Charles DeBattista
Ropinirole Controlled Release (CR) as an Adjunctive Agent in the Treatment of Major Depression
Contact Information
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Brief
This is an 8 week study for patients who are currently taking antidepressant medication but not fully responding. Ropinirole CR would be taken in conjunction with current antidepressant medication. Patients come into the clinic once a week when starting on the medication and then once every other week for the remainder of the 8 weeks.
Recruiting Status:
CompletedStanford Recruiting Status:
No longer recruitingCondition(s):
Intervention(s):
- Drug: Ropinirole CR
Phase:
N/AEligibility
Ages Eligible for Study:
18 years to 65 yearsGenders Eligible for Study:
Male and FemaleHealth of Volunteers:
People with the conditions listed in this trial can participate as controls.Key Inclusion Criteria:
1. Age 18 to 65 years old
2. Currently experiencing major depression
3. On at least an adequate dose of fluoxetine, paroxetine, sertraline, citalopram, escitalopram, venlafaxine, bupropion, mirtazapine or duloxetine for at least 6 weeks (monotherapy).
Key Exclusion Criteria:
1. Pregnant females or females of child bearing years not using adequate birth control in the opinion of the investigators
2. Known sensitivity to ropinirole
3. Significant medical conditions that would preclude safe participation in the study in the opinion of the investigators.
4. Significant abnormalities observed in screening laboratory evaluation
Additional Study Details
Official Title:
Ropinirole Controlled Release (CR) as an Adjunctive Agent in the Treatment of Major DepressionAnticipated start date:
1/1/2006Lead Sponsor:
Stanford UniversityCollaborator(s):
- Duke University
- GSK
Investigator(s):
Study Type:
InterventionalPurpose:
TreatmentAllocation:
Non-randomizedMasking:
OpenControl:
noneAssignment:
Single GroupEndpoints:
Safety/EfficacyPrimary Outcomes:
- HamD
Secondary Outcomes:
- MADRS
Total Number to be Enrolled:
60Total Number to be Enrolled at Stanford:
30More Information
Locations & Contacts
Stanford Locations & Contacts:
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Non-Stanford Locations:
This study is being conducted at multiple locations, including non-Stanford locations.
This listing was last updated:
5/14/2008PLEASE NOTE:
Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician. If you do not have a primary care physician please feel free to call the SHC Physician Referral Service at (800) 756-9000 or send an email.
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