchi N, Rando TA, Allen PD, Beam KG.
J Biol Chem.
1998;
273
(22):
13403-6
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Heterogeneity among muscle precursor cells in adult skeletal muscles with differing regenerative capacities.
Pavlath GK,
Thaloor D, Rando TA, Cheong M, English AW, Zheng B.
Dev Dyn.
1998;
212
(4):
495-508
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Dystrophic muscle in mice chimeric for expression of alpha5 integrin.
Taverna D,
Disatnik MH, Rayburn H, Bronson RT, Yang J, Rando TA, Hynes RO.
J Cell Biol.
1998;
143
(3):
849-59
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Evidence of oxidative stress in mdx mouse muscle: studies of the pre-necrotic state.
Disatnik MH,
Dhawan J, Yu Y, Beal MF, Whirl MM, Franco AA, Rando TA.
J Neurol Sci.
1998;
161
(1):
77-84
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Overexpression of copper/zinc superoxide dismutase: a novel cause of murine muscular dystrophy.
Rando TA,
Crowley RS, Carlson EJ, Epstein CJ, Mohapatra PK.
Ann Neurol.
1998;
44
(3):
381-6
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Myoblast-mediated expression of colony stimulating factor-1 (CSF-1) in the cytokine-deficient op/op mouse.
Dhawan J,
Rando TA, Elson SE, Lee F, Stanley ER, Blau HM.
Somat Cell Mol Genet.
1996;
22
(5):
363-81
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Genetic analysis of alpha 4 integrin functions in the development of mouse skeletal muscle.
Yang JT,
Rando TA, Mohler WA, Rayburn H, Blau HM, Hynes RO.
J Cell Biol.
1996;
135
(3):
829-35
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Tetracycline-regulated gene expression following direct gene transfer into mouse skeletal muscle.
Dhawan J,
Rando TA, Elson SL, Bujard H, Blau HM.
Somat Cell Mol Genet.
1995;
21
(4):
233-40
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The fate of myoblasts following transplantation into mature muscle.
Rando TA,
Pavlath GK, Blau HM.
Exp Cell Res.
1995;
220
(2):
383-9
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Pseudochoreoathetosis. Movements associated with loss of proprioception.
Sharp FR,
Rando TA, Greenberg SA, Brown L, Sagar SM.
Arch Neurol.
1994;
51
(11):
1103-9
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Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy.
Rando TA,
Blau HM.
J Cell Biol.
1994;
125
(6):
1275-87
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Transient immunosuppressive treatment leads to long-term retention of allogeneic myoblasts in hybrid myofibers.
Pavlath GK,
Rando TA, Blau HM.
J Cell Biol.
1994;
127
(6 Pt 2):
1923-32
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Tumor suppression by RNA from the 3' untranslated region of alpha-tropomyosin.
Rastinejad F,
Conboy MJ, Rando TA, Blau HM.
Cell.
1993;
75
(6):
1107-17
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Spontaneous intracranial hypotension: report of two cases and review of the literature.
Rando TA,
Fishman RA.
Neurology.
1992;
42
(3 Pt 1):
481-7
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Wolfram syndrome: evidence of a diffuse neurodegenerative disease by magnetic resonance imaging.
Rando TA,
Horton JC, Layzer RB.
Neurology.
1992;
42
(6):
1220-4
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Rapid and slow gating of veratridine-modified sodium channels in frog myelinated nerve.
Rando TA,
J Gen Physiol.
1989;
93
(1):
43-65
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Saxitoxin blocks batrachotoxin-modified sodium channels in the node of Ranvier in a voltage-dependent manner.
Rando TA,
Strichartz GR.
Biophys J.
1986;
49
(3):
785-94
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The interaction between the activator agents batrachotoxin and veratridine and the gating processes of neuronal sodium channels.
Rando TA,
Wang GK, Strichartz GR.
Mol Pharmacol.
1986;
29
(5):
467-77
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Localization of neurons in the rat spinal cord which project to the superior cervical ganglion.
Rando TA,
Bowers CW, Zigmond RE.
J Comp Neurol.
1981;
196
(1):
73-83