Publications
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EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
Ardito CM,
Grüner BM, Takeuchi KK, Lubeseder-Martellato C, Teichmann N, Mazur PK, Delgiorno KE, Carpenter ES, Halbrook CJ, Hall JC, Pal D, Briel T, Herner A, Trajkovic-Arsic M, Sipos B, Liou GY, Storz P, Murray NR, Threadgill DW, Sibilia M, Washington MK, Wilson CL, Schmid RM, Raines EW, Crawford HC, Siveke JT.
Cancer Cell.
2012;
22
(3):
304-17
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Expression and clinicopathological significance of notch signaling and cell-fate genes in biliary tract cancer.
Mazur PK,
Riener MO, Jochum W, Kristiansen G, Weber A, Schmid RM, Siveke JT.
Am J Gastroenterol.
2012;
107
(1):
126-35
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Genetically engineered mouse models of pancreatic cancer: unravelling tumour biology and progressing translational oncology.
Mazur PK,
Siveke JT.
Gut.
2012;
61
(10):
1488-500
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MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.
Grüner BM,
Hahne H, Mazur PK, Trajkovic-Arsic M, Maier S, Esposito I, Kalideris E, Michalski CW, Kleeff J, Rauser S, Schmid RM, Küster B, Walch A, Siveke JT.
PLoS One.
2012;
7
(6):
e39424
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Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.
Aichler M,
Seiler C, Tost M, Siveke J, Mazur PK, Da Silva-Buttkus P, Bartsch DK, Langer P, Chiblak S, Dürr A, Höfler H, Klöppel G, Müller-Decker K, Brielmeier M, Esposito I.
J Pathol.
2012;
226
(5):
723-34
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Early requirement of Rac1 in a mouse model of pancreatic cancer.
Heid I,
Lubeseder-Martellato C, Sipos B, Mazur PK, Lesina M, Schmid RM, Siveke JT.
Gastroenterology.
2011;
141
(2):
719-30, 730.e1-7
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Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.
Viatour P,
Ehmer U, Saddic LA, Dorrell C, Andersen JB, Lin C, Zmoos AF, Mazur PK, Schaffer BE, Ostermeier A, Vogel H, Sylvester KG, Thorgeirsson SS, Grompe M, Sage J.
J Exp Med.
2011;
208
(10):
1963-76
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Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo.
Mazur PK,
Grüner BM, Nakhai H, Sipos B, Zimber-Strobl U, Strobl LJ, Radtke F, Schmid RM, Siveke JT.
PLoS One.
2010;
5
(10):
e13578
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Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma.
Mazur PK,
Einwächter H, Lee M, Sipos B, Nakhai H, Rad R, Zimber-Strobl U, Strobl LJ, Radtke F, Klöppel G, Schmid RM, Siveke JT.
Proc Natl Acad Sci U S A.
2010;
107
(30):
13438-43
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Conditional ablation of Notch signaling in pancreatic development.
Nakhai H,
Siveke JT, Klein B, Mendoza-Torres L, Mazur PK, Algül H, Radtke F, Strobl L, Zimber-Strobl U, Schmid RM.
Development.
2008;
135
(16):
2757-65
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Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice.
Geisler F,
Nagl F, Mazur PK, Lee M, Zimber-Strobl U, Strobl LJ, Radtke F, Schmid RM, Siveke JT.
Hepatology.
2008;
48
(2):
607-16
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Notch signaling is required for exocrine regeneration after acute pancreatitis.
Siveke JT,
Lubeseder-Martellato C, Lee M, Mazur PK, Nakhai H, Radtke F, Schmid RM.
Gastroenterology.
2008;
134
(2):
544-55