Department: Child Health Research Institute

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  Kahana, Madelyn 
  Academic Appointments Member,  Child Health Research Institute
  
  Clinical Focus

  • Critical Care Medicine
  • Pediatric Anesthesiology
  • Pediatric pain management
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  Kay, Mark 
  Academic Appointments Professor,  Pediatrics - Human Gene Therapy
  Member,  Child Health Research Institute
  Member,  Bio-X
  Member,  Stanford Cancer Institute
  Professor,  Genetics
  
  Research Interest

  Mark A. Kay, M.D., Ph.D. Director of the Program in Human Gene Therapy and Professor in the Departments of Pediatrics and Genetics. Respected worldwide for his work in gene therapy for hemophilia, Dr. Kay and his laboratory focus on establishing the scientific principles and developing the technologies needed for achieving persistent and therapeutic levels of gene expression in vivo. The major disease models are hemophilia, hepatitis C, and hepatitis B viral infections.
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  Kennedy, William 
  Academic Appointments Associate Professor - Med Center Line,  Urology
  Member,  Child Health Research Institute
  
  Clinical Focus

  • Urology, Pediatric
  • Pediatric Urology
  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Kerner, John 
  Academic Appointments Professor - Med Center Line,  Pediatrics - Gastroenterology
  Member,  Child Health Research Institute
  
  Clinical Focus

  • Gastroenterology/Nutrition/Hepatology, Pediatric
  • Pediatric Gastroenterology
  Research Interest

  I am interested in pediatric nutritional support and have experience evaluating new enteral and parenteral products especially for the neonate (I studied a "new" I.V. fat product for Abbott; I participated in a multicenter trial of a formula with fish oil in it for neonates with Mead Johnson and a multicenter trial of a new human milk fortifier for Wyeth).

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
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  Khavari, Paul 
  Academic Appointments Professor,  Dermatology
  Member,  Child Health Research Institute
  Member,  Stanford Cancer Institute
  Member,  Bio-X
  
  Clinical Focus

  • Cancer  >  Cutaneous (Dermatologic) Oncology
  • Dermatology
  • General Dermatology
  Research Interest

  We work in epithelial tissue as a model system to study stem cell biology, cancer and new molecular therapeutics. Epithelia cover external and internal body surfaces and undergo constant self-renewal while responding to diverse environmental stimuli. Epithelial homeostasis precisely balances stem cell-sustained proliferation and differentiation-associated cell death, a balance which is lost in many human diseases, including cancer, 90% of which arise in epithelial tissues.
• 
  Khosla, Chaitan 
  Academic Appointments Professor,  Chemical Engineering - Chemical Engineering Operations
  Professor,  Natural Sciences Cluster - Chemistry
  Member,  Bio-X
  Professor (By courtesy),  Biochemistry
  
  Research Interest

  Research interests in this laboratory lie at the interface of chemistry and medicine. For the past several years, we have investigated the catalytic mechanisms of modular megasynthases such as polyketide synthases, with the concomitant goal of harnessing their programmable chemistry for preparing new antibiotics. Recent accomplishments include methods for heterologous production of polyketides; genetically reprogrammed biosynthesis of anthraquinones and polypropionates; and chemo-biosynthesi..
• 
  Kim, Seung 
  Academic Appointments Professor,  Developmental Biology
  Member,  Stanford Cancer Institute
  Member,  Child Health Research Institute
  Member,  Bio-X
  Professor (By courtesy),  Medicine - Oncology
  
  Research Interest

  We study the genetics of pancreatic islet cell differentiation using molecular, embryologic and genetic methods in several model systems, including mice, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. Our knowledge of genetic and cellular pathways governing islet formation has allowed us to use stem cell lines to produce islet replacements in vitro.
• 
  Krams, Sheri 
  Academic Appointments Associate Professor (Research),  Surgery - Multi-Organ Transplantation
  Member,  Bio-X
  Member,  Child Health Research Institute
  
  Research Interest

  Our recent studies have focused on three specific areas: 1) NK cell interactions with dendritic cells and tumors, 2) MicroRNAs as master regulators in transplantation and viral infections and 3) Mechanisms of tolerance induction.
• 
  Kuo, Calvin Jay
  Academic Appointments Professor,  Medicine - Hematology
  Member,  Child Health Research Institute
  Member,  Bio-X
  Member,  Stanford Cancer Institute
  Professor (By courtesy),  Chemical and Systems Biology
  
  Clinical Focus

  • Cancer  >  Hematology
  • Medical Oncology
  Research Interest

  We explore angiogenesis, cancer genomics, intestinal stem cells, and hepatic glucose metabolism. Angiogenesis projects include endothelial miRNA and GPCR ko mice, blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy. Intestinal stem cell projects use primary intestinal culture and mouse genetics to study injury-inducible vs homeostatic stem cells. We use primary organoid cultures of diverse tissues for oncogene functional screening and therapeutics discovery.