Andrew Quon
Evaluating Sunitinib Therapy in Renal Cell Carcinoma Using F-18 FDG PET/CT and DCE MRI
Contact Information
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Brief
To learn whether FDG PET/CT and DCE MRI are better predictors of response to therapy than the current standard of care (CT or MRI).
Recruiting Status:
RecruitingStanford Recruiting Status:
RecruitingCondition(s):
Intervention(s):
- Drug: Sunitinib
- Procedure: FDG PET
- Procedure: PET/CT
Phase:
N/AEligibility
Ages Eligible for Study:
18 years to Any AgeGenders Eligible for Study:
Male and FemaleHealth of Volunteers:
People with the conditions listed in this trial can participate as controls.Key Inclusion Criteria:
- Measurable disease by RECIST criteria
- Pathologic diagnosis of renal cell cancer
- Advanced (stage IV) renal cell cancer
- Karnofsky performance status of (KPS>70)
- Consent to participate in the clinical trial
Key Exclusion Criteria:
- Patients who cannot complete a PET/CT scan.
- Pregnant women.
- Healthy volunteers.
- Patients participating in other research protocols will be excluded from this study.
- Metallic implants (prosthesis, ICD, pacemakers), since these are contraindications for MRI.
Additional Study Details
Official Title:
Evaluating Sunitinib Therapy in Renal Cell Carcinoma using F-18 FDG PET/CT and DCE MRIAnticipated start date:
10/27/2007Lead Sponsor:
Stanford UniversityCollaborator(s):
- NCCN - National Comprehensive Cancer Network
Investigator(s):
Study Type:
InterventionalPurpose:
DiagnosticAllocation:
Non-randomizedMasking:
OpenControl:
noneAssignment:
Single GroupEndpoints:
Safety/EfficacyPrimary Outcomes:
- histopathology
- tumor size
- degree of tumor necrosis
- PET/CT (tumor size ? FDG uptake)
- MRI (tumor size)
- DCE MRI (AUC - peak flow)
Secondary Outcomes:
- initial imaging tumor size
- initial metabolic panel measures
- adverse events
Total Number to be Enrolled:
20Total Number to be Enrolled at Stanford:
20More Information
Secondary ID(s):
- 97807
- NCT00537056
- RENAL0013
Locations & Contacts
Stanford Locations & Contacts:
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Non-Stanford Locations:
The Stanford website does not have any locations outside of Stanford listed for this trial. You may want to check clinicaltrials.gov for posible additional locations.
This listing was last updated:
9/2/2009PLEASE NOTE:
Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician. If you do not have a primary care physician please feel free to call the SHC Physician Referral Service at (800) 756-9000 or send an email.
Help