Department: Structural Biology

P

• 
  Pande, Vijay Satyanand
  Academic Appointments Professor,  Natural Sciences Cluster - Chemistry
  Member,  Bio-X
  Professor (By courtesy),  Structural Biology
  Professor (By courtesy),  Computer Science
  
  Research Interest

  The central theme of our research is to develop and apply novel theoretical methods to understand the physical properties of biological molecules, such as proteins, nucleic acids, lipid membranes, and small molecule therapeutics (eg protein folding or lipid vesicle fusion). As these phenomena are complex, my research employs novel theoretical and computational techniques. We apply these methods to develop novel therapeutics for protein misfolding diseases, such as Alzheimer's Disease.
• 
  Parham, Peter 
  Academic Appointments Professor,  Structural Biology
  Member,  Stanford Cancer Institute
  Professor,  Microbiology & Immunology
  
  Research Interest

  The Parham laboratory investigates the biology, genetics, and evolution of MHC class I molecules and NK cell receptors.
• 
  Pereyaslavets, Leonid 
  Academic Appointments Postdoctoral Research fellow, Structural Biology
  
• 
  Podoly, Erez 
  Academic Appointments Postdoctoral Research fellow, Structural Biology
  
• 
  Puglisi, Joseph 
  Academic Appointments Professor,  Structural Biology
  Member,  Bio-X
  
  Research Interest

  The Puglisi group investigates the role of RNA in cellular processes and disease. We investigate dynamics using single-molecule approaches. Our goal is a unified picture of structure, dynamics and function. We are currently focused on the mechanism and regulation of translation, and the role of RNA in viral infections. A long-term goal is to target processes involving RNA with novel therapeutic strategies.
• 
  Puglisi, Elisabetta 
  Academic Appointments Assistant Professor (Research),  Structural Biology
  
  Research Interest

  Viral infections and subsequent host response depend on multiple RNA-protein interaction. My research focuses on the structural and functional characterization of RNA-protein complexes involved in viral infection. Current research aims to understand how the Human Immunodeficiency Virus (HIV) initiates its replication upon host infection. We use NMR spectroscopy and x-ray crystallography to study the structure of the initiation complex, formed by a host tRNA and HIV genomic RNA, coupled with bio..