Jerome Yesavage
Alzheimer's Disease Neuroimaging Initiative (ADNI)
Contact Information
VA Palo Alto Health Care System 3801 Miranda Avenue Palo Alto, CA 94304Brief
The overall goals of the Alzheimer?s Disease Neuroimaging Initiative (ADNI) Clinical Protocol will be to recruit 800 subjects and carry out all clinical evaluations including: neuropsychological and clinical assessments, imaging studies and collection of biomarkers.
Recruiting Status:
No longer recruitingStanford Recruiting Status:
Condition(s):
Intervention(s):
- Procedure: results of MRI and PET scans
Phase:
N/AEligibility
Ages Eligible for Study:
55 years to 90 yearsGenders Eligible for Study:
Male and FemaleHealth of Volunteers:
People with the conditions listed in this trial can not participate as controls.Key Inclusion Criteria:
Enrolled subjects will be between 55-90 (inclusive) years of age,
have a study partner able to provide an independent evaluation of
functioning, and will speak either English or Spanish. All subjects
must be willing and able to undergo all test procedures including
neuroimaging and agree to longitudinal follow up. Between
twenty and fifty percent must be willing to undergo two lumbar
punctures. Specific psychoactive medications will be excluded.
General inclusion/exclusion criteria are as follows:
1. Normal subjects: MMSE scores between 24-30 (inclusive), a CDR of 0, non-depressed, non-MCI, and nondemented.
2. MCI subjects: MMSE scores between 24-30 (inclusive), a memory complaint, have objective memory loss measured by education adjusted scores on Wechsler Memory Scale Logical Memory levels of impairment essentially preserved absence of dementia.
3. Mild AD: MMSE of 0.5 or 1.0, probable AD.
Key Exclusion Criteria:
Exclusion criteria include recent alcohol abuse, major psychiatric disorders, and any condition contraindicating MRI, PET, or lumbar puncture.
Additional Study Details
Official Title:
Alzheimer's Disease Neuroimaging Initiative (ADNI)Anticipated start date:
5/1/2005Lead Sponsor:
UCSFCollaborator(s):
- UCSD; Alzheimer's Disease Cooperative Studies
Investigator(s):
Study Type:
ObservationalPurpose:
NOTNEEDEDDuration:
LongitudinalSelection:
Random SampleTiming:
ProspectiveTotal Number to be Enrolled:
800Total Number to be Enrolled at Stanford:
5More Information
Secondary ID(s):
- 1722
Locations & Contacts
Stanford Locations & Contacts:
VA Palo Alto Health Care System 3801 Miranda Avenue Palo Alto, CA 94304Non-Stanford Locations:
The Stanford website does not have any locations outside of Stanford listed for this trial. You may want to check clinicaltrials.gov for posible additional locations.
This listing was last updated:
7/1/2009PLEASE NOTE:
Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician. If you do not have a primary care physician please feel free to call the SHC Physician Referral Service at (800) 756-9000 or send an email.
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