Community Academic Profiles

Department: Child Health Research Institute

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  • Academic Appointments Assistant Professor,  Bioengineering
    Member,  Child Health Research Institute
  • Academic Appointments Associate Professor (Research),  Pediatrics - Neonatal and Developmental Medicine
    Member,  Child Health Research Institute
    Research Interest

    Our research focuses on epidemiologic studies related to maternal and child health. Current projects address congenital anomalies of craniofacial, urogenital, musculoskeletal and central nervous system structures and exposures related to nutrition, stress, environmental contaminants, and genes. Physiologic pathways encompassed by these studies include one-carbon metabolism, oxidative stress, HPA axis activation, and sex steroid metabolism. In particular, we are interested in discovering how ..

  • Academic Appointments Associate Professor - Med Center Line,  Anesthesia
    Member,  Child Health Research Institute
    Clinical Focus
    • Anesthesia
    • Anesthesia, Obstetrical
    • Anesthesia, Regional
    Research Interest

    My main research interest is in clinical research related to cesarean delivery anesthesia and labor analgesia.

  • Academic Appointments Assistant Professor - Med Center Line,  Dermatology
    Member,  Child Health Research Institute
    Member,  Stanford Cancer Institute
    Clinical Focus
    • Cancer  >  Cutaneous (Dermatologic) Oncology
    • Dermatology
    • Geriatric dermatology
    Research Interest

    Our current studies focus on aging and skin cancers in human beings and are translational in nature: 1) genetics and epigenetics to promote healthy aging of the skin 2) genetics and epigenetics of skin cancers and drug resistance 3) novel therapies to promote healthy aging of the skin 4) novel therapies for non-melanoma skin cancers 5) induced pluripotent stem cells for regenerative and therapeutic purposes

  • Academic Appointments Associate Professor,  Medicine - Cardiovascular Medicine
    Member,  Child Health Research Institute
    Member,  Bio-X
    Clinical Focus
    • Cardiovascular Disease
    Research Interest

    The ultimate goal of my laboratory is to define the molecular mechanisms underlying cardiovascular development and disease and translate the bench findings to clinical applications. One objective is to understand how the major types of cardiac cells (endocardial, myocardial, epicardial and neural crest cells) interact with each other to generate heart tissues. We are interested in chromatin regulation, transcriptional and signaling events that coordinate their interactions and assembly into hea..

  • Academic Appointments Associate Professor,  Chemical and Systems Biology
    Member,  Bio-X
    Member,  Stanford Cancer Institute
    Member,  Child Health Research Institute
    Associate Professor,  Developmental Biology
    Associate Professor (By courtesy),  Natural Sciences Cluster - Chemistry Department
    Research Interest

    Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis. We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.

  • Academic Appointments Assistant Professor,  Otolaryngology (Head and Neck Surgery)
    Member,  Child Health Research Institute
    Assistant Professor (By courtesy),  Pediatrics
    Clinical Focus
    • Otolaryngology
    • Hearing loss
    • Cholesteotoma
    Research Interest

    Active Wnt signaling maintains somatic stem cells in many organ systems. Using Wnt target genes as markers, we have characterized distinct cell populations with stem cell behavior in the inner ear, an organ thought to be terminally differentiated. Ongoing work focuses on delineating the developing significance of these putative stem/progenitor cells and their behavior after damage.

  • Academic Appointments Assistant Professor - Med Center Line,  Neurology & Neurological Sciences
    Member,  Child Health Research Institute
    Clinical Focus
    • Neurology - Child Neurology
    • Neuro-oncology
    Research Interest

    My laboratory studies childhood brain tumors with a particular focus on medulloblastoma, the most common malignant brain tumor in children. We utilize both top-down and bottom-up strategies to understand the biology of these tumors and identify new therapeutic avenues to more effectively treat these diseases.

  • Academic Appointments Professor,  Pathology
    Member,  Stanford Cancer Institute
    Member,  Child Health Research Institute
    Professor,  Pediatrics
    Clinical Focus
    • Pathology Anatomic
    • Pathology and Laboratory Medicine
    Research Interest

    The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer.

  • Academic Appointments Associate Professor,  Bioengineering
    Member,  Child Health Research Institute
    Member,  Stanford Cancer Institute
    Member,  Bio-X
    Associate Professor (By courtesy),  Chemical Engineering
    Research Interest

    Molecular Bioengineering, Protein Biochemistry and Biotechnology, Cell and Tissue Engineering, Molecular Imaging

  • Academic Appointments Professor - Med Center Line,  Surgery - Multi-Organ Transplantation
    Member,  Child Health Research Institute
    Clinical Focus
    • Pediatric Kidney Transplantation
    • Pediatric Liver Transplantation
    • Adult Liver Transplantation
  • Academic Appointments Associate Professor - Med Center Line,  Pediatrics - Pulmonary Medicine
    Member,  Child Health Research Institute
    Clinical Focus
    • Pediatric Pulmonary
    • Pulmonary Medicine/Cystic Fibrosis, Pediatric
    • Lung Transplantation
    Research Interest

    I am interested in studying the effects of inflammation in the lung, in particular, how N-acetylcysteine may affect and decrease that in CF patients. I am the PI of a multi-center study researching this question. Additionally, in a separate study involving children who have received lung transplants, I am a participating site in an NIH-sponsored observational and mechanistic multi-center study that will examine the role of viral infections in causing chronic graft rejection.

  • Academic Appointments Professor,  Pediatrics - Neonatal and Developmental Medicine
    Member,  Child Health Research Institute
    Member,  Bio-X
    Member,  Stanford Cancer Institute
    Professor,  Microbiology & Immunology
    Professor (By courtesy),  Radiology
    Research Interest

    We develop and use the tools of molecular imaging to understand oncogenesis, reveal patterns of cell migration in immunosurveillance, monitor gene expression, visualize stem cell biology, and assess the distribution of pathogens in living animal models of human biology and disease. Biology doesn't occur in "a vacuum" or on coated plates--it occurs in the living body and that's were we look for biological patterns and responses to insult.

  • Academic Appointments Professor,  Social Sciences Cluster - Sociology
    Member,  Child Health Research Institute
    Member,  Stanford Cancer Institute
    Vice Provost, Academic Council,  Provost's Office Financials
  • Academic Appointments Professor,  Medicine - Cardiovascular Medicine
    Member,  Bio-X
    Member,  Child Health Research Institute
    Clinical Focus
    • Cardiovascular Disease
    • Cardiovascular Medicine
    Research Interest

    Our translational research program in vascular regeneration is focused on generating and characterizing vascular cells from human induced pluripotential stem cells. We are also studying the therapeutic application of these cells in murine models of peripheral arterial disease. In these studies we leverage our longstanding interest in endothelial signaling, eg by nitric oxide synthase (NOS) as well as by nicotinic cholinergic receptors (nAChR).

  • Academic Appointments Professor - Med Center Line,  Pediatrics - Gastroenterology
    Member,  Child Health Research Institute
    Clinical Focus
    • Gastroenterology/Nutrition/Hepatology, Pediatric
    • Pediatric Gastroenterology
    Research Interest

    Gastroenterology, biliary motility, hormonal regulation, embryology, gastrointestinal tract, clinical management of pediatric liver transplant recipients.

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