Publications
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New insights into the therapeutic inhibition of voltage-gated sodium channels.
Ahern CA,
Eastwood AL, Dougherty DA, Horn R.
Channels (Austin).
2008 Jan-Feb;
2
(1):
1-3
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Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels.
Ahern CA,
Eastwood AL, Dougherty DA, Horn R.
Circ Res.
2008;
102
(1):
86-94
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Calcium block of single sodium channels: role of a pore-lining aromatic residue.
Santarelli VP,
Eastwood AL, Dougherty DA, Ahern CA, Horn R.
Biophys J.
2007;
93
(7):
2341-9
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A cation-pi interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block.
Santarelli VP,
Eastwood AL, Dougherty DA, Horn R, Ahern CA.
J Biol Chem.
2007;
282
(11):
8044-51
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A cation-pi interaction between extracellular TEA and an aromatic residue in potassium channels.
Ahern CA,
Eastwood AL, Lester HA, Dougherty DA, Horn R.
J Gen Physiol.
2006;
128
(6):
649-57
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Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation.
Kumar R,
Eastwood AL, Brown ML, Laurie GW.
J Mol Biol.
2002;
319
(3):
593-602