Stanley Schrier
Red Cell Mass and Plasma Volume Measurements in Elderly Men and Women with Unexplained Anemia
Contact Information
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Brief
Approximately one third of elderly patients with anemia have anemia without discernable etiology, that is, ?unexplained anemia?, typically defined by the hemoglobin concentration via a blood sample. However, the question of whether the hemoglobin concentration itself accurately represents the underlying red cell mass in elderly patients with unexplained anemia has not previously been addressed. This question has arisen because the clinical consequences of seemingly trivial levels of anemia are surprisingly severe. We wish to test this hypothesis by measuring the true red cell mass and plasma volume in elderly with unexplained anemia and compare this value with the routine clinical measurement of hemoglobin.
Recruiting Status:
RecruitingStanford Recruiting Status:
RecruitingCondition(s):
Intervention(s):
Phase:
N/AEligibility
Ages Eligible for Study:
65 years to Any AgeGenders Eligible for Study:
Male and FemaleHealth of Volunteers:
People with the conditions listed in this trial can participate as controls.Key Inclusion Criteria:
Age 65 and older
Unexplained anemia (Hb < 12 g/dL in women, < 13 g/dL in men, no etiology for anemia found, as
determined in the "Anemia in the Elderly" study, PI S. Schrier)
Outpatient at either the VAPAHCS or SHC
Key Exclusion Criteria:
BMI (kg/m2) < 18.5 and > 35
Palpable splenomegaly
Contraindication to RBC mass/plasma volume testing
On any experimental pharmacalogic agent in the prior 2 months
Additional Study Details
Official Title:
Red Cell Mass and Plasma Volume Measurements in Elderly Men and Women with Unexplained AnemiaAnticipated start date:
4/28/2009Lead Sponsor:
Stanford UniversityInvestigator(s):
Study Type:
ObservationalPurpose:
NOTNEEDEDDuration:
Cross-sectionalSelection:
Defined PopulationTiming:
ProspectiveTotal Number to be Enrolled:
12Total Number to be Enrolled at Stanford:
12More Information
Locations & Contacts
Stanford Locations & Contacts:
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Non-Stanford Locations:
The Stanford website does not have any locations outside of Stanford listed for this trial. You may want to check clinicaltrials.gov for posible additional locations.
This listing was last updated:
11/6/2009PLEASE NOTE:
Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician. If you do not have a primary care physician please feel free to call the SHC Physician Referral Service at (800) 756-9000 or send an email.
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