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Academic Appointments Associate Professor, Neurobiology
Member, Bio-X
Research InterestWe study how the neural circuitry of the vertebrate retina encodes visual information and performs computations. To control and measure the retinal circuit, we present visual images while performing simultaneous two-photon imaging and multielectrode recording. We perturb the circuit as it operates using simultaneous intracellular current injection and multielectrode recording, and use the resulting large data sets to construct models of retinal computation.
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Research Interest
Our laboratory is focused on identifying proteins based upon their ability to alter a variety of cell fate decisions - including mesodermal, endodermal, neural, endothelial, and somitic - within the vertebrate embryo.
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Academic Appointments Professor Emeritus, Biology (School of Humanities and Sciences)
Member, Bio-X
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Academic Appointments Member, Bio-X
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Academic Appointments Professor, Neurobiology
Member, Bio-X
Professor, Developmental Biology
Professor, Neurology & Neurological Sciences
Research InterestOur lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system.
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Academic Appointments Associate Professor, Bioengineering
Member, Stanford Cancer Institute
Member, Bio-X
Research InterestBiophysical mechanisms of host defense peptides and their mimics
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Academic Appointments Professor Emeritus, Genetics
Emeritus Faculty, Acad Council, Genetics
Member, Bio-X
Clinical Focus- Cancer Genetics
- Clinical Genetics
Research InterestGenetics of color variation
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Academic Appointments Assistant Professor, Medicine - Stanford Prevention Research Center
Member, Bio-X
Clinical Focus- General Internal Medicine
Research Interestmathematical models econometrics global health social determinants of health health policy
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Academic Appointments Member, Bio-X
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Academic Appointments Professor, Biochemistry
Member, Bio-X
Professor, Developmental Biology
Research InterestFunction of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation), in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells.
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Academic Appointments Professor - Med Center Line, Radiology - Diagnostic Radiology
Member, Bio-X
Member, Stanford Cancer Institute
Professor - Med Center Line (By courtesy), Orthopaedic Surgery
Clinical Focus- Diagnostic Radiology
- Radiology
Research InterestApplications of computer graphics to medical imaging, with emphasis on diagnosis of bowel pathology using virtual colonoscopy. Dynamic joint imaging with open Magnetic Resonance Imaging system.
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Professor - Med Center Line, Obstetrics & Gynecology - Reproductive Endocrinology & Infertility
Member, Bio-X
Clinical Focus- Fertility (Reproductive Medicine)
- Obstetrics & Gynecology
Research InterestDevelopment of improved embryo culture conditions in vitro. Blastocyst cultures. Embryo metabolism in vitro. Embryo maternal dialogue. Clinical application and integration of extended embryo culture systems. Monozygotic twinning. Prevention of multiple pregnancy. Sperm motility enhancers. Fluorescent and non-fluorescent markers of sperm morphology and viablility. Oocyte cryopreservation. Fertility preservation. Improving IVF outcome.
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Academic Appointments Assistant Professor, Developmental Biology
Assistant Professor, Computer Science
Member, Bio-X
Member, Stanford Cancer Institute
Research InterestDr. Bejerano, co-discoverer of ultraconserved elements, studies the Human Genome. Through computation and experimentation we investigate the Systems Biology parts-list of many thousands genomic regions involved in gene transcription regulation during embryonic development. Major interests include (1) the origins and evolution of these regions, (2) how they encode their individual as well as combined roles, (3) their contribute to human disease, and (4) their contribute to species adaptation.
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Academic Appointments Assistant Professor - Med Center Line, Medicine - Blood & Marrow Transplantation
Member, Bio-X
Clinical Focus- Cancer > Blood and Marrow Transplant
- Blood and Marrow Transplantation
- Internal Medicine
Research InterestMy research interests adoptive transfer of defined subsets of lymphocytes for the treatment of hematologic malignancies. I have a specific interest in the treatment of Myelodysplastic Syndromes with non-myeloablative and reduced intensity transplant conditioning regimens.
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Academic Appointments Member, Bio-X
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Academic Appointments Member, Bio-X
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Academic Appointments Associate Professor, Biology (School of Humanities and Sciences)
Member, Bio-X
Research InterestWe use genetic, genomic and cell biological approaches to study cell fate acquisition, focusing on cases where cell fate is correlated with asymmetric cell division.
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Academic Appointments Professor, Pediatrics - Cardiology
Member, Child Health Research Institute
Member, Stanford Cancer Institute
Member, Bio-X
Clinical Focus- Pediatric Cardiology
- Pediatric Heart Transplantation
- Pediatric Heart Failure
Research Interest1. Role of the G protein coupled receptors in regulating mitochondrial structure and function. 2. Differences between R and L ventricular responses to stress, including gene expression and miR regulation. 3. Using iPSC-derived myocytes to understand heart failure and congenital heart disease. 4. Tools for evaluation of cardiac physiology in transgenic mice and isolated cardiomyocytes. 5. Anti-body mediated rejection. 6. Biomarkers for post-transplant lymphoproliferative disorder.
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Professor - Med Center Line, Pediatrics - Gastroenterology
Member, Bio-X
Clinical Focus- Pediatric Gastroenterology
- Ped Gastroenterology
Research InterestGastroenterology, gastointestinal motility, clinical management of pediatric liver transplant recipients.
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Associate Professor - Med Center Line, Anesthesia
Professor - Med Center Line, Anesthesia
Member, Bio-X
Academic Appointments Associate Professor at PAVAHCS, Anesthesia
Clinical Focus- Anesthesia
Research Interestmolecular modeling of anesthetic-protein interactions, molecular modeling of the ligand-gated ion channels
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Academic Appointments Associate Professor - Med Center Line, Cardiothoracic Surgery - Adult Cardiac Surgery
Associate Professor - Med Center Line, Surgery
Member, Bio-X
Clinical Focus- Heart and Lung Transplantation
- Valvular Heart Diseases
- Adult Cardiac Surgery
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Assistant Professor - Med Center Line, Orthopaedic Surgery
Member, Bio-X
Clinical Focus- Orthopaedic Surgery
- Orthopaedic Trauma Surgery
- Fracture Fixation
Research InterestDr. Bishop specializes in treating fractures of the upper extremity, lower extremity, pelvis and acetabulum as well as the management of post-traumatic problems including malunion, nonunion and infection. He received his undergraduate and medical school degrees from Harvard University and went on to complete the Harvard Combined Orthopaedic Surgery Residency Program. He pursued his subspecialty training in Orthopaedic Traumatology at the world-renowned Harborview Medical Center in Seattle,..
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Associate Professor - Med Center Line, Radiology - Diagnostic Radiology
Member, Bio-X
Clinical Focus- Diagnostic Radiology
- Radiology
Research InterestChronic pain sufferers are unfortunately limited by poor diagnostic tests and therapies. Our lab is interested in 'imaging pain' by using multimodality molecular imaging techniques to study nociception and neuronal inflammation as a means of improving objective, image-guided diagnosis and treatment of chronic pain disorders. We develop new molecular contrast agents for use in positron emission tomography (PET) and magnetic resonance imaging (MRI), working towards eventual clincal translation.
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Professor, Microbiology & Immunology - Baxter Laboratory
Member, Stanford Cancer Institute
Member, Bio-X
Research InterestProf. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.
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Academic Appointments Member, Bio-X
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Academic Appointments Assistant Professor, Medicine - Infectious Diseases
Member, Child Health Research Institute
Member, Bio-X
Clinical Focus- Infectious Disease
Research InterestThe major goal of our research is to gain insight into the prevention and control of HIV and other viral pathogens by studying the interplay between the virus and the host immune response. We investigate the role of various arms of the immune response, but with a particular focus on NK cells. We hope to gain additional insights into control of infectious diseases by studying how pregnancy modulates immune responses.
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Academic Appointments Professor, Natural Sciences Cluster - Applied Physics
Professor, Biology (School of Humanities and Sciences)
Member, Bio-X
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Academic Appointments Professor - Med Center Line, Ophthalmology
Member, Bio-X
Clinical Focus- Ophthalmology
- Macular and Vitreoretinal Diseases
Research InterestClinical Interest and Research My primary areas of interest are in the diagnosis, medical and surgical treatment of vitreal retinal diseases. These principally include age-related macular degeneration and other diseases of the macula, and tractional syndromes, diabetic retinopathy, and complex forms of retinal detachment. I have been interested in the development of novel technology to diagnose and treat these diseases, including new forms of imaging, laser delivery systems, other microsurgi..
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Associate Professor, Bioengineering
Member, Bio-X
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Academic Appointments Member, Bio-X
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Academic Appointments Professor (Teaching), Biology (School of Humanities and Sciences)
Member, Bio-X
Research InterestI am interested in how environmental variation affects life history traits, population structure and dynamics, and species interactions in ecological and evolutionary time, using Lepidoptera.
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Academic Appointments Professor, Pathology
Member, Stanford Cancer Institute
Member, Bio-X
Professor, Microbiology & Immunology
Professor (By courtesy), Chemical and Systems Biology
Research InterestOur lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include: 1) Design and synthesis of novel chemical probes for each of the primary protease families. 2) Understanding the role of proteolysis in the life cycle of the human parasites, Plasmodium falciparum and Toxoplasma gondii. 3) Defining the specific functional roles of proteases during the process of tumorogenesis. 4) In vivo imaging of protease activity
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Academic Appointments Associate Professor - Med Center Line, Surgery - Multi-Organ Transplantation
Member, Bio-X
Member, Child Health Research Institute
Clinical Focus- General Surgery
- Liver Transplantation
- Live-donor Liver Transplantation
Research InterestTolerance induction in liver transplantation. Hepatocyte transplantation.
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Professor, Microbiology & Immunology
Member, Stanford Cancer Institute
Member, Child Health Research Institute
Member, Bio-X
Research InterestWe are intereseted in the interaction between the protozoan parasite Toxoplasma gondii and its mammalian host. We use a combination of molecular and genetic tools to understand how this obligate intracellular parasite can invade almost any cell it encounters, how it co-opts a host cell once inside and how it evades the immune response to produce a life-long, persistent infection.
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Academic Appointments Professor, Medicine - Hematology
Member, Stanford Cancer Institute
Member, Bio-X
Clinical Focus- Cancer > Hematology
- Hematology
- Multiple Myeloma
Research InterestRegulation of expression of oncogenes in normal and malignant hematologic cells.
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Academic Appointments Member, Bio-X
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Academic Appointments Assistant Professor - Med Center Line, Pathology
Member, Bio-X
Member, Child Health Research Institute
Clinical Focus- Hematopathology
Research InterestThe lymphocytes of the human immune system share some biological properties with human cancers: in each case, there are subpopulations of cells whose genomes are rearranged and mutated compared to other cells in the body. Our goal is to understand the genotype-phenotype relationships in lymphoid cells that determine the behavior of human diseases. We apply new analytical methods, particularly high-throughput DNA sequencing, in parallel with functional assays, to tackle this challenge.
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Member, Bio-X
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Academic Appointments Professor - Med Center Line, Neurology & Neurological Sciences
Member, Bio-X
Professor - Med Center Line (By courtesy), Neurosurgery
Clinical Focus- Neurology
- movement disorders
Research InterestMy research focus is human motor control and brain pathophysiology in movement disorders. Our overall goal is to understand the role of the basal ganglia electrical activity in the pathogenesis of movement disorders. We have developed novel computerized technology to measure fine, limb and postural movement. With these we are measuring local field potentials in basal ganglia nuclei in patients with Parkinson's disease and dystonian and correlating brain signalling with motor behavior.
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Academic Appointments Professor, Urology
Member, Stanford Cancer Institute
Member, Bio-X
Clinical Focus- Cancer > Urologic Oncology
- Male Cancers - Prostate
- Prostate Cancer
Research InterestWe use genomic approaches to identify disease biomarkers. We are most interested in translating biomarkers into clinical practice in urological diseases with a particular focus in cancer.
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Academic Appointments Member, Bio-X
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Academic Appointments Associate Professor, Genetics
Member, Stanford Cancer Institute
Member, Bio-X
Research InterestOur lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.
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Academic Appointments Professor, Molecular & Cellular Physiology
Professor, Stanford Synchrotron Radiation Lightsource - SSRL
Member, Bio-X
Professor, Neurology & Neurological Sciences
Professor (By courtesy), Structural Biology
Research InterestAxel Brunger's goal is to understand the molecular mechanism of synaptic neurotransmission. He is particularly interested in the structure, function, and dynamics of key players in the synaptic vesicle fusion machinery. His lab is also working on the mechanism of action of clostridial neurotoxins that target this machinery. A molecular understanding of these complex protein machineries may ultimately lead to new therapeutics to treat human diseases.
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Academic Appointments Professor Emeritus, Biochemistry
Member, Bio-X
Research InterestMy primary interest is to understand the flow of information from the genome to the phenotype of an organism. This interest includes predicting the structure and function of genes and proteins from their primary sequence, predicting function from structure and finally simulating protein folding and ligand docking. These goals are the same as the goals of molecular biology, however, we use primarily computational approaches.
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Academic Appointments Assistant Professor, Bioengineering
Member, Bio-X
Assistant Professor (By courtesy), Structural Biology
Research InterestMolecular motors lie at the heart of biological processes from DNA replication to vesicle transport. My laboratory seeks to understand the physical mechanisms by which these nanoscale machines convert chemical energy into mechanical work.
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Academic Appointments Professor, Comparative Medicine
Member, Bio-X
Professor, Neurology & Neurological Sciences
Research InterestMechanisms of epilepsy, especially temporal lobe epilepsy.
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Academic Appointments Professor, Genetics
Member, Bio-X
Professor (By courtesy), Biology (School of Humanities and Sciences)
Research InterestMy research focuses on analyzing genome wide patterns of variation within and between species to address fundamental questions in biology, anthropology, and medicine. My group works on a variety of organisms and model systems ranging from humans and other primates to domesticated plant and animals. Much of our research is at the interface of computational biology, mathematical genetics, and evolutionary genomics.
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Academic Appointments Professor, Pathology
Member, Stanford Cancer Institute
Member, Bio-X
Clinical Focus- Pathology Anatomic
- Pathology and Laboratory Medicine
Research InterestOur interests include: 1) The physiology and significance of lymphocyte homing in local and systemic immunity; 2) biochemical and genetic studies of molecules that direct leukocyte recruitment; 3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines; 4) vascular differentiation in normal and pathologic inflammatory states; 5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs.
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Academic Appointments Associate Professor, Pediatrics - Systems Medicine
Member, Stanford Cancer Institute
Member, Child Health Research Institute
Member, Bio-X
Associate Professor, Genetics
Associate Professor (By courtesy), Computer Science
Associate Professor (By courtesy), Medicine - Immunology & Rheumatology
Research InterestThe Butte Lab at Stanford builds and applies tools that convert more than 300 billion points of molecular, clinical, and epidemiological data -- measured by researchers and clinicians over the past decade -- into diagnostics, therapeutics, and new insights into disease.
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Academic Appointments Assistant Professor, Pediatrics - Immunology and Allergy
Member, Child Health Research Institute
Member, Bio-X
Member, Stanford Cancer Institute
Clinical Focus- Allergy and Immunology
- Pediatric Allergy/Immun
Research InterestOur laboratory's goal is to address fundamental and therapeutic questions in immunology using innovative nanotechnological and biophysical approaches to visualize and manipulate cells. Our primary focus is on understanding the molecular controls that balance T cell activation versus tolerance. The ultimate aim of our work is to manipulate T cell signaling pathways to control immunologically-mediated diseases.
Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital -
Academic Appointments Member, Bio-X
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