Community Academic Profiles

Department: Genetics

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  • Academic Appointments Professor,  Pathology
    Member,  Child Health Research Institute
    Member,  Bio-X
    Professor,  Genetics
    Research Interest

    We study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as "self" versus "nonself" or "wanted" versus "unwanted".

  • Academic Appointments Associate Professor,  Medicine - Oncology
    Member,  Bio-X
    Member,  Stanford Cancer Institute
    Associate Professor,  Genetics
    Associate Professor (By courtesy),  Pediatrics
    Clinical Focus
    • Cancer  >  GI Oncology
    • Cancer Genetics
    • Gastrointestinal Cancers - Genetics
    Research Interest

    Mammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNA damage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.

  • Academic Appointments Professor Emeritus,  Genetics
    Emeritus Faculty, Acad Council,  Genetics
    Professor,  Pediatrics - Medical Genetics
    Clinical Focus
    • Neurogenetics
    • Clinical Genetics
    Research Interest

    Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models. Integration of genomic information into medical care.

  • Academic Appointments Ph.D. Student in Genetics, admitted Autumn 2012
  • Academic Appointments Professor,  Developmental Biology
    Member,  Stanford Cancer Institute
    Member,  Bio-X
    Professor,  Genetics
    Research Interest

    Regulation of stem cell division and self-renewal Cell type specific transcription machinery and regulation of cell differentiation Developmental regulation of cell cycle progression during male meiosis Molecular dissection of the mechanism of cytokinesis.

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