Publications
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Alternative activation in systemic juvenile idiopathic arthritis monocytes.
Macaubas C,
Nguyen KD, Peck A, Buckingham J, Deshpande C, Wong E, Alexander HC, Chang SY, Begovich A, Sun Y, Park JL, Pan KH, Lin R, Lih CJ, Augustine EM, Phillips C, Hadjinicolaou AV, Lee T, Mellins ED.
Clin Immunol.
2012;
142
(3):
362-72
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Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis.
Nguyen KD,
Qiu Y, Cui X, Goh YP, Mwangi J, David T, Mukundan L, Brombacher F, Locksley RM, Chawla A.
Nature.
2011;
480
(7375):
104-8
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Macrophage-mediated inflammation in metabolic disease.
Chawla A,
Nguyen KD, Goh YP.
Nat Rev Immunol.
2011;
11
(11):
738-49
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Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways.
Nguyen KD,
Macaubas C, Nadeau KC, Truong P, Yoon T, Lee T, Park JL, Mellins ED.
Blood.
2011;
117
(14):
3793-8
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Distribution of circulating cells in systemic juvenile idiopathic arthritis across disease activity states.
Macaubas C,
Nguyen K, Deshpande C, Phillips C, Peck A, Lee T, Park JL, Sandborg C, Mellins ED.
Clin Immunol.
2010;
134
(2):
206-16
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Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements.
Boyd SD,
Gaƫta BA, Jackson KJ, Fire AZ, Marshall EL, Merker JD, Maniar JM, Zhang LN, Sahaf B, Jones CD, Simen BB, Hanczaruk B, Nguyen KD, Nadeau KC, Egholm M, Miklos DB, Zehnder JL, Collins AM.
J Immunol.
2010;
184
(12):
6986-92
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Plasma profiles in active systemic juvenile idiopathic arthritis: Biomarkers and biological implications.
Ling XB,
Park JL, Carroll T, Nguyen KD, Lau K, Macaubas C, Chen E, Lee T, Sandborg C, Milojevic D, Kanegaye JT, Gao S, Burns J, Schilling J, Mellins ED.
Proteomics.
2010;
10
(24):
4415-30
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TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway.
Nguyen KD,
Vanichsarn C, Nadeau KC.
Allergy Asthma Clin Immunol.
2010;
6
(1):
4
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Impaired IL-10-dependent induction of tolerogenic dendritic cells by CD4+CD25hiCD127lo/- natural regulatory T cells in human allergic asthma.
Nguyen KD,
Vanichsarn C, Nadeau KC.
Am J Respir Crit Care Med.
2009;
180
(9):
823-33
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Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing.
Boyd SD,
Marshall EL, Merker JD, Maniar JM, Zhang LN, Sahaf B, Jones CD, Simen BB, Hanczaruk B, Nguyen KD, Nadeau KC, Egholm M, Miklos DB, Zehnder JL, Fire AZ.
Sci Transl Med.
2009;
1
(12):
12ra23
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Oligoarticular and polyarticular JIA: epidemiology and pathogenesis.
Macaubas C,
Nguyen K, Milojevic D, Park JL, Mellins ED.
Nat Rev Rheumatol.
2009;
5
(11):
616-26
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PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance.
Mukundan L,
Odegaard JI, Morel CR, Heredia JE, Mwangi JW, Ricardo-Gonzalez RR, Goh YP, Eagle AR, Dunn SE, Awakuni JU, Nguyen KD, Steinman L, Michie SA, Chawla A.
Nat Med.
2009;
15
(11):
1266-72
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Selective deregulation in chemokine signaling pathways of CD4+CD25(hi)CD127(lo)/(-) regulatory T cells in human allergic asthma.
Nguyen KD,
Vanichsarn C, Fohner A, Nadeau KC.
J Allergy Clin Immunol.
2009;
123
(4):
933-9.e10
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Increased cytotoxicity of CD4+ invariant NKT cells against CD4+CD25hiCD127lo/- regulatory T cells in allergic asthma.
Nguyen KD,
Vanichsarn C, Nadeau KC.
Eur J Immunol.
2008;
38
(7):
2034-45
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Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development.
Milojevic D,
Nguyen KD, Wara D, Mellins ED.
Pediatr Rheumatol Online J.
2008:
6
20
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XCL1 enhances regulatory activities of CD4+ CD25(high) CD127(low/-) T cells in human allergic asthma.
Nguyen KD,
Fohner A, Booker JD, Dong C, Krensky AM, Nadeau KC.
J Immunol.
2008;
181
(8):
5386-95
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Altered phosphorylated signal transducer and activator of transcription profile of CD4+CD161+ T cells in asthma: modulation by allergic status and oral corticosteroids.
Gernez Y,
Tirouvanziam R, Nguyen KD, Herzenberg LA, Krensky AM, Nadeau KC.
J Allergy Clin Immunol.
2007;
120
(6):
1441-8