Department: Bio-X

K

• 
  Kaiser, A 
  Academic Appointments Emeritus Faculty, Acad Council,  Biochemistry
  Member,  Bio-X
  
  Research Interest

  How are genes regulated to construct a developmental program? How do signals received from other cells change the program and coordinate it for multicellular development? The approach taken by our laboratory group to answer these questions utilizes biochemistry and genetics; genetics to isolate mutants that have particular defects in development and biochemistry to determine the molecular basis of the defects. We study swarming in Myxococcus xanthus that builds fruiting bodies.
• 
  Kamaya, Aya 
  Academic Appointments Assistant Professor - Med Center Line,  Radiology - Diagnostic Radiology
  Member,  Stanford Cancer Institute
  Member,  Bio-X
  
  Clinical Focus

  • Oncologic Imaging
  • Hepatobiliary and pancreatic imaging
  • Urogenital imaging
  Research Interest

  Photoacoustic imaging of cancer Perfusion CT imaging of abdominal tumors
• 
  Kanevsky, Max 
  Academic Appointments Assistant Professor - Med Center Line,  Anesthesia
  Member,  Bio-X
  
  Clinical Focus

  • Anesthesia
  • Cardiovascular Anesthesia
  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Katila, Riitta 
  Academic Appointments Member,  Bio-X
  
• 
  Katzenstein, David 
  Academic Appointments Professor (Research),  Medicine - Infectious Diseases
  Member,  Bio-X
  
  Clinical Focus

  • Infectious Disease
  • Infectious Diseases
  Research Interest

  Treatment and evaluation of HIV infectionin the United States and Europe through the AIDS Clinical Trials Group (ACTG). International HIV pathogenesis work includes studies in Zimbabwe, South Africa, and India where we are particularly interested in the pandemic of subtype C HIV-1, TB and other co-infections. The lab currently is focused on drug resistance, envelope tropism and the pathogenesis of HIV.
• 
  Kay, Mark 
  Academic Appointments Professor,  Pediatrics - Human Gene Therapy
  Member,  Stanford Cancer Institute
  Member,  Bio-X
  Member,  Child Health Research Institute
  Professor,  Genetics
  
  Research Interest

  Mark A. Kay, M.D., Ph.D. Director of the Program in Human Gene Therapy and Professor in the Departments of Pediatrics and Genetics. Respected worldwide for his work in gene therapy for hemophilia, Dr. Kay and his laboratory focus on establishing the scientific principles and developing the technologies needed for achieving persistent and therapeutic levels of gene expression in vivo. The major disease models are hemophilia, hepatitis C, and hepatitis B viral infections.
• 
  Kenny, Thomas 
  Academic Appointments Member,  Bio-X
  
• 
  Kesler, Shelli 
  Academic Appointments Assistant Professor (Research),  Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research
  Member,  Bio-X
  Member,  Stanford Cancer Institute
  
  Clinical Focus

  • Psychology
  • Psychiatry
  Research Interest

  Assessment and treatment of cognitive deficits related to medical problems, particularly cancer. Multi-level research involving neuropsychology, neuroimaging and genetics. Measurement and enhancement of neuroplasticity mechanisms through targeted interventions.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Khatib, Oussama 
  Academic Appointments Member,  Bio-X
  
• 
  Khavari, Paul 
  Academic Appointments Professor,  Dermatology
  Member,  Stanford Cancer Institute
  Member,  Bio-X
  Member,  Child Health Research Institute
  
  Clinical Focus

  • Cancer  >  Cutaneous (Dermatologic) Oncology
  • Dermatology
  • General Dermatology
  Research Interest

  We work in epithelial tissue as a model system to study stem cell biology, cancer and new molecular therapeutics. Epithelia cover external and internal body surfaces and undergo constant self-renewal while responding to diverse environmental stimuli. Epithelial homeostasis precisely balances stem cell-sustained proliferation and differentiation-associated cell death, a balance which is lost in many human diseases, including cancer, 90% of which arise in epithelial tissues.
• 
  Khosla, Chaitan 
  Academic Appointments Professor,  Chemical Engineering - Chemical Engineering Operations
  Professor,  Natural Sciences Cluster - Chemistry
  Member,  Bio-X
  Professor (By courtesy),  Biochemistry
  
  Research Interest

  Research interests in this laboratory lie at the interface of chemistry and medicine. For the past several years, we have investigated the catalytic mechanisms of modular megasynthases such as polyketide synthases, with the concomitant goal of harnessing their programmable chemistry for preparing new antibiotics. Recent accomplishments include methods for heterologous production of polyketides; genetically reprogrammed biosynthesis of anthraquinones and polypropionates; and chemo-biosynthesi..
• 
  Kim, Seung 
  Academic Appointments Professor,  Developmental Biology
  Member,  Stanford Cancer Institute
  Member,  Bio-X
  Member,  Child Health Research Institute
  Professor (By courtesy),  Medicine - Oncology
  
  Research Interest

  We study the genetics of pancreatic islet cell differentiation using molecular, embryologic and genetic methods in several model systems, including mice, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. Our knowledge of genetic and cellular pathways governing islet formation has allowed us to use stem cell lines to produce islet replacements in vitro.
• 
  Kingsley, David 
  Academic Appointments Professor,  Developmental Biology
  Member,  Bio-X
  
  Research Interest

  My laboratory uses mice, stickleback fish, and humans to study the molecular basis of vertebrate evolution. Using genetics and genomics, we have tracked down key genes and mutations that control skeletal development, limb patterning, brain size evolution, skin color, salt handling, and susceptibility to arthritis and skin cancer. Many of these genetic mechanisms are used repeatedly, providing new insights into the molecular basis of evolution in many different species, including ourselves.
• 
  Knox, Susan 
  Academic Appointments Associate Professor,  Radiation Oncology - Radiation Therapy
  Member,  Stanford Cancer Institute
  Member,  Bio-X
  
  Clinical Focus

  • Cancer  >  Cutaneous (Dermatologic) Oncology
  • Cancer  >  Lymphoma
  • Cancer  >  Radiation Oncology
  Research Interest

  Our interests include 1) study of the effect of radiation on regulatory cell subpopulations and co-stimulatory molecules, 2) use of radiation as an immune modulator for optimization of transplant regimens, 3) the role of radiation in tumor vaccine strategies, 4) study of new radiosensitizers and radioprotectors, and 5) discovery of new targeted therapies for the treatment of solid tumors.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Knudsen, Eric 
  Academic Appointments Professor,  Neurobiology
  Member,  Bio-X
  
  Research Interest

  Cellular mechanisms of spatial attention and learning, studied in the central nervous system in birds, using behavioral, systems, cellular and molecular techniques.
• 
  Knutson, Brian 
  Academic Appointments Member,  Bio-X
  
• 
  Kobilka, Brian 
  Academic Appointments Professor,  Molecular & Cellular Physiology
  Member,  Bio-X
  Professor (By courtesy),  Chemical and Systems Biology
  
  Research Interest

  Structure, function and physiology of adrenergic receptors.
• 
  Kohler, Jennifer J
  Academic Appointments Member,  Bio-X
  
  Research Interest

  Glycosylation in the secretory pathway.
• 
  Koller, Daphne 
  Academic Appointments Member,  Bio-X
  
• 
  Kool, Eric 
  Academic Appointments Member,  Bio-X
  
• 
  Koong, Albert 
  Academic Appointments Associate Professor,  Radiation Oncology - Radiation Therapy
  Member,  Bio-X
  Member,  Stanford Cancer Institute
  
  Clinical Focus

  • Cancer  >  GI Oncology
  • Cancer  >  Radiation Oncology
  • Pancreatic Cancer
  Research Interest

  The focus of my laboratory is to understand the role of hypoxia and the tumor microenvironment on malignant progression. My clinical area of interest is in the application of chemoradiotherapy and stereotactic body radiotherapy (SBRT) for GI malignancies.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Kopito, Ron 
  Academic Appointments Professor,  Biology (School of Humanities and Sciences)
  Member,  Bio-X
  
  Research Interest

  Our research is concerned with elucidating the basic cellular molecular mechanisms that underly the recognition and destruction of misfolded or mis-assembled proteins in eukaryotic cells. We study dominatly inherited human neurodegenerative disorders like Alzheimer's, Huntington's or Parkinson's diseases that are caused by the failure of this system to effectively recognize and destroy such proteins.
• 
  Kornberg, Roger 
  Academic Appointments Professor,  Structural Biology
  Member,  Bio-X
  
  Research Interest

  We study the regulation of transcription, the first step in gene expression. The main lines of our work are 1) reconstitution of the process with more than 50 pure proteins and mechanistic analysis, 2) structure determination of the 50 protein complex at atomic resolution, and 3) studies of chromatin remodelling, required for transcription of the DNA template in living cells
• 
  Koseff, Jeffrey 
  Academic Appointments Member,  Bio-X
  
  Clinical Focus

  • General Surgery
• 
  Kraemer, Fredric 
  Academic Appointments Professor,  Medicine - Endocrinology, Gerontology, & Metabolism
  Member,  Bio-X
  
  Clinical Focus

  • Endocrinology / Diabetes
  • Lipid Metabolism Disorders
  • Endocrinology and Metabolism
  Research Interest

  Our research interests are in the general area of cellular lipid and lipoprotein metabolism. The work is aimed primarily at understanding the mechanisms regulating cholesterol and triglyceride accumulation in cells. We utilize a variety of techniques from cell biology, biochemistry, and molecular biology.
• 
  Krams, Sheri 
  Academic Appointments Associate Professor (Research),  Surgery - Multi-Organ Transplantation
  Member,  Child Health Research Institute
  Member,  Bio-X
  
  Research Interest

  Our recent studies have focused on three specific areas: 1) NK cell interactions with dendritic cells and tumors, 2) MicroRNAs as master regulators in transplantation and viral infections and 3) Mechanisms of tolerance induction.
• 
  Krasnow, Mark 
  Academic Appointments Professor,  Biochemistry
  Member,  Stanford Cancer Institute
  Member,  Bio-X
  
  Research Interest

  - Lung development and stem cells - Neural control of breathing - Lung diseases including lung cancer - New genetic model organisms for medicine
• 
  Krensky, Alan 
  Academic Appointments Emeritus Faculty, Acad Council,  Pediatrics
  Member,  Stanford Cancer Institute
  Member,  Bio-X
  
  Research Interest

  Mechanisms and therapies for infection, cancer, autoimmunity and transplantation.
• 
  Krummel, Thomas 
  Academic Appointments Professor,  Surgery - Pediatric Surgery
  Member,  Bio-X
  Professor (By courtesy),  Cardiothoracic Surgery - Adult Cardiac Surgery
  Professor (By courtesy),  Bioengineering
  
  Clinical Focus

  • Pediatric Surgery
  • Surgery, Pediatric
  Research Interest

  Surgical Innovation, Simulation and Virtual Reality in Surgical Education, Fetal Healing-Cellular and Biochemical Mechanisms

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Kuo, William 
  Academic Appointments Associate Professor - Med Center Line,  Radiology - Diagnostic Radiology
  Member,  Bio-X
  
  Clinical Focus

  • Vascular & Interventional Radiology
  • Complex IVC Filter Retrieval
  • Acute PE
  Research Interest

  1) LASER-ASSISTED AND COMPLEX IVC FILTER RETRIEVAL 2) CATHETER-DIRECTED THERAPY FOR ACUTE PULMONARY EMBOLISM 3) INTERNATIONAL PE REGISTRY 4) IVC FILTER REGISTRY 5) ENDOVASCULAR TREATMENT OF CAVAL AND DEEP VENOUS THROMBOSIS

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Kuo, Calvin Jay
  Academic Appointments Professor,  Medicine - Hematology
  Member,  Stanford Cancer Institute
  Member,  Child Health Research Institute
  Member,  Bio-X
  Professor (By courtesy),  Chemical and Systems Biology
  
  Clinical Focus

  • Cancer  >  Hematology
  • Medical Oncology
  Research Interest

  We explore angiogenesis, cancer genomics, intestinal stem cells, and hepatic glucose metabolism. Angiogenesis projects include endothelial miRNA and GPCR ko mice, blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy. Intestinal stem cell projects use primary intestinal culture and mouse genetics to study injury-inducible vs homeostatic stem cells. We use primary organoid cultures of diverse tissues for oncogene functional screening and therapeutics discovery.