Key Documents
Stephan Gehrke
Professional Education
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Doctor of Philosophy, Philipps-Universitat Marburg/Lahn
(2003)
Publications
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Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease.
Venderova K,
Kabbach G, Abdel-Messih E, Zhang Y, Parks RJ, Imai Y, Gehrke S, Ngsee J, Lavoie MJ, Slack RS, Rao Y, Zhang Z, Lu B, Haque ME, Park DS.
Hum Mol Genet.
2009;
18
(22):
4390-404
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Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila.
Imai Y,
Gehrke S, Wang HQ, Takahashi R, Hasegawa K, Oota E, Lu B.
EMBO J.
2008;
27
(18):
2432-43
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Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin.
Yang Y,
Gehrke S, Imai Y, Huang Z, Ouyang Y, Wang JW, Yang L, Beal MF, Vogel H, Lu B.
Proc Natl Acad Sci U S A.
2006;
103
(28):
10793-8
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Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling.
Yang Y,
Gehrke S, Haque ME, Imai Y, Kosek J, Yang L, Beal MF, Nishimura I, Wakamatsu K, Ito S, Takahashi R, Lu B.
Proc Natl Acad Sci U S A.
2005;
102
(38):
13670-5