Department: Chemical and Systems Biology

C

• 
  Chen, James 
  Academic Appointments Associate Professor,  Chemical and Systems Biology
  Member,  Bio-X
  Member,  Child Health Research Institute
  Member,  Stanford Cancer Institute
  Associate Professor,  Developmental Biology
  Associate Professor (By courtesy),  Natural Sciences Cluster - Chemistry Department
  
  Research Interest

  Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis. We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.
• 
  Cimprich, Karlene 
  Academic Appointments Associate Professor,  Chemical and Systems Biology
  Member,  Stanford Cancer Institute
  Member,  Bio-X
  Associate Professor (By courtesy),  Natural Sciences Cluster - Chemistry
  
  Research Interest

  The use of genetic, biochemical and chemical approaches to understand the DNA damage-induced cell cycle checkpoints and the processes that contribute to maintenance of genomic stability.
• 
  Covert, Markus Willard
  Academic Appointments Assistant Professor,  Bioengineering
  Member,  Bio-X
  Assistant Professor (By courtesy),  Chemical and Systems Biology
  
  Research Interest

  Our focus is on building computational models of complex biological processes, and using them to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors.