Community Academic Profiles

Department: Genetics

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  • Academic Appointments Associate Professor,  Pediatrics - Cancer Biology
    Member,  Bio-X
    Member,  Stanford Cancer Institute
    Member,  Child Health Research Institute
    Associate Professor,  Genetics
    Research Interest

    We are interested in the links between the basic cell cycle machinery and the factors controlling self-renewal, differentiation, and regeneration. In particular, we are intrigued by the differences and the similarities between "normal" cells, cancer cells, and stem cells. We investigate the mechanisms by which normal cells become tumor cells, and we aim to understand the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells.

  • Academic Appointments Postdoctoral Research fellowGenetics
    Research Interest

    Population Genetics of Native Americans, Anthropology, Human Migrations Process, Ancient Populations.

  • Academic Appointments Ph.D. Student in Genetics, admitted Autumn 2012
  • Academic Appointments Professor,  Developmental Biology
    Member,  Bio-X
    Member,  Stanford Cancer Institute
    Professor,  Bioengineering
    Professor,  Genetics
    Professor (By courtesy),  Biology (School of Humanities and Sciences)
    Research Interest

    Our research is focused on the genetic regulation of animal development and its relation to birth defects, cancer, and neurodegeneration. We study mechanisms and functions of Hedgehog (Hh) signaling, which controls cell fates and growth, in the context of normal development and brain cancer. We study a neurodegenerative disease, Niemann-Pick C syndrome, that affects intracellular organelle movements and sterol homeostasis.

  • Academic Appointments Ph.D. Student in Genetics, admitted Autumn 2010
  • Academic Appointments Associate Professor,  Genetics
    Member,  Stanford Cancer Institute
    Research Interest

    Evolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species

  • Academic Appointments Postdoctoral Research fellowGenetics
  • Academic Appointments Associate Professor,  Pathology
    Member,  Bio-X
    Associate Professor,  Genetics
    Research Interest

    We are interested in the systems biology of molecular phenotypes, and how genetic variation affects them. The lab combines experimental approaches in developing mouse embryos as well as human cancers with computational analyses. Our main data engine is high-throughput sequencing. Please refer to our web site for more information: http://mendel.stanford.edu/SidowLab/index.html

  • Academic Appointments Postdoctoral Research fellowGenetics
  • Academic Appointments Other Research Assistant,  Genetics
  • Academic Appointments Professor,  Genetics
    Member,  Stanford Cancer Institute
    Member,  Child Health Research Institute
    Member,  Bio-X
    Research Interest

    We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans. 1) Transcriptomes To annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously..

  • Academic Appointments Postdoctoral Research fellowGenetics
  • Academic Appointments Postdoctoral Research fellowGenetics
  • Academic Appointments Professor,  Biology (School of Humanities and Sciences)
    Member,  Bio-X
    Professor,  Genetics
    Research Interest

    We use the tools of genetics, microscopy, and biochemistry to understand fundamental questions of cell biology: How are cells organized by the cytoskeleton? How do the centrosome and cilium control cell control cell signaling? How is cell division coordinated with duplication of the centrosome, and what goes wrong in cancer cells defective in this coordination?

  • Academic Appointments Postdoctoral Research fellowGenetics
  • Academic Appointments Associate Professor,  Urology
    Member,  Stanford Cancer Institute
    Member,  Bio-X
    Associate Professor,  Genetics
    Research Interest

    My lab focuses on understanding the molecular mechanism of transcription factors that govern the transformation of normal mammalian cells to a neoplastic state. We are especially interested in the action of the nuclear hormone receptors and the interactions between the receptors and other signaling pathways in related human disorders.

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