Department: Biology (School of Humanities and Sciences)
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Academic Appointments Professor, Biology (School of Humanities and Sciences)
Member, Bio-X
Professor, Neurosurgery
Professor, Neurology & Neurological Sciences
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Academic Appointments Professor, Biology (School of Humanities and Sciences)
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Academic Appointments Associate Professor, Biology (School of Humanities and Sciences)
Member, Stanford Cancer Institute
Member, Bio-X
Research InterestMy laboratory has three major research efforts: 1) In vivo fluorescence imaging and behavioral studies of cerebellar-dependent motor control and motor learning. 2) Development and application of fiber-optic fluorescence microendoscopy imaging techniques for studies of learning and memory in behaving mice and for clinical uses in humans. 3) Development of high-throughput, massively parallel imaging techniques for studying brain function in large numbers of Drosophila concurrently.
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Academic Appointments Professor, Developmental Biology
Member, Stanford Cancer Institute
Member, Bio-X
Professor, Bioengineering
Professor, Genetics
Professor (By courtesy), Biology (School of Humanities and Sciences)
Research InterestOur research is focused on the genetic regulation of animal development and its relation to birth defects, cancer, and neurodegeneration. We study mechanisms and functions of Hedgehog (Hh) signaling, which controls cell fates and growth, in the context of normal development and brain cancer. We study a neurodegenerative disease, Niemann-Pick C syndrome, that affects intracellular organelle movements and sterol homeostasis.
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Academic Appointments Professor, Biology (School of Humanities and Sciences)
Professor, Neurobiology
Member, Bio-X
Research InterestThe goal of research in the Shatz Laboratory is to discover how brain circuits are tuned up by experience during critical periods of development both before and after birth by elucidating cellular and molecular mechanisms that transform early fetal and neonatal brain circuits into mature connections. To discover mechanistic underpinnings of circuit tuning, the lab has conducted functional screens for genes regulated by neural activity and studied their function for vision, learning and memory.
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Academic Appointments Associate Professor, Biology (School of Humanities and Sciences)
Member, Bio-X
Associate Professor, Pathology
Research InterestThe connectivity of a neuron (its unique constellation of synaptic inputs and outputs) is essential for its function. Neuronal connections are made with exquisite accuracy between specific types of neurons. How each neuron finds its synaptic partners has been a central question in developmental neurobiology. We utilize the relatively simple nervous system of nematode C. elegans, to search for molecules that can specify synaptic connections and understand the molecular mechanisms of synaptic as
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Academic Appointments Professor, Biology (School of Humanities and Sciences)
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Academic Appointments Professor, Biology (School of Humanities and Sciences)
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Academic Appointments Assistant Professor, Biology (School of Humanities and Sciences)
Member, Bio-X
Assistant Professor (By courtesy), Chemical and Systems Biology
(By courtesy), Chemical and Systems Biology
Research InterestA central aim of the burgeoning field of systems biology is to understand the principles governing genetic control networks. I believe finding the principles underlying genetic circuits will occur through detailed studies and then comparisons of several natural systems. Due to its extensive development as an experimental system, our favorite model, the budding yeast cell cycle, is poised to become central to this enterprise.
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Academic Appointments Professor, Biology (School of Humanities and Sciences)
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Academic Appointments Professor, Biology (School of Humanities and Sciences)
Member, Bio-X
Professor, Genetics
Research InterestWe use the tools of genetics, microscopy, and biochemistry to understand fundamental questions of cell biology: How are cells organized by the cytoskeleton? How do the centrosome and cilium control cell control cell signaling? How is cell division coordinated with duplication of the centrosome, and what goes wrong in cancer cells defective in this coordination?
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