Publications
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PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance.
Mukundan L,
Odegaard JI, Morel CR, Heredia JE, Mwangi JW, Ricardo-Gonzalez RR, Goh YP, Eagle AR, Dunn SE, Awakuni JU, Nguyen KD, Steinman L, Michie SA, Chawla A.
Nat Med.
2009;
15
(11):
1266-72
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Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.
Odegaard JI,
Ricardo-Gonzalez RR, Red Eagle A, Vats D, Morel CR, Goforth MH, Subramanian V, Mukundan L, Ferrante AW, Chawla A.
Cell Metab.
2008;
7
(6):
496-507
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Mechanisms of macrophage activation in obesity-induced insulin resistance.
Odegaard JI,
Chawla A.
Nat Clin Pract Endocrinol Metab.
2008;
4
(11):
619-26
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Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance.
Odegaard JI,
Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Red Eagle A, Vats D, Brombacher F, Ferrante AW, Chawla A.
Nature.
2007;
447
(7148):
1116-20
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Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation.
Vats D,
Mukundan L, Odegaard JI, Zhang L, Smith KL, Morel CR, Wagner RA, Greaves DR, Murray PJ, Chawla A.
Cell Metab.
2006;
4
(1):
13-24
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Control of macrophage activation and function by PPARs.
Chawla A,
Circ Res.
2010;
106
(10):
1559-69
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A role for GPRx, a novel GPR3/6/12-related G-protein coupled receptor, in the maintenance of meiotic arrest in Xenopus laevis oocytes.
Ríos-Cardona D,
Ricardo-González RR, Chawla A, Ferrell JE.
Dev Biol.
2008;
317
(1):
380-8
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Quantitative expansion of ES cell-derived myeloid progenitors capable of differentiating into macrophages.
Odegaard JI,
Vats D, Zhang L, Ricardo-Gonzalez R, Smith KL, Sykes DB, Kamps MP, Chawla A.
J Leukoc Biol.
2007;
81
(3):
711-9
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Role of PPARgamma in macrophage biology and atherosclerosis.
Zhang L,
Chawla A.
Trends Endocrinol Metab.
2004;
15
(10):
500-5
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PPARdelta is a very low-density lipoprotein sensor in macrophages.
Chawla A,
Lee CH, Barak Y, He W, Rosenfeld J, Liao D, Han J, Kang H, Evans RM.
Proc Natl Acad Sci U S A.
2003;
100
(3):
1268-73
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Transcriptional repression of atherogenic inflammation: modulation by PPARdelta.
Lee CH,
Chawla A, Urbiztondo N, Liao D, Boisvert WA, Evans RM, Curtiss LK.
Science.
2003;
302
(5644):
453-7
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A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis.
Chawla A,
Boisvert WA, Lee CH, Laffitte BA, Barak Y, Joseph SB, Liao D, Nagy L, Edwards PA, Curtiss LK, Evans RM, Tontonoz P.
Mol Cell.
2001;
7
(1):
161-71
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Nuclear receptors and lipid physiology: opening the X-files.
Chawla A,
Repa JJ, Evans RM, Mangelsdorf DJ.
Science.
2001;
294
(5548):
1866-70
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PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation.
Chawla A,
Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM.
Nat Med.
2001;
7
(1):
48-52
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