Publications
-
Encyclopedia of Signaling Molecules - contribution: Mps1
Chu ML,
Eyers PA.
Encyclopedia of Signaling Molecules, Choi, S. (Ed.), Springer-Verlag New York, Inc. ISBN 978-1-4419-0461-4.
2012:
1103-1114
-
Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6.
Ahn VE,
Chu ML, Choi HJ, Tran D, Abo A, Weis WI.
Dev Cell.
2011;
21
(5):
862-73
-
Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes.
Chu ML,
Lang Z, Chavas LM, Neres J, Fedorova OS, Tabernero L, Cherry M, Williams DH, Douglas KT, Eyers PA.
Biochemistry.
2010;
49
(8):
1689-701
-
Drug-resistant aurora A mutants for cellular target validation of the small molecule kinase inhibitors MLN8054 and MLN8237.
Sloane DA,
Trikic MZ, Chu ML, Lamers MB, Mason CS, Mueller I, Savory WJ, Williams DH, Eyers PA.
ACS Chem Biol.
2010;
5
(6):
563-76
-
Discovery and exploitation of inhibitor-resistant aurora and polo kinase mutants for the analysis of mitotic networks.
Scutt PJ,
Chu ML, Sloane DA, Cherry M, Bignell CR, Williams DH, Eyers PA.
J Biol Chem.
2009;
284
(23):
15880-93
-
Phosphoregulation of human Mps1 kinase.
Tyler RK,
Chu ML, Johnson H, McKenzie EA, Gaskell SJ, Eyers PA.
Biochem J.
2009;
417
(1):
173-81
-
Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125.
Chu ML,
Chavas LM, Douglas KT, Eyers PA, Tabernero L.
J Biol Chem.
2008;
283
(31):
21495-500
-
Fusion core structure of the severe acute respiratory syndrome coronavirus (SARS-CoV): in search of potent SARS-CoV entry inhibitors.
Chu LH,
Chan SH, Tsai SN, Wang Y, Cheng CH, Wong KB, Waye MM, Ngai SM.
J Cell Biochem.
2008;
104
(6):
2335-47
-
Rapid peptide-based screening on the substrate specificity of severe acute respiratory syndrome (SARS) coronavirus 3C-like protease by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Chu LH,
Choy WY, Tsai SN, Rao Z, Ngai SM.
Protein Sci.
2006;
15
(4):
699-709