Department: Stanford Cancer Institute
Division: Hematopoietic Cell Transplant
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Academic Appointments Assistant Professor - Med Center Line, Medicine - Blood & Marrow Transplantation
Member, Stanford Cancer Institute
Clinical Focus- Cancer > Blood and Marrow Transplant
- Cancer > Hematology
- Blood and Marrow Transplantation
Research InterestResearch interest in utilizing post-transplant adoptive cellular immunotherapy to reduce GVHD and relapse in patients with high risk hematologic malignancies.
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Academic Appointments Professor, Pediatrics - Infectious Diseases
Member, Child Health Research Institute
Member, Stanford Cancer Institute
Professor, Microbiology & Immunology
Clinical Focus- Infectious Diseases, Pediatric
- Pediatric Infectious Disease
Research InterestOur laboratory investigates the pathogenesis of varicella zoster virus (VZV) infection, focusing on the functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections.
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Professor - Med Center Line, Medicine - Blood & Marrow Transplantation
Member, Stanford Cancer Institute
Clinical Focus- Cancer > Blood and Marrow Transplant
- Blood and Marrow Transplantation
- Blood and Marrow Transplantation / Infectious Diseases
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Academic Appointments Member, Stanford Cancer Institute
Member, Bio-X
Clinical Focus- Intensive Care, Pediatric
- Pediatric Critical Care Medicine
Research InterestHemofiltration and survival in respiratory failure after bone marrow transplantation. A randomized, controlled multi center trial. J. DiCarlo, principal investigator. Stanford University IRB #3, Protocol #78861. Pediatric Health Research Grant, Department of Pediatrics, Stanford University (03/2003 09/2004), and Leukemia & Lymphoma Society Translational Research Grant #6090-05 [J. DiCarlo (PI), 10/2004 09/2007]. Proteomic analysis of ultrafiltrate and serum in ARDS after transplantati..
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Academic Appointments Professor Emeritus, Medicine - Hematology
Emeritus Faculty, Acad Council, Medicine - Hematology
Member, Stanford Cancer Institute
Member, Bio-X
Clinical Focus- Cancer > Hematology
- Hematology
- Myelodysplastic Syndromes
Research InterestRegulation of hematopoiesis in myeloid malignancies with special emphasis on myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Laboratory studies utilize DNA microarrays to determine differential gene expression in MDS and AML. Transcriptomic abnormalities are also being evaluated using RNA-Seq and proteomic technologies. Translational clinical studies focus on using specific biologic targeting agents to treat these disorders.
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Academic Appointments Associate Professor - Med Center Line, Medicine - Blood & Marrow Transplantation
Member, Stanford Cancer Institute
Clinical Focus- Cancer > Blood and Marrow Transplant
- Cancer > Hematology
- Blood and Marrow Transplantation
Research InterestClinical research in allogeneic and autologous hematopoietic cell transplantation (HCT), more specifically, allogeneic transplantation and graft versus host disease. Exploring methods of improving prevention and treatment of GVHD as well as the long term follow-up and/or quality of life of affected patients.
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Academic Appointments Associate Professor - Med Center Line, Medicine - Blood & Marrow Transplantation
Member, Stanford Cancer Institute
Clinical Focus- Cancer > Blood and Marrow Transplant
- Cancer > Hematology
- Blood and Marrow Transplantation
Research Interesthaploidentical transplantation, follicular lymphoma, adoptive immunotherapy,supportive care
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Academic Appointments Professor, Health Research & Policy - Biostatistics
Member, Stanford Cancer Institute
Professor (By courtesy), Natural Sciences Cluster - Statistics
Research InterestBiostatistics, clinical trials, longitudinal studies, casual inference from observational studies, genetic tissue banking, informed consent. Trial designs for dynamic (adaptive) treatment regimes, psychiatric research, cancer.
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Academic Appointments Associate Professor - Med Center Line, Medicine - Blood & Marrow Transplantation
Member, Stanford Cancer Institute
Clinical Focus- Cancer > Blood and Marrow Transplant
- Cancer > Hematology
- Blood and Marrow Transplantation
Research InterestDr. Lowsky's research is focused on understanding the role of regulatory T cells in the prevention of GVHD and in promoting immune tolerance following organ transplantation.
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Academic Appointments Assistant Professor - Med Center Line, Medicine - Blood & Marrow Transplantation
Member, Stanford Cancer Institute
Clinical Focus- Cancer > Blood and Marrow Transplant
- Cancer > Hematology
- Aplastic Anemia
Research InterestInvestigates the targets of immune responses after human allogeneic stem cell transplantation. BMT patients develop antibodies against minor histocompatibility antigens (mHA) that are associated with chronic graft-v-host disease (cGVHD) and disease remission. Current projects: investigate Ab anti-tumor mechanism, high-throughput serologic identification of novel mHA in the development of GVHD and prevention of disease relapse, and clinical trials of B cell therapeutics for cGVHD.
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Academic Appointments Professor, Medicine - Blood & Marrow Transplantation
Member, Stanford Cancer Institute
Clinical Focus- Cancer > Blood and Marrow Transplant
- Cancer > Hematology
- Blood and Marrow Transplantation
Research InterestOur labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells.
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Academic Appointments Member, Stanford Cancer Institute
Clinical Focus- Oncology
- Oncology (Cancer)
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Academic Appointments Professor, Structural Biology
Member, Stanford Cancer Institute
Professor, Microbiology & Immunology
Research InterestThe Parham laboratory investigates the biology, genetics, and evolution of MHC class I molecules and NK cell receptors.
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Academic Appointments Associate Professor, Medicine - Blood & Marrow Transplantation
Member, Stanford Cancer Institute
Clinical Focus- Cancer > Blood and Marrow Transplant
- Blood and Marrow Transplantation
- Hematology
Research InterestTransplantation of defined populations of allogeneic hematopoietic cells. Specifically, the way in which hematopoietic cell grafts alter antigen specific immune responses to allo-, auto- and viral antigens. The cellular and molecular basis of resistance to engraftment of allogeneic hematopoietic stem cells.
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Academic Appointments Professor, Medicine - Immunology & Rheumatology
Member, Stanford Cancer Institute
Clinical Focus- Immunology and Rheumatology
- Rheumatology
Research InterestMechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation.
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Academic Appointments Professor, Pediatrics - Stem Cell Transplantation
Member, Stanford Cancer Institute
Clinical Focus- Hematology, Pediatric
- Oncology (Cancer), Pediatric
- Pediatric Hematology-Oncology
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
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