Publications
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Anhedonia requires MC4R-mediated synaptic adaptations in nucleus accumbens.
Lim BK,
Huang KW, Grueter BA, Rothwell PE, Malenka RC.
Nature.
2012;
487
(7406):
183-9
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Integrating synaptic plasticity and striatal circuit function in addiction.
Grueter BA,
Rothwell PE, Malenka RC.
Curr Opin Neurobiol.
2012;
22
(3):
545-51
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Protracted manifestations of acute dependence after a single morphine exposure.
Rothwell PE,
Thomas MJ, Gewirtz JC.
Psychopharmacology (Berl).
2012;
219
(4):
991-8
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An anatomical basis for opponent process mechanisms of opiate withdrawal.
Radke AK,
Rothwell PE, Gewirtz JC.
J Neurosci.
2011;
31
(20):
7533-9
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Environmental novelty causes stress-like adaptations at nucleus accumbens synapses: implications for studying addiction-related plasticity.
Rothwell PE,
Kourrich S, Thomas MJ.
Neuropharmacology.
2011;
61
(7):
1152-9
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Synaptic adaptations in the nucleus accumbens caused by experiences linked to relapse.
Rothwell PE,
Kourrich S, Thomas MJ.
Biol Psychiatry.
2011;
69
(11):
1124-6
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Episodic withdrawal promotes psychomotor sensitization to morphine.
Rothwell PE,
Gewirtz JC, Thomas MJ.
Neuropsychopharmacology.
2010;
35
(13):
2579-89
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Parsing spontaneous and evoked neurotransmission on both sides of the synapse.
Rothwell PE,
J Neurosci.
2010;
30
(19):
6480-1
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Distinct profiles of anxiety and dysphoria during spontaneous withdrawal from acute morphine exposure.
Rothwell PE,
Thomas MJ, Gewirtz JC.
Neuropsychopharmacology.
2009;
34
(10):
2285-95
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Protein kinase C mediates the synergistic interaction between agonists acting at alpha2-adrenergic and delta-opioid receptors in spinal cord.
Overland AC,
Kitto KF, Chabot-Doré AJ, Rothwell PE, Fairbanks CA, Stone LS, Wilcox GL.
J Neurosci.
2009;
29
(42):
13264-73
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Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia.
Harris AC,
Rothwell PE, Gewirtz JC.
Psychopharmacology (Berl).
2008;
196
(4):
649-60
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Cocaine experience controls bidirectional synaptic plasticity in the nucleus accumbens.
Kourrich S,
Rothwell PE, Klug JR, Thomas MJ.
J Neurosci.
2007;
27
(30):
7921-8
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