Community Academic Profiles

Department: Biochemistry

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  • Academic Appointments Emeritus Faculty, Acad Council,  Biochemistry
    Member,  Bio-X
    Research Interest

    How are genes regulated to construct a developmental program? How do signals received from other cells change the program and coordinate it for multicellular development? The approach taken by our laboratory group to answer these questions utilizes biochemistry and genetics; genetics to isolate mutants that have particular defects in development and biochemistry to determine the molecular basis of the defects. We study swarming in Myxococcus xanthus that builds fruiting bodies.

  • Academic Appointments Professor,  Chemical Engineering - Chemical Engineering Operations
    Professor,  Natural Sciences Cluster - Chemistry
    Member,  Bio-X
    Professor (By courtesy),  Biochemistry
    Research Interest

    Research interests in this laboratory lie at the interface of chemistry and medicine. For the past several years, we have investigated the catalytic mechanisms of modular megasynthases such as polyketide synthases, with the concomitant goal of harnessing their programmable chemistry for preparing new antibiotics. Recent accomplishments include methods for heterologous production of polyketides; genetically reprogrammed biosynthesis of anthraquinones and polypropionates; and chemo-biosynthesi..

  • Academic Appointments Professor,  Biochemistry
    Member,  Stanford Cancer Institute
    Member,  Bio-X
    Research Interest

    - Lung development and stem cells - Neural control of breathing - Lung diseases including lung cancer - New genetic model organisms for medicine

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