Paul Keall, Ph.D.
Feasibility of Using Real-time Cine-MRI for Treating Moving & Deforming Tumors
Contact Information
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Brief
This study aims to investigate and optimize imaging sequences and parameters of rapid real-time MRI in order to obtain adequate guidance for accurately and precisely delivering radiation to moving abdominal and thoracic tumors.
Recruiting Status:
RecruitingStanford Recruiting Status:
RecruitingCondition(s):
Intervention(s):
- Procedure: MR Imaging
Phase:
N/AEligibility
Ages Eligible for Study:
18 years to Any AgeGenders Eligible for Study:
Male and FemaleHealth of Volunteers:
People with the conditions listed in this trial can participate as controls.Key Inclusion Criteria:
3.1.1. Eligible disease(s)/stage(s) AJCC Stage I, II, III or IV lung, liver or pancreatic cancer of any histology to be treated using radiotherapy will be eligible for this study.
3.1.2. Allowable type and amount of prior therapy  Any types and amounts of prior therapy will be allowed for this study.
3.1.3. Age restriction and/or gender/ethnic restrictions Patients must be greater than or equal to 18 years of age. There are no gender or ethnic restrictions.
3.1.4. Life expectancy restrictions  None.
3.1.5. ECOG or Karnofsky Performance Status  Karnofsky performance status of 50 or greater
3.1.6. Requirements for organ and marrow function  None.
3.1.7. Ability to understand and the willingness to sign a written informed consent document.
3.1.8. Pain-free in supine position
Key Exclusion Criteria:
3.2.1 Children (age <18)
3.2.2 Metallic implants, embedded metallic objects, implanted biomedical devices e.g., cardiac pacemakers
3.2.3 Women who are pregnant or trying to get pregnant
3.2.4 Pain in supine position
3.2.5 Karnofsky performance status < 50
Additional Study Details
Official Title:
Investigating the Feasibility of Using Real-time Cine-MRI for Treating Moving and Deforming TumorsAnticipated start date:
2/10/2009Lead Sponsor:
Stanford UniversityCollaborator(s):
- American Association of Physicists in Medicine
Investigator(s):
Study Type:
InterventionalPurpose:
OtherAllocation:
Non-randomizedMasking:
OpenControl:
noneAssignment:
Single GroupEndpoints:
SafetyPrimary Outcomes:
- To investigate and optimize imaging sequences and parameters of rapid real-time MRI in order to obtain adequate guidance for accurately and precisely delivering radiation to moving thoracic and abdominal tumors.
Secondary Outcomes:
- To investigate the amount of degradation in MRI image contrast and spatial resolution (corresponding to lower field strength and/or faster acquisition speed) that provides real-time tumor position within 2 mm of the corresponding undegraded image.
Total Number to be Enrolled:
15Total Number to be Enrolled at Stanford:
15More Information
Secondary ID(s):
- VAR0042
Locations & Contacts
Stanford Locations & Contacts:
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Non-Stanford Locations:
The Stanford website does not have any locations outside of Stanford listed for this trial. You may want to check clinicaltrials.gov for posible additional locations.
This listing was last updated:
6/19/2009PLEASE NOTE:
Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician. If you do not have a primary care physician please feel free to call the SHC Physician Referral Service at (800) 756-9000 or send an email.
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