Publications
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Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon.
Wang H,
Ouyang Y, Somers WG, Chia W, Lu B.
Nature.
2007;
449
(7158):
96-100
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PAR-1 kinase phosphorylates Dlg and regulates its postsynaptic targeting at the Drosophila neuromuscular junction.
Zhang Y,
Guo H, Kwan H, Wang JW, Kosek J, Lu B.
Neuron.
2007;
53
(2):
201-15
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Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin.
Yang Y,
Gehrke S, Imai Y, Huang Z, Ouyang Y, Wang JW, Yang L, Beal MF, Vogel H, Lu B.
Proc Natl Acad Sci U S A.
2006;
103
(28):
10793-8
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PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila.
Nishimura I,
Yang Y, Lu B.
Cell.
2004;
116
(5):
671-82
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Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila.
Yang Y,
Nishimura I, Imai Y, Takahashi R, Lu B.
Neuron.
2003;
37
(6):
911-24
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Drosophila models of neurodegenerative diseases.
Lu B,
Vogel H.
Annu Rev Pathol.
2009:
4
315-42
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Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery.
Yang Y,
Ouyang Y, Yang L, Beal MF, McQuibban A, Vogel H, Lu B.
Proc Natl Acad Sci U S A.
2008;
105
(19):
7070-5
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Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila.
Imai Y,
Gehrke S, Wang HQ, Takahashi R, Hasegawa K, Oota E, Lu B.
EMBO J.
2008;
27
(18):
2432-43
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Activation of PAR-1 Kinase and Stimulation of Tau Phosphorylation by Diverse Signals Require the Tumor Suppressor Protein LKB1
Wang, J-W.,
Imai Y., Lu, B..
The Journal of Neuroscience.
2007;
27
(3):
574-581
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Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling.
Yang Y,
Gehrke S, Haque ME, Imai Y, Kosek J, Yang L, Beal MF, Nishimura I, Wakamatsu K, Ito S, Takahashi R, Lu B.
Proc Natl Acad Sci U S A.
2005;
102
(38):
13670-5
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RNA interference technologies for understanding and treating neurodegenerative diseases.
Lu B,
Neuromolecular Med.
2004;
6
(1):
1-12
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Putting a PARKINg brake on neurodegeneration.
Lu B,
Mol Psychiatry.
2004;
9
(1):
6-7
-
Adherens junctions inhibit asymmetric division in the Drosophila epithelium.
Lu B,
Roegiers F, Jan LY, Jan YN.
Nature.
2001;
409
(6819):
522-5
-
PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling.
Sun TQ,
Lu B, Feng JJ, Reinhard C, Jan YN, Fantl WJ, Williams LT.
Nat Cell Biol.
2001;
3
(7):
628-36
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Drosophila par-1 is required for oocyte differentiation and microtubule organization.
Cox DN,
Lu B, Sun TQ, Williams LT, Jan YN.
Curr Biol.
2001;
11
(2):
75-87
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Control of cell divisions in the nervous system: symmetry and asymmetry.
Lu B,
Jan L, Jan YN.
Annu Rev Neurosci.
2000:
23
531-56
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Flamingo controls the planar polarity of sensory bristles and asymmetric division of sensory organ precursors in Drosophila.
Lu B,
Usui T, Uemura T, Jan L, Jan YN.
Curr Biol.
1999;
9
(21):
1247-50
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Modes of protein movement that lead to the asymmetric localization of partner of Numb during Drosophila neuroblast division.
Lu B,
Ackerman L, Jan LY, Jan YN.
Mol Cell.
1999;
4
(6):
883-91
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Asymmetric cell division: lessons from flies and worms.
Lu B,
Jan LY, Jan YN.
Curr Opin Genet Dev.
1998;
8
(4):
392-9
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Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors.
Lu B,
Rothenberg M, Jan LY, Jan YN.
Cell.
1998;
95
(2):
225-35
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