Community Academic Profiles

Department: Pathology

F

  • Academic Appointments Clinical Professor,  Pathology
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Clinical Chemistry & Immunology
  • Academic Appointments Emeritus Faculty, Acad Council,  Pathology
    Clinical Focus
    • Pathology
    Research Interest

    Radiation injury in mammalian tissues. Mechanisms of cerebral malaria. Effects of cytokines on angiogenesis.

  • Academic Appointments Professor,  Medicine - Oncology
    Member,  Stanford Cancer Institute
    Member,  Bio-X
    Professor,  Pathology
    Clinical Focus
    • Cancer  >  Lymphoma
    • Hodgkin's Disease
    • Hodgkin's Disease - Hematology
    Research Interest

    My laboratory investigates how oncogenes initiate and sustain tumorigenesis. I have developed model systems whereby I can conditionally activate oncogenes in normal human and mouse cells in tissue culture or in specific tissues of transgenic mice. In particular using the tetracycline regulatory system, I have generated a conditional model system for MYC-induced tumors. I have shown that cancers caused by the conditional over-expression of the MYC proto-oncogene regress with its inactivation.

  • Academic Appointments Professor - Med Center Line,  Pathology
  • Academic Appointments Professor,  Pathology
    Member,  Bio-X
    Member,  Child Health Research Institute
    Professor,  Genetics
    Research Interest

    We study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as "self" versus "nonself" or "wanted" versus "unwanted".

  • Academic Appointments Acting Assistant Professor,  Pathology
    Clinical Focus
    • Anatomic/Clinical Pathology
    Research Interest

    My research interest is in gynecologic and obstetric pathology, specifically in the origin and pathogenesis of serous ovarian carcinoma and the diagnostic difficulties surrounding trophoblastic disorders and neoplasia in the placenta.

  • Academic Appointments Assistant Professor - Med Center Line,  Pathology
    Clinical Focus
    • Clinical Pathology
    • Pathology
    Research Interest

    Our interest lies at the frontier of Transfusion Medicine by developing and optimizing new cellular therapies such as islet transplantation for patients with Type 1 Diabetes.

  • Academic Appointments Professor,  Pathology
    Clinical Focus
    • Pathology
    • Transfusion Medicine
    Research Interest

    Our research focus is on the early events of hepatitis C virus infection- virus attachment and entry into susceptible cells. The approach is through the generation and functional studies of human monoclonal antibodies (HMAbs) to the virus envelope proteins with an emphasis on antibodies to conformational epitopes.

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