Publications
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A strategy to enhance the binding affinity of fluorophore-aptamer pairs for RNA tagging with neomycin conjugation.
Jeon J,
Lee KH, Rao J.
Chem Commun (Camb).
2012;
48
(80):
10034-6
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Efficient method for site-specific 18F-labeling of biomolecules using the rapid condensation reaction between 2-cyanobenzothiazole and cysteine.
Jeon J,
Shen B, Xiong L, Miao Z, Lee KH, Rao J, Chin FT.
Bioconjug Chem.
2012;
23
(9):
1902-8
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An RNA aptamer that selectively recognizes symmetric dimethylation of arginine 8 in the histone H3 N-terminal peptide.
Hyun S,
Lee KH, Han A, Yu J.
Nucleic Acid Ther.
2011;
21
(3):
157-63
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Methylation-mediated control of aurora kinase B and Haspin with epigenetically modified histone H3 N-terminal peptides.
Han A,
Lee KH, Hyun S, Lee NJ, Lee SJ, Hwang H, Yu J.
Bioorg Med Chem.
2011;
19
(7):
2373-7
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Combining SELEX screening and rational design to develop light-up fluorophore-RNA aptamer pairs for RNA tagging.
Lee J,
Lee KH, Jeon J, Dragulescu-Andrasi A, Xiao F, Rao J.
ACS Chem Biol.
2010;
5
(11):
1065-74
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Histone H3 N-terminal peptide binds directly to its own mRNA: a possible mode of feedback inhibition to control translation.
Lee KH,
Lee NJ, Hyun S, Park YK, Yang EG, Lee JK, Jeong S, Yu J.
Chembiochem.
2009;
10
(8):
1313-6
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Alpha-helical peptide containing N,N-dimethyl lysine residues displays low-nanomolar and highly specific binding to RRE RNA.
Hyun S,
Kim HJ, Lee NJ, Lee KH, Lee Y, Ahn DR, Kim K, Jeong S, Yu J.
J Am Chem Soc.
2007;
129
(15):
4514-5
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An RNA aptamer that recognizes a specific conformation of the protein calsenilin.
Lee KH,
Jeong S, Yang EG, Park YK, Yu J.
Bioorg Med Chem.
2007;
15
(24):
7545-52
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A strategy for the design of selective RNA binding agents. Preparation and RRE RNA binding affinities of a neomycin-peptide nucleic acid heteroconjugate library.
Hyun S,
Lee KH, Yu J.
Bioorg Med Chem Lett.
2006;
16
(18):
4757-9
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A hybrid molecule that prohibits amyloid fibrils and alleviates neuronal toxicity induced by beta-amyloid (1-42).
Lee KH,
Shin BH, Shin KJ, Kim DJ, Yu J.
Biochem Biophys Res Commun.
2005;
328
(4):
816-23
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An approach to enhance specificity against RNA targets using heteroconjugates of aminoglycosides and chloramphenicol (or linezolid).
Lee J,
Kwon M, Lee KH, Jeong S, Hyun S, Shin KJ, Yu J.
J Am Chem Soc.
2004;
126
(7):
1956-7
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Mimicry of tandem repeat peptides against cell surface carbohydrates.
Kwon M,
Jeong S, Lee KH, Park YK, Yu J.
J Am Chem Soc.
2002;
124
(47):
13996-7
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